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Q8PT98

- TRPF1_METMA

UniProt

Q8PT98 - TRPF1_METMA

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase 1

Gene

trpF1

Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciMMAZ192952:GCK2-2880-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase 1 (EC:5.3.1.24)
Short name:
PRAI 1
Gene namesi
Name:trpF1
Ordered Locus Names:MM_2819
OrganismiMethanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Taxonomic identifieri192952 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
ProteomesiUP000000595: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 234234N-(5'-phosphoribosyl)anthranilate isomerase 1PRO_0000154405Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi192952.MM_2819.

Structurei

3D structure databases

ProteinModelPortaliQ8PT98.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.Curated

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiHDHRISQ.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8PT98-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRKRLKTRIK ICGMCSPEDM EMAALYGADA VGFITEVPIE SPRKLDSDTA
60 70 80 90 100
ASLISKLPEC LDSVMVIMPE NSSRALELIE KVRPDIVQIH SNLPSVELEV
110 120 130 140 150
IREKTDIPII KTLSVPAGMG ASRVQSPVKR LLDEVRRLEE SGVVDSILLD
160 170 180 190 200
SGIAGKTGGT GYVHDWDLSR RIADETELPL ILAGGLKPEN VQEAIRIVSP
210 220 230
YAVDAASGVE ILGKKDAVKI RSFIEEVRCA NAFL
Length:234
Mass (Da):25,506
Last modified:October 1, 2002 - v1
Checksum:i89D47E76FBC3402D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008384 Genomic DNA. Translation: AAM32515.1.
RefSeqiNP_634843.1. NC_003901.1.
WP_011034727.1. NC_003901.1.

Genome annotation databases

EnsemblBacteriaiAAM32515; AAM32515; MM_2819.
GeneIDi1481161.
KEGGimma:MM_2819.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008384 Genomic DNA. Translation: AAM32515.1 .
RefSeqi NP_634843.1. NC_003901.1.
WP_011034727.1. NC_003901.1.

3D structure databases

ProteinModelPortali Q8PT98.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 192952.MM_2819.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM32515 ; AAM32515 ; MM_2819 .
GeneIDi 1481161.
KEGGi mma:MM_2819.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi HDHRISQ.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci MMAZ192952:GCK2-2880-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea."
    Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A., Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C., Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S., Bhattacharyya A., Lykidis A., Overbeek R.
    , Klenk H.-P., Gunsalus R.P., Fritz H.-J., Gottschalk G.
    J. Mol. Microbiol. Biotechnol. 4:453-461(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88.

Entry informationi

Entry nameiTRPF1_METMA
AccessioniPrimary (citable) accession number: Q8PT98
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: October 1, 2002
Last modified: October 29, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3