Reviewed, UniProtKB/Swiss-Prot Q8PPY3 (GLNE_XANAC)

Names and origin

Protein names

Recommended name:
    Glutamate-ammonia-ligase adenylyltransferase
    EC=2.7.7.42
Alternative name(s):
    [Glutamate--ammonia-ligase] adenylyltransferase
    Glutamine-synthetase adenylyltransferase
      Short name=ATase

Gene names

Name:	glnE
Ordered Locus Names:	XAC0550

Organism

Xanthomonas axonopodis pv. citri (Citrus canker) [Complete proteome] [HAMAP]

Taxonomic identifier

92829 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas

Protein attributes

Sequence length	941 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Adenylation and deadenylation of glutamine synthetase By similarity.
Catalytic activity	ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]. HAMAP MF_00802
Sequence similarities	Belongs to the glnE family.

Ontologies

Keywords
Domain	Repeat
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW [glutamate-ammonia-ligase] adenylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 941	941	Glutamate-ammonia-ligase adenylyltransferase HAMAP MF_00802		PRO_0000209285
Regions
	Region	92 – 301	210	GlnE 1 HAMAP MF_00802
	Region	599 – 815	217	GlnE 2 HAMAP MF_00802

Sequences

	Sequence		Length	Mass (Da)
	Q8PPY3-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 9249F9740229C2F8	FASTA	941	102,806
	10 20 30 40 50 60 MPMPTVSMSP ALTALIERAV ARVRQSLPVE QAWPGGEFDR QLAQVALASE FALDTLARQP 70 80 90 100 110 120 ALLQHLAQPD PPPLPLPQFD PAQPQLWPAQ LRRYRSAEST RLVWRDVLGL DSVEATLAGA 130 140 150 160 170 180 TQLAEHCLQC GLQALEQQFH TRHGKVVAAD GSVQRLVVFG LGKLGGGELN FSSDVDLVYA 190 200 210 220 230 240 YPQGGQSDGA RPLAAEEYFA RLGQQLARLL DETTADGFSH RVDLRLRPFG TAGRVALSFA 250 260 270 280 290 300 GMDQYFQREG RDWERYAWLK ARAVAGDIDA GEAWLETLRP FVYRRYLDFT ALDGLREMKA 310 320 330 340 350 360 AITAEVARHD RLDDIKRGPG GIREIEFLAQ SLQLIRGGRE PSLRERRLLP ALQALVAAGQ 370 380 390 400 410 420 IDQENGQALS TAYRFLRRLE NRLQMLRDAQ THALPQAPLD RERIALGLGY AQWSALLDAL 430 440 450 460 470 480 APQRARVAAE FAELLAPRVR ATAPDALADY WRALPDGDAA PLAGIGLNDP DGAHRALADF 490 500 510 520 530 540 AQSSGVRALS DSARARLDRV MPALLHAATR ASQPDAAVRR MLGLLQATLR RTSYLALLDE 550 560 570 580 590 600 QPSALARLVD VLSRSALLAE RLAAYPLLLD ELLDTRISGP LPDRAALHAA CAHTLHIDDT 610 620 630 640 650 660 EAALRELNER RLALSFRIAL ATLDGRQQAV ESTRQLAWLA EAVVQTVLHL ARSDMLAAHG 670 680 690 700 710 720 HVPGGSFAIV GYGSLGGLEL GFGSDLDLVF LYDHPREVDA SDGKRPLDAG RWFARLAQKV 730 740 750 760 770 780 MALLAAETGA GRLYDIDVRL RPDGGKGALV SSLASYREYQ RDRAWTWEHQ ALVRARAVAG 790 800 810 820 830 840 DAALCDAFAQ VRRDTLMRVR DTAQLHEDVR KMRARMRAEL DRSDAGRLDL KQGAGGLVDL 850 860 870 880 890 900 EFVLQAGVLG LAAQQPQLLD ACDTPALIDA LARTHWLPDE SAAPLHQAHA TLVDAGLSCT 910 920 930 940 LDRRPRLIAP TPAIQQARGI IFNAARGQGL TFPLGKDETA L

References

[1]

"Comparison of the genomes of two Xanthomonas pathogens with differing host specificities." da Silva A.C.R., Ferro J.A., Reinach F.C., Farah C.S., Furlan L.R., Quaggio R.B., Monteiro-Vitorello C.B., Van Sluys M.A., Almeida N.F. Jr., Alves L.M.C., do Amaral A.M., Bertolini M.C., Camargo L.E.A., Camarotte G., Cannavan F., Cardozo J., Chambergo F., Ciapina L.P. , Cicarelli R.M.B., Coutinho L.L., Cursino-Santos J.R., El-Dorry H., Faria J.B., Ferreira A.J.S., Ferreira R.C.C., Ferro M.I.T., Formighieri E.F., Franco M.C., Greggio C.C., Gruber A., Katsuyama A.M., Kishi L.T., Leite R.P., Lemos E.G.M., Lemos M.V.F., Locali E.C., Machado M.A., Madeira A.M.B.N., Martinez-Rossi N.M., Martins E.C., Meidanis J., Menck C.F.M., Miyaki C.Y., Moon D.H., Moreira L.M., Novo M.T.M., Okura V.K., Oliveira M.C., Oliveira V.R., Pereira H.A., Rossi A., Sena J.A.D., Silva C., de Souza R.F., Spinola L.A.F., Takita M.A., Tamura R.E., Teixeira E.C., Tezza R.I.D., Trindade dos Santos M., Truffi D., Tsai S.M., White F.F., Setubal J.C., Kitajima J.P. Nature 417:459-463(2002) [PubMed: 12024217] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 306.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE011682 Genomic DNA. Translation: AAM35439.1.
RefSeq	NP_640903.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1154621.
GenomeReviews	Gene locus XAC0550 in contig AE008923_GR.
KEGG	xac:XAC0550.
NMPDR	fig|190486.1.peg.547.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8PPY3.
OMA	Q8PPY3. WERYAMI.
Enzyme and pathway databases
BioCyc	XAXO190486:XAC0550-MON.
BRENDA	2.7.7.42. 289771.
Family and domain databases
HAMAP	MF_00802. [Tree]
InterPro	IPR005190. GlnE. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
Pfam	PF08335. GlnD_UR_UTase. 1 hit. PF03710. GlnE. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLNE_XANAC

Accession

Primary (citable) accession number: Q8PPY3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 4, 2005
Last sequence update:	October 1, 2002
Last modified:	June 16, 2009
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)