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Q8P3Z4

- SYW_XANCP

UniProt

Q8P3Z4 - SYW_XANCP

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Protein

Tryptophan--tRNA ligase

Gene

trpS

Organism
Xanthomonas campestris pv. campestris (strain ATCC 33913 / NCPPB 528 / LMG 568)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl-tRNA(Trp).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei207 – 2071ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. tryptophan-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. tryptophanyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciXCAM190485:GIXZ-3921-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Tryptophan--tRNA ligaseUniRule annotation (EC:6.1.1.2UniRule annotation)
Alternative name(s):
Tryptophanyl-tRNA synthetaseUniRule annotation
Short name:
TrpRSUniRule annotation
Gene namesi
Name:trpSUniRule annotation
Ordered Locus Names:XCC3923
OrganismiXanthomonas campestris pv. campestris (strain ATCC 33913 / NCPPB 528 / LMG 568)
Taxonomic identifieri190485 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
ProteomesiUP000001010: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 431431Tryptophan--tRNA ligasePRO_0000136713Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi190485.XCC3923.

Structurei

3D structure databases

ProteinModelPortaliQ8P3Z4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi13 – 219"HIGH" region
Motifi204 – 2085"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0180.
HOGENOMiHOG000059939.
KOiK01867.
OMAiHIEMARA.
OrthoDBiEOG686NJQ.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
HAMAPiMF_00140_B. Trp_tRNA_synth_B.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
IPR024109. Trp-tRNA-ligase_bac-type.
[Graphical view]
PANTHERiPTHR10055. PTHR10055. 1 hit.
PfamiPF00579. tRNA-synt_1b. 1 hit.
[Graphical view]
PRINTSiPR01039. TRNASYNTHTRP.
TIGRFAMsiTIGR00233. trpS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8P3Z4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQMTTRVLTG ITPSGTPHLG NYVGAIRPAI QASTATDAES FYFLADLHSL
60 70 80 90 100
IKAQDPARTQ RSTLEIAASW LACGLDPDKV WFYRQSDVPE TTELMWLLTC
110 120 130 140 150
VAGKGILNRA HAYKAAMDKN RAEGEDEDAG VTAGLFMYPV LMAADILIFN
160 170 180 190 200
AHKVPVGRDQ IQHIEMARDF AQRFNHVYGQ DYFTLPDAVI DEQVATLPGL
210 220 230 240 250
DGRKMSKSYN NTIPLFAPRE ELRKLVFSIL TDSRAPGEAK DTQGSALFQL
260 270 280 290 300
YQAFATPQET AAFAQAFADG ISWADAKQQL FERIDLEIAP LRARYEALMA
310 320 330 340 350
EPAKIEATLR AGGARLRARY ATPLLAQLRD AVGLRDLSSQ ASAVGPATAV
360 370 380 390 400
KAALPVFKQY RESDGQFYFK LHDAAGTLLL QSDGFASPRE AGQLIARLKQ
410 420 430
AEDTTQLQLP GVQLPADAAP VLAALRALRE A
Length:431
Mass (Da):47,101
Last modified:October 1, 2002 - v1
Checksum:i1043117CB2239037
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008922 Genomic DNA. Translation: AAM43145.1.
RefSeqiNP_639263.1. NC_003902.1.

Genome annotation databases

EnsemblBacteriaiAAM43145; AAM43145; XCC3923.
GeneIDi1000585.
KEGGixcc:XCC3923.
PATRICi24079041. VBIXanCam115730_4198.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008922 Genomic DNA. Translation: AAM43145.1 .
RefSeqi NP_639263.1. NC_003902.1.

3D structure databases

ProteinModelPortali Q8P3Z4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 190485.XCC3923.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM43145 ; AAM43145 ; XCC3923 .
GeneIDi 1000585.
KEGGi xcc:XCC3923.
PATRICi 24079041. VBIXanCam115730_4198.

Phylogenomic databases

eggNOGi COG0180.
HOGENOMi HOG000059939.
KOi K01867.
OMAi HIEMARA.
OrthoDBi EOG686NJQ.

Enzyme and pathway databases

BioCyci XCAM190485:GIXZ-3921-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
HAMAPi MF_00140_B. Trp_tRNA_synth_B.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
IPR024109. Trp-tRNA-ligase_bac-type.
[Graphical view ]
PANTHERi PTHR10055. PTHR10055. 1 hit.
Pfami PF00579. tRNA-synt_1b. 1 hit.
[Graphical view ]
PRINTSi PR01039. TRNASYNTHTRP.
TIGRFAMsi TIGR00233. trpS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Entry informationi

Entry nameiSYW_XANCP
AccessioniPrimary (citable) accession number: Q8P3Z4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: October 29, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3