Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

Gene

glmS

Organism
Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei2Nucleophile; for GATase activityUniRule annotation1
Active sitei604For Fru-6P isomerization activityUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferase, Transferase

Enzyme and pathway databases

BioCyciXCAM190485:G1FZM-569-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation (EC:2.6.1.16UniRule annotation)
Alternative name(s):
D-fructose-6-phosphate amidotransferaseUniRule annotation
GFATUniRule annotation
Glucosamine-6-phosphate synthaseUniRule annotation
Hexosephosphate aminotransferaseUniRule annotation
L-glutamine--D-fructose-6-phosphate amidotransferaseUniRule annotation
Gene namesi
Name:glmSUniRule annotation
Ordered Locus Names:XCC0569
OrganismiXanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Taxonomic identifieri190485 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
Proteomesi

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedUniRule annotation
ChainiPRO_00001354152 – 609Glutamine--fructose-6-phosphate aminotransferase [isomerizing]Add BLAST608

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi190485.XCC0569

Structurei

3D structure databases

ProteinModelPortaliQ8PCY1
SMRiQ8PCY1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 217Glutamine amidotransferase type-2UniRule annotationAdd BLAST216
Domaini284 – 425SIS 1UniRule annotationAdd BLAST142
Domaini458 – 599SIS 2UniRule annotationAdd BLAST142

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

eggNOGiENOG4105C46 Bacteria
COG0449 LUCA
HOGENOMiHOG000258896
KOiK00820
OMAiGTSHYAG

Family and domain databases

CDDicd05008 SIS_GlmS_GlmD_1, 1 hit
cd05009 SIS_GlmS_GlmD_2, 1 hit
Gene3Di3.60.20.10, 1 hit
HAMAPiMF_00164 GlmS, 1 hit
InterProiView protein in InterPro
IPR017932 GATase_2_dom
IPR035466 GlmS/AgaS_SIS
IPR035490 GlmS/FrlB_SIS
IPR005855 GlmS_trans
IPR029055 Ntn_hydrolases_N
IPR001347 SIS
PANTHERiPTHR10937:SF0 PTHR10937:SF0, 1 hit
PfamiView protein in Pfam
PF01380 SIS, 2 hits
SUPFAMiSSF56235 SSF56235, 1 hit
TIGRFAMsiTIGR01135 glmS, 1 hit
PROSITEiView protein in PROSITE
PS51278 GATASE_TYPE_2, 1 hit
PS51464 SIS, 2 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8PCY1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCGIVGAIAG RDVVPVLIEG LKRLEYRGYD SSGIAVLDGT QVRRVRRTGR
60 70 80 90 100
VAEMAQAAQA EQFGATLGIG HTRWATHGGV TEANAHPHIS AGVALVHNGI
110 120 130 140 150
IENHEEQREK LRALGYTFES QTDTEVIAHL IHHHLADAGD LLSALQRTVK
160 170 180 190 200
ELTGAYALAV MSQAEQERFV CARMGCPLLI GVGEGENFVA SDVSAIVQAT
210 220 230 240 250
RQVIFLEEGD TAELRRDGVR VFDASDAAVE RPLHLSDVSL ASLELGPFRH
260 270 280 290 300
FMQKEIHEQP RALADTIEAA IDAKGFPASL FGPTADAVLR DIEGVQILAC
310 320 330 340 350
GTSYYAGLTA RYWIEAIAGL PCSVEIASEY RYRAAYANPK HLIVTISQSG
360 370 380 390 400
ETLDTMEALK YAKSLGHLHT LSICNVPESA IPRASELVCY TRAGAEIGVA
410 420 430 440 450
STKAFTTQLA VLFQLTMVLG KLQGRISDSE EADYLEQLRF LPGSVQHALN
460 470 480 490 500
LEPQIMAWAE RFSPKENALF LGRGLHYPIA LEGALKLKEI SYIHAEAYPA
510 520 530 540 550
GELKHGPLAL VDATMPVVVI APNDRLLEKV KSNMQEVRAR GGELFVFADQ
560 570 580 590 600
DSHFSESDGV HVIRTPRHAG VLSPVIHTIP VQLLAYHTAL ARGTDVDKPR

NLAKSVTVE
Length:609
Mass (Da):66,094
Last modified:January 23, 2007 - v2
Checksum:i9E88C6881020F490
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008922 Genomic DNA Translation: AAM39885.1
RefSeqiNP_635961.1, NC_003902.1
WP_011035815.1, NC_003902.1

Genome annotation databases

EnsemblBacteriaiAAM39885; AAM39885; XCC0569
GeneIDi1001073
35544635
KEGGixcc:XCC0569
PATRICifig|190485.4.peg.626

Similar proteinsi

Entry informationi

Entry nameiGLMS_XANCP
AccessioniPrimary (citable) accession number: Q8PCY1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 101 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health