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Protein

Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon

Gene

cheB1

Organism
Xanthomonas axonopodis pv. citri (strain 306)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR.UniRule annotation

Catalytic activityi

Protein L-glutamate O5-methyl ester + H2O = protein L-glutamate + methanol.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei177UniRule annotation1
Active sitei203UniRule annotation1
Active sitei299UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processChemotaxis

Names & Taxonomyi

Protein namesi
Recommended name:
Chemotaxis response regulator protein-glutamate methylesterase of group 1 operonUniRule annotation (EC:3.1.1.61UniRule annotation)
Gene namesi
Name:cheB1UniRule annotation
Ordered Locus Names:XAC1888
OrganismiXanthomonas axonopodis pv. citri (strain 306)
Taxonomic identifieri190486 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
Proteomesi
  • UP000000576 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001580431 – 358Chemotaxis response regulator protein-glutamate methylesterase of group 1 operonAdd BLAST358

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei594-aspartylphosphateUniRule annotation1

Post-translational modificationi

Phosphorylated by CheA. Phosphorylation suppresses the inhibitory activity of the N-terminal domain.UniRule annotation

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi190486.XAC1888.

Structurei

3D structure databases

ProteinModelPortaliQ8PLB4.
SMRiQ8PLB4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 125Response regulatoryPROSITE-ProRule annotationAdd BLAST118
Domaini165 – 357CheB-type methylesteraseUniRule annotationAdd BLAST193

Domaini

The N-terminal regulatory domain inhibits the activity of the C-terminal effector domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CMP. Bacteria.
COG2201. LUCA.
HOGENOMiHOG000151424.
KOiK03412.
OMAiAMVKIRQ.
OrthoDBiPOG091H045J.

Family and domain databases

CDDicd16432. CheB_Rec. 1 hit.
cd00156. REC. 1 hit.
Gene3Di3.40.50.180. 1 hit.
HAMAPiMF_00099. CheB_methylest. 1 hit.
InterProiView protein in InterPro
IPR035909. CheB_C.
IPR011006. CheY-like_superfamily.
IPR008248. Sig_transdc_resp-reg_CheB.
IPR000673. Sig_transdc_resp-reg_Me-estase.
IPR001789. Sig_transdc_resp-reg_receiver.
PfamiView protein in Pfam
PF01339. CheB_methylest. 1 hit.
PF00072. Response_reg. 1 hit.
PIRSFiPIRSF000876. RR_chemtxs_CheB. 1 hit.
SMARTiView protein in SMART
SM00448. REC. 1 hit.
SUPFAMiSSF52172. SSF52172. 1 hit.
SSF52738. SSF52738. 1 hit.
PROSITEiView protein in PROSITE
PS50122. CHEB. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8PLB4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLETPVRVL IVDDSAVVRQ MLTEILSRDA GIEVVGSAAD PLLAREKIKR
60 70 80 90 100
LNPDVITLDV EMPRMDGLVF LENLMRLRPT PVVMISSLTE RGADTTLQAL
110 120 130 140 150
SLGAVDFVSK PKIDVARGLE GYAEEIVSKV KMAAKAKVSA LNRPSAPKVT
160 170 180 190 200
LDMQSAPVAG SALRFRTTDR LIAIGASAGG TEALRVVLEH MPADAPAVVM
210 220 230 240 250
TQHLPASFST AFAERLNRHS AMSVREATDG EAILPGHAYL PPGGQHLRII
260 270 280 290 300
RDGARWRCRI DDGPPVNRHK PAVDVLFRSV AANAGPNAVG AILTGMGDDG
310 320 330 340 350
ARGLLEMLQA GAPTLVQDEA SSVVWGMPGA AYKLGAAQEV VPLDRVAERL

LALSAQAR
Length:358
Mass (Da):38,028
Last modified:October 1, 2002 - v1
Checksum:iDDDBDF1C4E11942F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008923 Genomic DNA. Translation: AAM36750.1.
RefSeqiWP_003486327.1. NC_003919.1.

Genome annotation databases

EnsemblBacteriaiAAM36750; AAM36750; XAC1888.
GeneIDi34206659.
KEGGixac:XAC1888.

Similar proteinsi

Entry informationi

Entry nameiCHEB1_XANAC
AccessioniPrimary (citable) accession number: Q8PLB4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: October 1, 2002
Last modified: November 22, 2017
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome