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Q8PLB4 (CHEB1_XANAC) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon
EC=3.1.1.61
Gene names
Name:cheB1
Ordered Locus Names:XAC1888
OrganismXanthomonas axonopodis pv. citri (Citrus canker) [Complete proteome] [HAMAP]
Taxonomic identifier92829 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas

Protein attributes

Sequence length358 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR By similarity. HAMAP MF_00099

Catalytic activity

Protein L-glutamate O(5)-methyl ester + H2O = protein L-glutamate + methanol. HAMAP MF_00099

Subcellular location

Cytoplasm HAMAP MF_00099.

Domain

The N-terminal regulatory domain inhibits the activity of the C-terminal effector domain. HAMAP MF_00099

Post-translational modification

Phosphorylated by CheA. Phosphorylation suppresses the inhibitory activity of the N-terminal domain By similarity. HAMAP MF_00099

Sequence similarities

Contains 1 cheB-type methylesterase domain.

Contains 1 response regulatory domain.

Ontologies

Keywords
   Biological processChemotaxis
   Cellular componentCytoplasm
   Molecular functionHydrolase
   PTMPhosphoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processchemotaxis

Inferred from electronic annotation. Source: UniProtKB-KW

regulation of transcription, DNA-dependent

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionprotein-glutamate methylesterase activity

Inferred from electronic annotation. Source: EC

two-component response regulator activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 358358Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon HAMAP MF_00099
PRO_0000158043

Regions

Domain8 – 125118Response regulatory
Domain165 – 357193CheB-type methylesterase

Sites

Active site1771 By similarity
Active site2031 By similarity
Active site2991 By similarity

Amino acid modifications

Modified residue5914-aspartylphosphate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8PLB4 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: DDDBDF1C4E11942F

FASTA35838,028
        10         20         30         40         50         60 
MTLETPVRVL IVDDSAVVRQ MLTEILSRDA GIEVVGSAAD PLLAREKIKR LNPDVITLDV 

        70         80         90        100        110        120 
EMPRMDGLVF LENLMRLRPT PVVMISSLTE RGADTTLQAL SLGAVDFVSK PKIDVARGLE 

       130        140        150        160        170        180 
GYAEEIVSKV KMAAKAKVSA LNRPSAPKVT LDMQSAPVAG SALRFRTTDR LIAIGASAGG 

       190        200        210        220        230        240 
TEALRVVLEH MPADAPAVVM TQHLPASFST AFAERLNRHS AMSVREATDG EAILPGHAYL 

       250        260        270        280        290        300 
PPGGQHLRII RDGARWRCRI DDGPPVNRHK PAVDVLFRSV AANAGPNAVG AILTGMGDDG 

       310        320        330        340        350 
ARGLLEMLQA GAPTLVQDEA SSVVWGMPGA AYKLGAAQEV VPLDRVAERL LALSAQAR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE008923 Genomic DNA. Translation: AAM36750.1.
RefSeqNP_642214.1. NC_003919.1.

3D structure databases

ProteinModelPortalQ8PLB4.
SMRQ8PLB4. Positions 5-357.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1155959.
GenomeReviewsGene locus XAC1888 in contig AE008923_GR.
KEGGxac:XAC1888.
PATRIC24055811. VBIXanAxo33670_1978.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG705324.
OMAPPSVADF.
ProtClustDBPRK12555.

Enzyme and pathway databases

BioCycXAXO190486:XAC1888-MONOMER.

Family and domain databases

HAMAPMF_00099. CheB_methylest.
[Tree]
InterProIPR011006. CheY-like_superfamily.
IPR008248. Sig_transdc_resp-reg_CheB.
IPR000673. Sig_transdc_resp-reg_Me-estase.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
Gene3DG3DSA:3.40.50.180. Chemotax_RR_pGlu_Me-esterase. 1 hit.
KOK03412.
PfamPF01339. CheB_methylest. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
PIRSFPIRSF000876. RR_chemtxs_CheB. 1 hit.
SMARTSM00448. REC. 1 hit.
[Graphical view]
SUPFAMSSF52738. Chemotax_RR_pGlu_Me-esterase. 1 hit.
SSF52172. CheY_like. 1 hit.
PROSITEPS50122. CHEB. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCHEB1_XANAC
AccessionPrimary (citable) accession number: Q8PLB4
Entry history
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: October 1, 2002
Last modified: January 25, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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