Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8PRX4

- TRPF2_METMA

UniProt

Q8PRX4 - TRPF2_METMA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

N-(5'-phosphoribosyl)anthranilate isomerase 2

Gene

trpF2

Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciMMAZ192952:GCK2-3379-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase 2 (EC:5.3.1.24)
Short name:
PRAI 2
Gene namesi
Name:trpF2
Ordered Locus Names:MM_3314
OrganismiMethanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Taxonomic identifieri192952 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
ProteomesiUP000000595: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 226226N-(5'-phosphoribosyl)anthranilate isomerase 2PRO_0000154406Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi192952.MM_3314.

Structurei

3D structure databases

ProteinModelPortaliQ8PRX4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.Curated

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiKICCISS.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8PRX4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRIKVCGIKR VEDAVMAAYC GADAIGLVVG RKHNSDDFID KHLAQKIVRE
60 70 80 90 100
CPPYISPVLV TELDDAEEIS GLVHETGVTS VQLHSDCTVD SIISLRKTFP
110 120 130 140 150
NIKIIKNFHV IGPGVIHAMK PFESVVDAFI LDTLDLANDK VGSTGLVHDW
160 170 180 190 200
SISRKIVKEV SRPVILAGGL TPENVGEAIR VVNPYGVDAS SGLKDSNGFK
210 220
DEMKVINFVH RAKNDFFKVR NLSLEN
Length:226
Mass (Da):24,760
Last modified:March 25, 2003 - v2
Checksum:i1EE6D057BEA7536E
GO

Sequence cautioni

The sequence AAM33010.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008384 Genomic DNA. Translation: AAM33010.1. Different initiation.
RefSeqiNP_635338.1. NC_003901.1.

Genome annotation databases

EnsemblBacteriaiAAM33010; AAM33010; MM_3314.
GeneIDi1481656.
KEGGimma:MM_3314.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008384 Genomic DNA. Translation: AAM33010.1 . Different initiation.
RefSeqi NP_635338.1. NC_003901.1.

3D structure databases

ProteinModelPortali Q8PRX4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 192952.MM_3314.

Protocols and materials databases

DNASUi 1481656.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM33010 ; AAM33010 ; MM_3314 .
GeneIDi 1481656.
KEGGi mma:MM_3314.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi KICCISS.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci MMAZ192952:GCK2-3379-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea."
    Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A., Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C., Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S., Bhattacharyya A., Lykidis A., Overbeek R.
    , Klenk H.-P., Gunsalus R.P., Fritz H.-J., Gottschalk G.
    J. Mol. Microbiol. Biotechnol. 4:453-461(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88.

Entry informationi

Entry nameiTRPF2_METMA
AccessioniPrimary (citable) accession number: Q8PRX4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: March 25, 2003
Last modified: October 1, 2014
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3