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Reviewed, UniProtKB/Swiss-Prot Q8PM31 (3HAO_XANAC)

Last modified July 13, 2010. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
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Names and originHide

Protein namesRecommended name:
3-hydroxyanthranilate 3,4-dioxygenase

EC=1.13.11.6
Alternative name(s):
3-hydroxyanthranilic acid dioxygenase
Short name=HAD
3-hydroxyanthranilate oxygenase
Short name=3-HAO
Gene names
Ordered Locus Names:XAC1603
OrganismXanthomonas axonopodis pv. citri (Citrus canker) [Complete proteome] [HAMAP]
Taxonomic identifier92829 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
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Protein attributesHide

Sequence length176 AA.
Sequence statusComplete.
Protein existenceInferred from homology.
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General annotation (Comments)Hide

Function

Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate By similarity. HAMAP MF_00825

Catalytic activity

3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde. HAMAP MF_00825

Cofactor

Binds 2 Fe2+ ions per subunit By similarity. HAMAP MF_00825

Subunit structure

Homodimer By similarity. HAMAP MF_00825

Sequence similarities

Belongs to the 3-HAO family.

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OntologiesHide

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Sequence annotation (Features)Hide

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 1761763-hydroxyanthranilate 3,4-dioxygenase HAMAP MF_00825
PRO_0000245479

Sites

Metal binding481Iron 1; catalytic By similarity
Metal binding541Iron 1; catalytic By similarity
Metal binding921Iron 1; catalytic By similarity
Metal binding1211Iron 2 By similarity
Metal binding1241Iron 2 By similarity
Metal binding1581Iron 2 By similarity
Metal binding1611Iron 2 By similarity
Binding site441Dioxygen By similarity
Binding site541Substrate By similarity
Binding site961Substrate By similarity
Binding site1061Substrate By similarity
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SequencesHide

Sequence LengthMass (Da)Tools
Q8PM31-1 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: FBDAA5A96755F310

FASTA17620,155
        10         20         30         40         50         60 
MLTPPINLHA WIEEHRHLLK PPVGNKCIQQ DGFIIMVVGG PNARTDYHYD EGPEWFFQLE 

        70         80         90        100        110        120 
GEMVLKVQDE GVARDIPIRA GEVFLLPPKV PHSPQRADGS IGLVIERERL PTEQDGLQWY 

       130        140        150        160        170 
CPQCNHKLYE AMFPLKNIET DFPPVFDRFY RSPALRTCSQ CGHLHPAPER YATVEG 

« Hide

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Cross-referencesHide

Sequence databases

EMBL
GenBank
DDBJ
AE008923 Genomic DNA. Translation: AAM36471.1.
RefSeqNP_641935.1.

3D structure databases

SMRQ8PM31. Positions 2-168.
ModBaseSearch...

Genome annotation databases

GeneID1155674.
GenomeReviewsGene locus XAC1603 in contig AE008923_GR.
KEGGxac:XAC1603.
NMPDRfig|190486.1.peg.1579.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG341987.
OMALKPPVNN.
ProtClustDBPRK13264.

Enzyme and pathway databases

BioCycXAXO190486:XAC1603-MONOMER.
BRENDA1.13.11.6. 289771.

Family and domain databases

HAMAPMF_00825. 3_HAO.
[Tree]
InterProIPR010329. 3hydroanth_dOase.
IPR011051. Cupin_RmlC_type.
[Graphical view]
PfamPF06052. 3-HAO. 1 hit.
[Graphical view]
SUPFAMSSF51182. RmlC_like_cupin. 1 hit.
TIGRFAMsTIGR03037. anthran_nbaC. 1 hit.
ProtoNetSearch...
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Entry informationHide

Entry name3HAO_XANAC
AccessionPrimary (citable) accession number: Q8PM31
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: October 1, 2002
Last modified: July 13, 2010
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)
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Relevant documentsHide

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents