Q8P1D0 (Q8P1D0_STRP8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative dihydrofolate reductase EMBL AAL97586.1

Gene names

Name:	dfr EMBL AAL97586.1
Ordered Locus Names:	spyM18_0944

Organism

Streptococcus pyogenes serotype M18 [Complete proteome] [HAMAP]

Taxonomic identifier

301451 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	165 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8P1D0 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: BEF3C3FDA1851804	FASTA	165	19,376
	10 20 30 40 50 60 MTKEIIAIWA EDEAGLIGVA GKLPWYLPKE LEHFKKTTLH QAILMGRVTF EGMNCKRLSQ 70 80 90 100 110 120 RQTLVMTRNR DYQVDEVLTM TSIEKVLEWY HAQEKTLYII GGNKVLEAFN GYFDRIIKTV 130 140 150 160 IHHRFKGDTY RPNLDFSHFT QESQTFYARD AKNPYDFTVT ALKHK

References

[1]

"Genome sequence and comparative microarray analysis of serotype M18 group A Streptococcus strains associated with acute rheumatic fever outbreaks." Smoot J.C., Barbian K.D., Van Gompel J.J., Smoot L.M., Chaussee M.S., Sylva G.L., Sturdevant D.E., Ricklefs S.M., Porcella S.F., Parkins L.D., Beres S.B., Campbell D.S., Smith T.M., Zhang Q., Kapur V., Daly J.A., Veasy L.G., Musser J.M. Proc. Natl. Acad. Sci. U.S.A. 99:4668-4673(2002) [PubMed: 11917108] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MGAS8232 / Serotype M18.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE009949 Genomic DNA. Translation: AAL97586.1.
RefSeq	NP_607087.1. NC_003485.1.
3D structure databases
HSSP	HSSP built from PDB template 1DYR based on UniProtKB P16184.
ProteinModelPortal	Q8P1D0.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000030827; EBSTRP00000029749; EBSTRG00000030827.
GeneID	995212.
GenomeReviews	Gene locus spyM18_0944 in contig AE009949_GR.
KEGG	spm:spyM18_0944.
PATRIC	19748491. VBIStrPyo4396_0835.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000027355.
HOGENOM	HBG665708.
OMA	YITHILQ.
ProtClustDB	CLSK797453.
Enzyme and pathway databases
BioCyc	SPYO186103:SPYM18_0944-MONOMER.
Family and domain databases
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR017925. DHFR_CS. IPR001796. DHFR_dom. [Graphical view]
Gene3D	G3DSA:3.40.430.10. G3DSA:3.40.430.10. 1 hit.
KO	K00287.
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS00075. DHFR_1. 1 hit. PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8P1D0_STRP8

Accession

Primary (citable) accession number: Q8P1D0

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)