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Q8PDZ9 (UPPP_XANCP) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Synonyms:bacA, upk
Ordered Locus Names:XCC0184
OrganismXanthomonas campestris pv. campestris (strain ATCC 33913 / NCPPB 528 / LMG 568) [Reference proteome] [HAMAP]
Taxonomic identifier190485 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

Protein attributes

Sequence length263 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 263263Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000151242

Regions

Transmembrane38 – 5821Helical; Potential
Transmembrane75 – 9521Helical; Potential
Transmembrane108 – 12821Helical; Potential
Transmembrane135 – 15521Helical; Potential
Transmembrane181 – 20121Helical; Potential
Transmembrane217 – 23721Helical; Potential
Transmembrane242 – 26221Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q8PDZ9 [UniParc].

Last modified October 10, 2002. Version 1.
Checksum: B81226D633C26263

FASTA26328,364
        10         20         30         40         50         60 
MSDLISALLL GILEGLTEFL PISSTGHLLI AEQWLGRRSD FFNIVIQAGA ILAICLALRQ 

        70         80         90        100        110        120 
KLWTLATGLG ERANRDYVLK IGVAFLVTAV VGLIVRKAGW QLPETIQPVA WALLIGGVWM 

       130        140        150        160        170        180 
LVAEHFAGKL PERDVVTWKV AIAVGLAQVV AGVFPGTSRS ASAIFLAMLL GLSKRSAAAD 

       190        200        210        220        230        240 
FVFMVGIPTM FAASGYALLE MYKEGGFGSE NWTDVSVAFI AATLTGFVVV KWLLGYIKKH 

       250        260 
RFTVFAVYRI LLGAALLLWL PAA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008922 Genomic DNA. Translation: AAM39503.1.
RefSeqNP_635579.1. NC_003902.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING190485.XCC0184.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM39503; AAM39503; XCC0184.
GeneID1001993.
KEGGxcc:XCC0184.
PATRIC24070941. VBIXanCam115730_0208.

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAFNDAHAK.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycXCAM190485:GIXZ-184-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP_XANCP
AccessionPrimary (citable) accession number: Q8PDZ9
Entry history
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: October 10, 2002
Last modified: May 14, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families