Reviewed, UniProtKB/Swiss-Prot Q8PKU2 (GLK_XANAC)

Names and origin

Protein names

Recommended name:
    Glucokinase
    EC=2.7.1.2
Alternative name(s):
    Glucose kinase

Gene names

Name:	glk
Ordered Locus Names:	XAC2070

Organism

Xanthomonas axonopodis pv. citri (Citrus canker) [Complete proteome] [HAMAP]

Taxonomic identifier

92829 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas

Protein attributes

Sequence length	335 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP MF_00524
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the bacterial glucokinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glucokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 335	335	Glucokinase HAMAP MF_00524		PRO_0000215141
Regions
	Nucleotide binding	11 – 16	6	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8PKU2-1 [UniParc]. Last modified October 10, 2002. Version 1. Checksum: 008342BA29B2D837	FASTA	335	35,518
	10 20 30 40 50 60 MTAPSKPVLV ADIGGTNARF ALADVDASVP LLDDTSREFA VVDFGSLGEA ARYYLDQIGV 70 80 90 100 110 120 QATQGVFAVA GRVDGDEARI TNHPWVISRS RTATMLGFST LHLINDFAAQ AMAISLLRPQ 130 140 150 160 170 180 DVVQVGGASW RPAPIDQARN YGVIGPGTGL GVGGLIIRNG RCFPLETEGG HVSFPPGTPE 190 200 210 220 230 240 EIRILEILSE QFGRVSNERL ICGPGLVNIH RALSEIAGVD PGPLQPKDIT ARAAAGDPRS 250 260 270 280 290 300 SRTIDLFCAI FGAIAGDMVL MQGAWDGVFL TGGLVPKVLD SLQHSGFRQR FEHKGRFSAI 310 320 330 MSKVPSLAVM HPHAGLLGAA AYAVDAQRQH PGEQR

References

[1]

"Comparison of the genomes of two Xanthomonas pathogens with differing host specificities." da Silva A.C.R., Ferro J.A., Reinach F.C., Farah C.S., Furlan L.R., Quaggio R.B., Monteiro-Vitorello C.B., Van Sluys M.A., Almeida N.F. Jr., Alves L.M.C., do Amaral A.M., Bertolini M.C., Camargo L.E.A., Camarotte G., Cannavan F., Cardozo J., Chambergo F., Ciapina L.P. , Cicarelli R.M.B., Coutinho L.L., Cursino-Santos J.R., El-Dorry H., Faria J.B., Ferreira A.J.S., Ferreira R.C.C., Ferro M.I.T., Formighieri E.F., Franco M.C., Greggio C.C., Gruber A., Katsuyama A.M., Kishi L.T., Leite R.P., Lemos E.G.M., Lemos M.V.F., Locali E.C., Machado M.A., Madeira A.M.B.N., Martinez-Rossi N.M., Martins E.C., Meidanis J., Menck C.F.M., Miyaki C.Y., Moon D.H., Moreira L.M., Novo M.T.M., Okura V.K., Oliveira M.C., Oliveira V.R., Pereira H.A., Rossi A., Sena J.A.D., Silva C., de Souza R.F., Spinola L.A.F., Takita M.A., Tamura R.E., Teixeira E.C., Tezza R.I.D., Trindade dos Santos M., Truffi D., Tsai S.M., White F.F., Setubal J.C., Kitajima J.P. Nature 417:459-463(2002) [PubMed: 12024217] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 306.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE011843 Genomic DNA. Translation: AAM36927.1.
RefSeq	NP_642391.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1156141.
GenomeReviews	Gene locus XAC2070 in contig AE008923_GR.
KEGG	xac:XAC2070.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8PKU2.
OMA	Q8PKU2. VDIGGTH.
Enzyme and pathway databases
BioCyc	XAXO190486:XAC2070-MON.
BRENDA	2.7.1.2. 289771.
Family and domain databases
HAMAP	MF_00524. [Tree]
InterPro	IPR003836. Glucokinase. [Graphical view]
Pfam	PF02685. Glucokinase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00749. glk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLK_XANAC

Accession

Primary (citable) accession number: Q8PKU2

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 10, 2002
Last sequence update:	October 10, 2002
Last modified:	June 16, 2009
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)