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Q8PCY1

- GLMS_XANCP

UniProt

Q8PCY1 - GLMS_XANCP

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Protein

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

Gene

glmS

Organism
Xanthomonas campestris pv. campestris (strain ATCC 33913 / NCPPB 528 / LMG 568)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei2 – 21Nucleophile; for GATase activityUniRule annotation
Active sitei604 – 6041For Fru-6P isomerization activityUniRule annotation

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate biosynthetic process Source: InterPro
  2. glutamine metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Enzyme and pathway databases

BioCyciXCAM190485:GIXZ-569-MONOMER.

Protein family/group databases

MEROPSiC44.971.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation (EC:2.6.1.16UniRule annotation)
Alternative name(s):
D-fructose-6-phosphate amidotransferaseUniRule annotation
GFATUniRule annotation
Glucosamine-6-phosphate synthaseUniRule annotation
Hexosephosphate aminotransferaseUniRule annotation
L-glutamine--D-fructose-6-phosphate amidotransferaseUniRule annotation
Gene namesi
Name:glmSUniRule annotation
Ordered Locus Names:XCC0569
OrganismiXanthomonas campestris pv. campestris (strain ATCC 33913 / NCPPB 528 / LMG 568)
Taxonomic identifieri190485 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
ProteomesiUP000001010: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedUniRule annotation
Chaini2 – 609608Glutamine--fructose-6-phosphate aminotransferase [isomerizing]PRO_0000135415Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi190485.XCC0569.

Structurei

3D structure databases

ProteinModelPortaliQ8PCY1.
SMRiQ8PCY1. Positions 2-609.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 217216Glutamine amidotransferase type-2UniRule annotationAdd
BLAST
Domaini284 – 425142SIS 1UniRule annotationAdd
BLAST
Domaini458 – 599142SIS 2UniRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 glutamine amidotransferase type-2 domain.UniRule annotation
Contains 2 SIS domains.UniRule annotation

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

eggNOGiCOG0449.
HOGENOMiHOG000258896.
KOiK00820.
OMAiHIINTLA.
OrthoDBiEOG6KT2Q1.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
HAMAPiMF_00164. GlmS.
InterProiIPR017932. GATase_2_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view]
PANTHERiPTHR10937:SF0. PTHR10937:SF0. 1 hit.
PfamiPF01380. SIS. 2 hits.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01135. glmS. 1 hit.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8PCY1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MCGIVGAIAG RDVVPVLIEG LKRLEYRGYD SSGIAVLDGT QVRRVRRTGR
60 70 80 90 100
VAEMAQAAQA EQFGATLGIG HTRWATHGGV TEANAHPHIS AGVALVHNGI
110 120 130 140 150
IENHEEQREK LRALGYTFES QTDTEVIAHL IHHHLADAGD LLSALQRTVK
160 170 180 190 200
ELTGAYALAV MSQAEQERFV CARMGCPLLI GVGEGENFVA SDVSAIVQAT
210 220 230 240 250
RQVIFLEEGD TAELRRDGVR VFDASDAAVE RPLHLSDVSL ASLELGPFRH
260 270 280 290 300
FMQKEIHEQP RALADTIEAA IDAKGFPASL FGPTADAVLR DIEGVQILAC
310 320 330 340 350
GTSYYAGLTA RYWIEAIAGL PCSVEIASEY RYRAAYANPK HLIVTISQSG
360 370 380 390 400
ETLDTMEALK YAKSLGHLHT LSICNVPESA IPRASELVCY TRAGAEIGVA
410 420 430 440 450
STKAFTTQLA VLFQLTMVLG KLQGRISDSE EADYLEQLRF LPGSVQHALN
460 470 480 490 500
LEPQIMAWAE RFSPKENALF LGRGLHYPIA LEGALKLKEI SYIHAEAYPA
510 520 530 540 550
GELKHGPLAL VDATMPVVVI APNDRLLEKV KSNMQEVRAR GGELFVFADQ
560 570 580 590 600
DSHFSESDGV HVIRTPRHAG VLSPVIHTIP VQLLAYHTAL ARGTDVDKPR

NLAKSVTVE
Length:609
Mass (Da):66,094
Last modified:January 23, 2007 - v2
Checksum:i9E88C6881020F490
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008922 Genomic DNA. Translation: AAM39885.1.
RefSeqiNP_635961.1. NC_003902.1.

Genome annotation databases

EnsemblBacteriaiAAM39885; AAM39885; XCC0569.
GeneIDi1001073.
KEGGixcc:XCC0569.
PATRICi24071781. VBIXanCam115730_0626.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008922 Genomic DNA. Translation: AAM39885.1 .
RefSeqi NP_635961.1. NC_003902.1.

3D structure databases

ProteinModelPortali Q8PCY1.
SMRi Q8PCY1. Positions 2-609.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 190485.XCC0569.

Protein family/group databases

MEROPSi C44.971.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM39885 ; AAM39885 ; XCC0569 .
GeneIDi 1001073.
KEGGi xcc:XCC0569.
PATRICi 24071781. VBIXanCam115730_0626.

Phylogenomic databases

eggNOGi COG0449.
HOGENOMi HOG000258896.
KOi K00820.
OMAi HIINTLA.
OrthoDBi EOG6KT2Q1.

Enzyme and pathway databases

BioCyci XCAM190485:GIXZ-569-MONOMER.

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
HAMAPi MF_00164. GlmS.
InterProi IPR017932. GATase_2_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view ]
PANTHERi PTHR10937:SF0. PTHR10937:SF0. 1 hit.
Pfami PF01380. SIS. 2 hits.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
TIGRFAMsi TIGR01135. glmS. 1 hit.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view ]
ProtoNeti Search...

Entry informationi

Entry nameiGLMS_XANCP
AccessioniPrimary (citable) accession number: Q8PCY1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3