Q8PET9 (UXAC_XANAC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uronate isomerase
EC=5.3.1.12

Alternative name(s):
Glucuronate isomerase
Uronic isomerase

Gene names

Name:	uxaC
Synonyms:	hrmI
Ordered Locus Names:	XAC4251

Organism

Xanthomonas axonopodis pv. citri (strain 306) [Complete proteome] [HAMAP]

Taxonomic identifier

190486 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas › Xanthomonas citri group › Xanthomonas campestris pv. citri › Xanthomonas citri pv. citri

Protein attributes

Sequence length	472 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucuronate = D-fructuronate. HAMAP-Rule MF_00675 D-galacturonate = D-tagaturonate. HAMAP-Rule MF_00675
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP-Rule MF_00675
Sequence similarities	Belongs to the uronate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glucuronate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	glucuronate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 472	472	Uronate isomerase HAMAP-Rule MF_00675		PRO_0000172794

Sequences

	Sequence		Length	Mass (Da)
	Q8PET9 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 8F59D75349D217CC	FASTA	472	52,896
	10 20 30 40 50 60 MRSSVLSLHP DRLLPADPGT RAIARRLYAQ VATLPIISPH GHTDPAWFAT NAPFANATEL 70 80 90 100 110 120 LLVPDHYVFR MLYSQGIDLD ALGIPRADGT RATVDPRAAW RVFAEHYTLL RGTPSALWLN 130 140 150 160 170 180 HVFHDVFDLR IRLDAGTADH YYDHITAALQ TPAFLPRALF ERFNIEVIAT TESPLDRLQH 190 200 210 220 230 240 HAAIAASGWQ GRVVTAYRPD PVVDPEHEQF AGALQQFGAL TGEDVLTWDG YLRAHRQRRA 250 260 270 280 290 300 FFAAHGATST DHGHPSAATA DLSPAEAQRL FDTVVRGAAT PEQAELFRAQ VLTEMAAMSL 310 320 330 340 350 360 DDGLVMQLHP GCFRNHNRQL FEQYGRDKGA DIPMRTDYVH ALKPLLDRHG NDPRLRLIVF 370 380 390 400 410 420 TLDETSYSRE LAPLAGHYPS LLLGPAWWFH DAPEGMWRFR EQTLASAGFY NTVGFNDDTR 430 440 450 460 470 AFLSIPARHD VARRVDSAFL AKLVAEHRLE EDEATEVAID LAYRLPKQAY KL

References

[1]

"Comparison of the genomes of two Xanthomonas pathogens with differing host specificities." da Silva A.C.R., Ferro J.A., Reinach F.C., Farah C.S., Furlan L.R., Quaggio R.B., Monteiro-Vitorello C.B., Van Sluys M.A., Almeida N.F. Jr., Alves L.M.C., do Amaral A.M., Bertolini M.C., Camargo L.E.A., Camarotte G., Cannavan F., Cardozo J., Chambergo F., Ciapina L.P. , Cicarelli R.M.B., Coutinho L.L., Cursino-Santos J.R., El-Dorry H., Faria J.B., Ferreira A.J.S., Ferreira R.C.C., Ferro M.I.T., Formighieri E.F., Franco M.C., Greggio C.C., Gruber A., Katsuyama A.M., Kishi L.T., Leite R.P., Lemos E.G.M., Lemos M.V.F., Locali E.C., Machado M.A., Madeira A.M.B.N., Martinez-Rossi N.M., Martins E.C., Meidanis J., Menck C.F.M., Miyaki C.Y., Moon D.H., Moreira L.M., Novo M.T.M., Okura V.K., Oliveira M.C., Oliveira V.R., Pereira H.A., Rossi A., Sena J.A.D., Silva C., de Souza R.F., Spinola L.A.F., Takita M.A., Tamura R.E., Teixeira E.C., Tezza R.I.D., Trindade dos Santos M., Truffi D., Tsai S.M., White F.F., Setubal J.C., Kitajima J.P. Nature 417:459-463(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 306.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008923 Genomic DNA. Translation: AAM39086.1.
RefSeq	NP_644550.1. NC_003919.1.
3D structure databases
ProteinModelPortal	Q8PET9.
SMR	Q8PET9. Positions 6-472.
ModBase	Search...
Protein-protein interaction databases
STRING	190486.XAC4251.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAM39086; AAM39086; XAC4251.
GeneID	1158322.
KEGG	xac:XAC4251.
PATRIC	24060704. VBIXanAxo33670_4395.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1904.
HOGENOM	HOG000238114.
KO	K01812.
OMA	GNPIYHW.
ProtClustDB	PRK02925.
Enzyme and pathway databases
UniPathway	UPA00246.
Family and domain databases
Gene3D	1.10.2020.10. 1 hit.
HAMAP	MF_00675. UxaC.
InterPro	IPR003766. Uronate_isomerase. IPR023177. Uronate_isomerase_dom2. [Graphical view]
Pfam	PF02614. UxaC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UXAC_XANAC

Accession

Primary (citable) accession number: Q8PET9

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 11, 2003
Last sequence update:	October 1, 2002
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program