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Q8P448 (SPEA_XANCP) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Biosynthetic arginine decarboxylase

Short name=ADC
EC=4.1.1.19
Gene names
Name:speA
Ordered Locus Names:XCC3868
OrganismXanthomonas campestris pv. campestris (strain ATCC 33913 / NCPPB 528 / LMG 568) [Reference proteome] [HAMAP]
Taxonomic identifier190485 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

Protein attributes

Sequence length628 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the biosynthesis of agmatine from arginine By similarity. HAMAP-Rule MF_01417

Catalytic activity

L-arginine = agmatine + CO2. HAMAP-Rule MF_01417

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01417

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01417

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Sequence caution

The sequence AAM43099.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 628628Biosynthetic arginine decarboxylase HAMAP-Rule MF_01417
PRO_0000149988

Regions

Region279 – 28911Substrate-binding Potential

Amino acid modifications

Modified residue991N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8P448 [UniParc].

Last modified March 29, 2004. Version 2.
Checksum: 4500A6D75CDC12F2

FASTA62869,036
        10         20         30         40         50         60 
MSDWSLDQAR KTYSIPHWAD GYFDVNDAGH VVVRPTADGP AVSLPEVVDA ARAAGAKLPL 

        70         80         90        100        110        120 
LVRFPDILGQ RLGKLQAAFA QAQADWDYAG GYTAVYPIKV NQHRGVAGTL ASHHGEGFGL 

       130        140        150        160        170        180 
EAGSKPELMA VLALSRPGGL IVCNGYKDRE YIRLALIGRK LGLQTFIVIE KPSELNLVLE 

       190        200        210        220        230        240 
EARALDVKPG LGVRMRLASL GAGKWQNSGG DKAKFGLSPR QVLDLWKSLR DTEYADSLNL 

       250        260        270        280        290        300 
LHFHMGSQIS NVRDIANGMR EATRYFVELS RLGAKISHVD VGGGLGIDYE GTRSRSYCSI 

       310        320        330        340        350        360 
NYGLHSYASN IVQPLASACE EHGLPPPRIV TECGRAMTAH HAVLIANVSE VEQAPEGRVP 

       370        380        390        400        410        420 
DAHDDEPAAI RHLREIHDEL DVRPAVELFQ EAQHFHAEGL SAYALGQIDL THRARIDDLF 

       430        440        450        460        470        480 
YAIAHGVRAR LSFDEKSHRP VLDELNERLV DKYFVNFSVF ESIPDVWAID QVFPIVPIER 

       490        500        510        520        530        540 
LNEAPQRRGI IADMTCDSDG MVKTYVENES LDSSLPLHGL NPGESYRIGF FLVGAYQEIL 

       550        560        570        580        590        600 
GDIHNLFGDT DAVEVAVDGT GYRIAQQRRG DTTDVMLDYV GYQLDTLRAT YAERIAAAQL 

       610        620 
PPERAQELHD ALEAGLTGYT YLSDEPLG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008922 Genomic DNA. Translation: AAM43099.1. Different initiation.
RefSeqNP_639208.2. NC_003902.1.

3D structure databases

ProteinModelPortalQ8P448.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING190485.XCC3868.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM43099; AAM43099; XCC3868.
GeneID1000446.
KEGGxcc:XCC3868.
PATRIC24078919. VBIXanCam115730_4139.

Phylogenomic databases

eggNOGCOG1166.
HOGENOMHOG000029191.
KOK01585.
OMAMIHFHIG.
OrthoDBEOG676Z0R.
ProtClustDBPRK05354.

Enzyme and pathway databases

BioCycXCAM190485:GIXZ-3866-MONOMER.

Family and domain databases

Gene3D2.40.37.10. 2 hits.
HAMAPMF_01417. SpeA.
InterProIPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022657. De-COase2_CS.
IPR022644. De-COase2_N.
IPR000183. Orn/DAP/Arg_de-COase.
[Graphical view]
PfamPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR01273. speA. 1 hit.
PROSITEPS00879. ODR_DC_2_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPEA_XANCP
AccessionPrimary (citable) accession number: Q8P448
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: March 29, 2004
Last modified: February 19, 2014
This is version 67 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families