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Q8PCP3

- PNCB_XANCP

UniProt

Q8PCP3 - PNCB_XANCP

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Protein
Nicotinate phosphoribosyltransferase
Gene
pncB, XCC0681
Organism
Xanthomonas campestris pv. campestris (strain ATCC 33913 / NCPPB 528 / LMG 568)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate phosphoribosyltransferase activity Source: InterPro
  3. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciXCAM190485:GIXZ-680-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferase (EC:6.3.4.21)
Short name:
NAPRTase
Gene namesi
Name:pncB
Ordered Locus Names:XCC0681
OrganismiXanthomonas campestris pv. campestris (strain ATCC 33913 / NCPPB 528 / LMG 568)
Taxonomic identifieri190485 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
ProteomesiUP000001010: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 398398Nicotinate phosphoribosyltransferaseUniRule annotation
PRO_0000205852Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi190485.XCC0681.

Structurei

3D structure databases

ProteinModelPortaliQ8PCP3.

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284928.
KOiK00763.
OMAiQAVFHRY.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8PCP3-1 [UniParc]FASTAAdd to Basket

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MIIHSLLDTD LYKFTMMQAV LHQHPAAQVD YRFKCRTPGV DLAQFIDEIS    50
REIDALCRLR LREDEVDYLR SLRFIKPDFA DFLALFHLDR KYLALAASAA 100
HPGEIELTIR GPWLHTILFE VPLLAIINEV WFRNTSEPDF EEGRSRLREK 150
VRSLRSMPAG CKIADYGTRR RYSRQWHGEL LPLLRDGLGE QFVGTSNVFF 200
AKQYGLTPLG TMAHEYLQAF QALGPRLRDS QVAALDSWAR EYRGDLGIAL 250
SDVVGLDAFL RDFDLYFCKL FDGMRHDSGD PFDWGERVIA HLEAHRVDPR 300
TKVLVFSDGL NIDKVMRLYE HFSPRCRLAF GVGTSLTNDL GPTPLQIVIK 350
MVRCNGQPVA KLSDSPGKSM CEDLGYLRYL RDVFGLPPMP EAGDPARQ 398
Length:398
Mass (Da):45,452
Last modified:October 10, 2002 - v1
Checksum:iB32734C0571FEC82
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008922 Genomic DNA. Translation: AAM39997.1.
RefSeqiNP_636073.1. NC_003902.1.
WP_011035921.1. NC_003902.1.

Genome annotation databases

EnsemblBacteriaiAAM39997; AAM39997; XCC0681.
GeneIDi1001338.
KEGGixcc:XCC0681.
PATRICi24072024. VBIXanCam115730_0747.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008922 Genomic DNA. Translation: AAM39997.1 .
RefSeqi NP_636073.1. NC_003902.1.
WP_011035921.1. NC_003902.1.

3D structure databases

ProteinModelPortali Q8PCP3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 190485.XCC0681.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM39997 ; AAM39997 ; XCC0681 .
GeneIDi 1001338.
KEGGi xcc:XCC0681.
PATRICi 24072024. VBIXanCam115730_0747.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284928.
KOi K00763.
OMAi QAVFHRY.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci XCAM190485:GIXZ-680-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Entry informationi

Entry nameiPNCB_XANCP
AccessioniPrimary (citable) accession number: Q8PCP3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: October 10, 2002
Last modified: September 3, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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