Reviewed, UniProtKB/Swiss-Prot Q8P4V7 (GLNE_XANCP)

Names and origin

Protein names

Recommended name:
    Glutamate-ammonia-ligase adenylyltransferase
    EC=2.7.7.42
Alternative name(s):
    [Glutamate--ammonia-ligase] adenylyltransferase
    Glutamine-synthetase adenylyltransferase
      Short name=ATase

Gene names

Name:	glnE
Ordered Locus Names:	XCC3599

Organism

Xanthomonas campestris pv. campestris [Complete proteome] [HAMAP]

Taxonomic identifier

340 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas

Protein attributes

Sequence length	937 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Adenylation and deadenylation of glutamine synthetase By similarity.
Catalytic activity	ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]. HAMAP MF_00802
Sequence similarities	Belongs to the glnE family.

Ontologies

Keywords
Domain	Repeat
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW [glutamate-ammonia-ligase] adenylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 937	937	Glutamate-ammonia-ligase adenylyltransferase HAMAP MF_00802		PRO_0000209286
Regions
	Region	91 – 300	210	GlnE 1 HAMAP MF_00802
	Region	598 – 814	217	GlnE 2 HAMAP MF_00802

Sequences

	Sequence		Length	Mass (Da)
	Q8P4V7-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 3A026930D62F380E	FASTA	937	102,203
	10 20 30 40 50 60 MSQPIPSASP ALAALIERAV ARVRHALPAD APWPEGVEHP LARVALASDF VVDTLARQPA 70 80 90 100 110 120 LLAHLAQPDP PPLPVPRLDP AQPQEWAAQL RRYRAAASAR LVWRDVLGLD DVDATLAGAT 130 140 150 160 170 180 TLAETCLQCA LQALEQQFST RHGQVIAEDG SVQRLVVFGL GKLGGGELNF SSDVDLVYAY 190 200 210 220 230 240 PQAGQSDGAR PLAAEEYFAR LGQQLARLLD ETTADGFSHR VDLRLRPFGS AGRVALSFNG 250 260 270 280 290 300 MDQYFQREGR DWERYAWLKA RAVAGDIAAG EAWLETLRPF VYRRYLDFTA LDGLRDMKAA 310 320 330 340 350 360 ITAEVAHHAR LDDIKRGPGG IREIEFLAQS LQLIRGGREA SLRERRLLPA LQALVDLGQI 370 380 390 400 410 420 DPPTGQALAD AYRFLRRVEN RLQMLRDAQT HALPQGEPER ERIALGLGYA HWQALLEALA 430 440 450 460 470 480 PHRTRVAAEF AELLAPRVHA TAPDTLADYW RALPEGDAAP LLGIGLHDPN NAHHMLADFA 490 500 510 520 530 540 QSSGVRALSD GARTRLDRVM PALLHAAIRA TQPDAALRRV LGLLQATLRR TSYLALLDEQ 550 560 570 580 590 600 PSALARLVDV LSRSALLAER LAAYPLLLDE LLDTRISGPL PDRAALHTAC VDTLQIDDTE 610 620 630 640 650 660 AALRELNERR LALSFRIALA TLDGRQQPVD STQQLAWLAE AVVQTVLQLA RRELVAAHGQ 670 680 690 700 710 720 VPGGAFAIIG YGSLGGLELG FGSDLDLVFL YDHPREVEAS DGKRPLEAGR WFARLAQKVM 730 740 750 760 770 780 TLLGAETGAG RLYDIDVRLR PDGGKGALVS SLASYRDYQR DRAWTWEHQA LVRARAVAGD 790 800 810 820 830 840 AALCEAFVQV RRETLTRVRD PALLHEDVRK MRARMRSELD RSDAGRLDLK QGAGGLVDLE 850 860 870 880 890 900 FLLQAGVLGQ AAQHPALLLA CATPALIDAL VQVQWLPAES AAPLHHAHAT LVEAGLSCTL 910 920 930 DRRPRLVVST PPIRDACQIV AAIADAQQLR FQPGKGA

References

[1]

"Comparison of the genomes of two Xanthomonas pathogens with differing host specificities." da Silva A.C.R., Ferro J.A., Reinach F.C., Farah C.S., Furlan L.R., Quaggio R.B., Monteiro-Vitorello C.B., Van Sluys M.A., Almeida N.F. Jr., Alves L.M.C., do Amaral A.M., Bertolini M.C., Camargo L.E.A., Camarotte G., Cannavan F., Cardozo J., Chambergo F., Ciapina L.P. , Cicarelli R.M.B., Coutinho L.L., Cursino-Santos J.R., El-Dorry H., Faria J.B., Ferreira A.J.S., Ferreira R.C.C., Ferro M.I.T., Formighieri E.F., Franco M.C., Greggio C.C., Gruber A., Katsuyama A.M., Kishi L.T., Leite R.P., Lemos E.G.M., Lemos M.V.F., Locali E.C., Machado M.A., Madeira A.M.B.N., Martinez-Rossi N.M., Martins E.C., Meidanis J., Menck C.F.M., Miyaki C.Y., Moon D.H., Moreira L.M., Novo M.T.M., Okura V.K., Oliveira M.C., Oliveira V.R., Pereira H.A., Rossi A., Sena J.A.D., Silva C., de Souza R.F., Spinola L.A.F., Takita M.A., Tamura R.E., Teixeira E.C., Tezza R.I.D., Trindade dos Santos M., Truffi D., Tsai S.M., White F.F., Setubal J.C., Kitajima J.P. Nature 417:459-463(2002) [PubMed: 12024217] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33913 / NCPPB 528 / LMG 568.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE012481 Genomic DNA. Translation: AAM42869.1.
RefSeq	NP_638945.1.
3D structure databases
HSSP	HSSP built from PDB template 1MUL based on UniProtKB P02342.
ModBase	Search...
Genome annotation databases
GeneID	1000163.
GenomeReviews	Gene locus XCC3599 in contig AE008922_GR.
KEGG	xcc:XCC3599.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8P4V7.
OMA	Q8P4V7. WERYAMI.
Enzyme and pathway databases
BioCyc	XCAM190485:XCC3599-MON.
BRENDA	2.7.7.42. 281360.
Family and domain databases
HAMAP	MF_00802. [Tree]
InterPro	IPR005190. GlnE. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
Pfam	PF08335. GlnD_UR_UTase. 1 hit. PF03710. GlnE. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLNE_XANCP

Accession

Primary (citable) accession number: Q8P4V7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 4, 2005
Last sequence update:	October 1, 2002
Last modified:	June 16, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)