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Q8PLL4 (GCH4_XANAC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
GTP cyclohydrolase FolE2

EC=3.5.4.16
Gene names
Name:folE2
Ordered Locus Names:XAC1781
OrganismXanthomonas axonopodis pv. citri (strain 306) [Complete proteome] [HAMAP]
Taxonomic identifier190486 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

Protein attributes

Sequence length305 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts GTP to 7,8-dihydroneopterin triphosphate By similarity. HAMAP-Rule MF_01527

Catalytic activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. HAMAP-Rule MF_01527

Pathway

Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. HAMAP-Rule MF_01527

Sequence similarities

Belongs to the GTP cyclohydrolase IV family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_process7,8-dihydroneopterin 3'-triphosphate biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionGTP cyclohydrolase I activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 305305GTP cyclohydrolase FolE2 HAMAP-Rule MF_01527
PRO_0000147733

Sites

Site1531May be catalytically important By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8PLL4 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 9A6F8DD1E1590F90

FASTA30533,253
        10         20         30         40         50         60 
MSPTLPDVAV TEPSTLSAPL RWVGMQDIAI PVQLETGSSQ LAARASVQVD LPRAELKGIH 

        70         80         90        100        110        120 
MSRLYRLLDT HLQQPLSPAM LSQLLQALID SHADCASRAA RLTLSFELML RTPALRSEGL 

       130        140        150        160        170        180 
SGWRAYPVHI AAQCRAGRTT IQLQIEVLYA STCPCSAALS RQLLSDAFVQ QHAGRDTLPL 

       190        200        210        220        230        240 
RDVVQWLQDH GTYATPHSQR SVAQVRVELP ADAQRLAIQQ LVGLCEQALA TPVQAAVRRP 

       250        260        270        280        290        300 
DEQAFARLNG ANLMCVEDAA RRLRKPLAEH YAAFHVAVRH LESLHAHDAV AETGSDDAVL 


GPTTM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008923 Genomic DNA. Translation: AAM36645.1.
RefSeqNP_642109.1. NC_003919.1.

3D structure databases

ProteinModelPortalQ8PLL4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING190486.XAC1781.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM36645; AAM36645; XAC1781.
GeneID1155852.
KEGGxac:XAC1781.
PATRIC24055581. VBIXanAxo33670_1865.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1469.
HOGENOMHOG000247517.
KOK09007.
OMAFCEDAAR.
OrthoDBEOG6X6RBH.
ProtClustDBPRK13674.

Enzyme and pathway databases

BioCycXAXO190486:GH55-1781-MONOMER.
UniPathwayUPA00848; UER00151.

Family and domain databases

HAMAPMF_01527_B. GTP_cyclohydrol_B.
InterProIPR022838. GTP_cyclohydrolase_FolE2.
IPR003801. GTP_cyclohydrolase_FolE2/MptA.
[Graphical view]
PfamPF02649. GCHY-1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGCH4_XANAC
AccessionPrimary (citable) accession number: Q8PLL4
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: October 1, 2002
Last modified: February 19, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways