Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chemotaxis response regulator protein-glutamate methylesterase of group 2 operon

Gene

cheB2

Organism
Xanthomonas axonopodis pv. citri (strain 306)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR.UniRule annotation

Catalytic activityi

Protein L-glutamate O5-methyl ester + H2O = protein L-glutamate + methanol.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei174UniRule annotation1
Active sitei200UniRule annotation1
Active sitei296UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processChemotaxis

Names & Taxonomyi

Protein namesi
Recommended name:
Chemotaxis response regulator protein-glutamate methylesterase of group 2 operonUniRule annotation (EC:3.1.1.61UniRule annotation)
Gene namesi
Name:cheB2UniRule annotation
Ordered Locus Names:XAC2870
OrganismiXanthomonas axonopodis pv. citri (strain 306)
Taxonomic identifieri190486 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
Proteomesi
  • UP000000576 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001580441 – 352Chemotaxis response regulator protein-glutamate methylesterase of group 2 operonAdd BLAST352

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei504-aspartylphosphateUniRule annotation1

Post-translational modificationi

Phosphorylated by CheA. Phosphorylation suppresses the inhibitory activity of the N-terminal domain.UniRule annotation

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi190486.XAC2870.

Structurei

3D structure databases

ProteinModelPortaliQ8PIM5.
SMRiQ8PIM5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 116Response regulatoryPROSITE-ProRule annotationAdd BLAST116
Domaini162 – 352CheB-type methylesteraseUniRule annotationAdd BLAST191

Domaini

The N-terminal regulatory domain inhibits the activity of the C-terminal effector domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CMP. Bacteria.
COG2201. LUCA.
HOGENOMiHOG000151423.
KOiK03412.
OMAiHAMAQTT.
OrthoDBiPOG091H045J.

Family and domain databases

CDDicd16432. CheB_Rec. 1 hit.
cd00156. REC. 1 hit.
Gene3Di3.40.50.180. 1 hit.
HAMAPiMF_00099. CheB_methylest. 1 hit.
InterProiView protein in InterPro
IPR035909. CheB_C.
IPR011006. CheY-like_superfamily.
IPR008248. Sig_transdc_resp-reg_CheB.
IPR000673. Sig_transdc_resp-reg_Me-estase.
IPR001789. Sig_transdc_resp-reg_receiver.
PfamiView protein in Pfam
PF01339. CheB_methylest. 1 hit.
PF00072. Response_reg. 1 hit.
PIRSFiPIRSF000876. RR_chemtxs_CheB. 1 hit.
SMARTiView protein in SMART
SM00448. REC. 1 hit.
SUPFAMiSSF52172. SSF52172. 1 hit.
SSF52738. SSF52738. 1 hit.
PROSITEiView protein in PROSITE
PS50122. CHEB. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8PIM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVDDSAVVR QVLVGVLNDA PGIDVIATAA DPLLAIEKMR QHWPDVIVLD
60 70 80 90 100
VEMPRMDGIT FLRKIMSERP TPVVICSTLT EKGARVTMDA LAAGAVAVVT
110 120 130 140 150
KPRLGLKQFL TDSADELVAT VRSAARANVK RLAARVTAAP LEAEVKHTAD
160 170 180 190 200
VILPAQSGRA LAQTTERIVA IGTSTGGTQA LEEVLTALPR VCPGIVIVQH
210 220 230 240 250
MPEKFTAAFA ARLNGLCQIA VKEAANNDRV MPGRALIAPG GKHLLLRRSG
260 270 280 290 300
AQYFVEVLEG PPVNRHRPSV DVLFRSAARA AGSNALGIIM TGMGDDGAAG
310 320 330 340 350
LLEMRQAGAR TVAQDEHTSI VFGMPKEAIK RGGADRILPL GAMAREIVTQ

LQ
Length:352
Mass (Da):37,250
Last modified:October 1, 2002 - v1
Checksum:iF4B08C1BC3320982
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008923 Genomic DNA. Translation: AAM37715.1.

Genome annotation databases

EnsemblBacteriaiAAM37715; AAM37715; XAC2870.
KEGGixac:XAC2870.

Similar proteinsi

Entry informationi

Entry nameiCHEB2_XANAC
AccessioniPrimary (citable) accession number: Q8PIM5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: October 1, 2002
Last modified: November 22, 2017
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome