Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8PCY1

- GLMS_XANCP

UniProt

Q8PCY1 - GLMS_XANCP

Protein

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

Gene

glmS

Organism
Xanthomonas campestris pv. campestris (strain ATCC 33913 / NCPPB 528 / LMG 568)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 2 (23 Jan 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.UniRule annotation

    Catalytic activityi

    L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei2 – 21Nucleophile; for GATase activityUniRule annotation
    Active sitei604 – 6041For Fru-6P isomerization activityUniRule annotation

    GO - Molecular functioni

    1. carbohydrate binding Source: InterPro
    2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbohydrate biosynthetic process Source: InterPro
    2. glutamine metabolic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Aminotransferase, Transferase

    Enzyme and pathway databases

    BioCyciXCAM190485:GIXZ-569-MONOMER.

    Protein family/group databases

    MEROPSiC44.971.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation (EC:2.6.1.16UniRule annotation)
    Alternative name(s):
    D-fructose-6-phosphate amidotransferaseUniRule annotation
    GFATUniRule annotation
    Glucosamine-6-phosphate synthaseUniRule annotation
    Hexosephosphate aminotransferaseUniRule annotation
    L-glutamine--D-fructose-6-phosphate amidotransferaseUniRule annotation
    Gene namesi
    Name:glmSUniRule annotation
    Ordered Locus Names:XCC0569
    OrganismiXanthomonas campestris pv. campestris (strain ATCC 33913 / NCPPB 528 / LMG 568)
    Taxonomic identifieri190485 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
    ProteomesiUP000001010: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedUniRule annotation
    Chaini2 – 609608Glutamine--fructose-6-phosphate aminotransferase [isomerizing]PRO_0000135415Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi190485.XCC0569.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8PCY1.
    SMRiQ8PCY1. Positions 2-609.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini2 – 217216Glutamine amidotransferase type-2UniRule annotationAdd
    BLAST
    Domaini284 – 425142SIS 1UniRule annotationAdd
    BLAST
    Domaini458 – 599142SIS 2UniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 glutamine amidotransferase type-2 domain.UniRule annotation
    Contains 2 SIS domains.UniRule annotation

    Keywords - Domaini

    Glutamine amidotransferase, Repeat

    Phylogenomic databases

    eggNOGiCOG0449.
    HOGENOMiHOG000258896.
    KOiK00820.
    OMAiHIINTLA.
    OrthoDBiEOG6KT2Q1.

    Family and domain databases

    Gene3Di3.60.20.10. 1 hit.
    HAMAPiMF_00164. GlmS.
    InterProiIPR017932. GATase_2_dom.
    IPR005855. GlmS_trans.
    IPR029055. Ntn_hydrolases_N.
    IPR001347. SIS.
    [Graphical view]
    PANTHERiPTHR10937:SF0. PTHR10937:SF0. 1 hit.
    PfamiPF01380. SIS. 2 hits.
    [Graphical view]
    SUPFAMiSSF56235. SSF56235. 1 hit.
    TIGRFAMsiTIGR01135. glmS. 1 hit.
    PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
    PS51464. SIS. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8PCY1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MCGIVGAIAG RDVVPVLIEG LKRLEYRGYD SSGIAVLDGT QVRRVRRTGR    50
    VAEMAQAAQA EQFGATLGIG HTRWATHGGV TEANAHPHIS AGVALVHNGI 100
    IENHEEQREK LRALGYTFES QTDTEVIAHL IHHHLADAGD LLSALQRTVK 150
    ELTGAYALAV MSQAEQERFV CARMGCPLLI GVGEGENFVA SDVSAIVQAT 200
    RQVIFLEEGD TAELRRDGVR VFDASDAAVE RPLHLSDVSL ASLELGPFRH 250
    FMQKEIHEQP RALADTIEAA IDAKGFPASL FGPTADAVLR DIEGVQILAC 300
    GTSYYAGLTA RYWIEAIAGL PCSVEIASEY RYRAAYANPK HLIVTISQSG 350
    ETLDTMEALK YAKSLGHLHT LSICNVPESA IPRASELVCY TRAGAEIGVA 400
    STKAFTTQLA VLFQLTMVLG KLQGRISDSE EADYLEQLRF LPGSVQHALN 450
    LEPQIMAWAE RFSPKENALF LGRGLHYPIA LEGALKLKEI SYIHAEAYPA 500
    GELKHGPLAL VDATMPVVVI APNDRLLEKV KSNMQEVRAR GGELFVFADQ 550
    DSHFSESDGV HVIRTPRHAG VLSPVIHTIP VQLLAYHTAL ARGTDVDKPR 600
    NLAKSVTVE 609
    Length:609
    Mass (Da):66,094
    Last modified:January 23, 2007 - v2
    Checksum:i9E88C6881020F490
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008922 Genomic DNA. Translation: AAM39885.1.
    RefSeqiNP_635961.1. NC_003902.1.

    Genome annotation databases

    EnsemblBacteriaiAAM39885; AAM39885; XCC0569.
    GeneIDi1001073.
    KEGGixcc:XCC0569.
    PATRICi24071781. VBIXanCam115730_0626.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008922 Genomic DNA. Translation: AAM39885.1 .
    RefSeqi NP_635961.1. NC_003902.1.

    3D structure databases

    ProteinModelPortali Q8PCY1.
    SMRi Q8PCY1. Positions 2-609.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 190485.XCC0569.

    Protein family/group databases

    MEROPSi C44.971.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM39885 ; AAM39885 ; XCC0569 .
    GeneIDi 1001073.
    KEGGi xcc:XCC0569.
    PATRICi 24071781. VBIXanCam115730_0626.

    Phylogenomic databases

    eggNOGi COG0449.
    HOGENOMi HOG000258896.
    KOi K00820.
    OMAi HIINTLA.
    OrthoDBi EOG6KT2Q1.

    Enzyme and pathway databases

    BioCyci XCAM190485:GIXZ-569-MONOMER.

    Family and domain databases

    Gene3Di 3.60.20.10. 1 hit.
    HAMAPi MF_00164. GlmS.
    InterProi IPR017932. GATase_2_dom.
    IPR005855. GlmS_trans.
    IPR029055. Ntn_hydrolases_N.
    IPR001347. SIS.
    [Graphical view ]
    PANTHERi PTHR10937:SF0. PTHR10937:SF0. 1 hit.
    Pfami PF01380. SIS. 2 hits.
    [Graphical view ]
    SUPFAMi SSF56235. SSF56235. 1 hit.
    TIGRFAMsi TIGR01135. glmS. 1 hit.
    PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
    PS51464. SIS. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Entry informationi

    Entry nameiGLMS_XANCP
    AccessioniPrimary (citable) accession number: Q8PCY1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 10, 2002
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 81 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3