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Q8PNZ5 (SYQ_XANAC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine--tRNA ligase

EC=6.1.1.18
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS
Gene names
Name:glnS
Ordered Locus Names:XAC0893
OrganismXanthomonas axonopodis pv. citri (strain 306) [Complete proteome] [HAMAP]
Taxonomic identifier190486 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

Protein attributes

Sequence length579 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP-Rule MF_00126

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00126

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00126.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutaminyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

glutamyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glutamine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 579579Glutamine--tRNA ligase HAMAP-Rule MF_00126
PRO_0000195855

Regions

Motif41 – 5111"HIGH" region HAMAP-Rule MF_00126
Motif292 – 2965"KMSKS" region HAMAP-Rule MF_00126

Sites

Binding site2951ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8PNZ5 [UniParc].

Last modified October 10, 2002. Version 1.
Checksum: 0AE1F281D2B529D0

FASTA57965,872
        10         20         30         40         50         60 
MSETLATDAT APAEKKDFIR QIVREDLASG KHTVIRTRFP PEPNGYLHIG HAKAICLDFG 

        70         80         90        100        110        120 
LAAEFGGLCN LRLDDTNPAK EDPEFVVAIQ DDVRWLGYDW AQLRHASDYF QVYYLAAQKL 

       130        140        150        160        170        180 
IRDGHAFVCD LSAEQVRQYR GTLTEPGRNS PFRERSVEEN LDLFARMRAG EFPDGARTLR 

       190        200        210        220        230        240 
AKIDMASGNI NLRDPALYRI KHVEHQNTGN AWPIYPMYDF AHSLGDAVEG ITHSLCTLEF 

       250        260        270        280        290        300 
EDHRPLYDWC VDKVDLVGHP ELLQPLLDKG LPREAAKPRQ IEFSRLNINY TVMSKRKLTA 

       310        320        330        340        350        360 
LVEEQLVDGW DDPRMYTLQG LRRRGYTPAA MRLFVDRVGI SKQNSLIDFS VLEGCLREDL 

       370        380        390        400        410        420 
DAAAPRRMAV IDPLKLVLTN LPEGHTETLQ FSNHPKDDSF GTREVPFARE LWIEREDFAE 

       430        440        450        460        470        480 
VPPKGWKRLV PGGEIRLRGA GIARVDEVIK NADGEIVELR GWLDPESRPG MEGANRKVKG 

       490        500        510        520        530        540 
TIHWVSAAHA VEAEIRLYDR LFSVEKPDDE SEGKTYRDYL NPESKRNVRG YVEPSAAMAA 

       550        560        570 
PEQAFQFERT GYFVADRRDH SEATPVFNRS VTLRDTWAK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008923 Genomic DNA. Translation: AAM35781.1.
RefSeqNP_641245.1. NC_003919.1.

3D structure databases

ProteinModelPortalQ8PNZ5.
SMRQ8PNZ5. Positions 17-576.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING190486.XAC0893.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM35781; AAM35781; XAC0893.
GeneID1154964.
KEGGxac:XAC0893.
PATRIC24053726. VBIXanAxo33670_0961.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0008.
HOGENOMHOG000259232.
KOK01886.
OMAVTHSICT.
OrthoDBEOG6DRPF7.
ProtClustDBPRK05347.

Enzyme and pathway databases

BioCycXAXO190486:GH55-893-MONOMER.

Family and domain databases

Gene3D1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPMF_00126. Gln_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF50715. SSF50715. 1 hit.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYQ_XANAC
AccessionPrimary (citable) accession number: Q8PNZ5
Entry history
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: October 10, 2002
Last modified: February 19, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries