Q8P8U7 (GLK_XANCP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glucokinase
EC=2.7.1.2

Alternative name(s):
Glucose kinase

Gene names

Name:	glk
Ordered Locus Names:	XCC2137

Organism

Xanthomonas campestris pv. campestris

Taxonomic identifier

340 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas

Protein attributes

Sequence length	335 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP MF_00524
Subcellular location	Cytoplasm By similarity HAMAP MF_00524.
Sequence similarities	Belongs to the bacterial glucokinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glucokinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 335	335	Glucokinase HAMAP MF_00524		PRO_0000215142
Regions
	Nucleotide binding	11 – 16	6	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8P8U7 [UniParc]. Last modified October 10, 2002. Version 1. Checksum: BB4B02D88920A1B0	FASTA	335	35,520
	10 20 30 40 50 60 MTAPSKPVLV ADIGGTNARF ALADIDASVP LLDDTCREFA VVEFGSLGEA ARYYLDQIGV 70 80 90 100 110 120 QATKGVFAVA GRVDGDEARI TNHPWVISRS RTATMLGFST LHLINDFAAQ AMAISLLRPQ 130 140 150 160 170 180 DVVQVGGASW RPAPIELPRN YGVIGPGTGL GVGGLIIRNG RCFPLETEGG HVSFPPGTPE 190 200 210 220 230 240 EIRVLEILSE QFGRVSNERL ICGPGLVNIH RALSEIAGID PGPLEPKDIT ARAAAGDPRA 250 260 270 280 290 300 SRTIDLFCAI FGAIAGDMVL MQGAWDGVFL TGGLVPKVLD SLQHSGFRQR FEHKGRFSAI 310 320 330 MSRVPSLAVM HPHAGLLGAA AYAVDAERAL PGEQR

References

[1]

"Comparison of the genomes of two Xanthomonas pathogens with differing host specificities." da Silva A.C.R., Ferro J.A., Reinach F.C., Farah C.S., Furlan L.R., Quaggio R.B., Monteiro-Vitorello C.B., Van Sluys M.A., Almeida N.F. Jr., Alves L.M.C., do Amaral A.M., Bertolini M.C., Camargo L.E.A., Camarotte G., Cannavan F., Cardozo J., Chambergo F., Ciapina L.P. , Cicarelli R.M.B., Coutinho L.L., Cursino-Santos J.R., El-Dorry H., Faria J.B., Ferreira A.J.S., Ferreira R.C.C., Ferro M.I.T., Formighieri E.F., Franco M.C., Greggio C.C., Gruber A., Katsuyama A.M., Kishi L.T., Leite R.P., Lemos E.G.M., Lemos M.V.F., Locali E.C., Machado M.A., Madeira A.M.B.N., Martinez-Rossi N.M., Martins E.C., Meidanis J., Menck C.F.M., Miyaki C.Y., Moon D.H., Moreira L.M., Novo M.T.M., Okura V.K., Oliveira M.C., Oliveira V.R., Pereira H.A., Rossi A., Sena J.A.D., Silva C., de Souza R.F., Spinola L.A.F., Takita M.A., Tamura R.E., Teixeira E.C., Tezza R.I.D., Trindade dos Santos M., Truffi D., Tsai S.M., White F.F., Setubal J.C., Kitajima J.P. Nature 417:459-463(2002) [PubMed: 12024217] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33913 / NCPPB 528 / LMG 568.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008922 Genomic DNA. Translation: AAM41422.1.
RefSeq	NP_637498.1. NC_003902.1.
3D structure databases
ProteinModelPortal	Q8P8U7.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	998740.
GenomeReviews	Gene locus XCC2137 in contig AE008922_GR.
KEGG	xcc:XCC2137.
PATRIC	24075169. VBIXanCam115730_2288.
Phylogenomic databases
HOGENOM	HBG644410.
OMA	FADKGCM.
ProtClustDB	PRK00292.
Enzyme and pathway databases
BioCyc	XCAM190485:XCC2137-MONOMER.
Family and domain databases
HAMAP	MF_00524. Glucokinase. [Tree]
InterPro	IPR003836. Glucokinase. [Graphical view]
KO	K00845.
Pfam	PF02685. Glucokinase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00749. Glk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLK_XANCP

Accession

Primary (citable) accession number: Q8P8U7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 10, 2002
Last sequence update:	October 10, 2002
Last modified:	January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program