Q8P183 (Q8P183_STRP8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Extracellular hyaluronate lyase EMBL AAL97649.1

Gene names

Name:	hylA EMBL AAL97649.1
Ordered Locus Names:	spyM18_1014

Organism

Streptococcus pyogenes serotype M18 [Complete proteome] [HAMAP]

Taxonomic identifier

301451 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	805 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Lyase EMBL AAL97649.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	carbohydrate binding Inferred from electronic annotation. Source: InterPro carbon-oxygen lyase activity, acting on polysaccharides Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8P183 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 3B0AAD2A9A534DBB	FASTA	805	92,578
	10 20 30 40 50 60 MNTYFCTHHK QLLLYSNLFL SFAMMGQGTA IYADTLTSNS EPNNTYFQTQ TLTTTDSEKK 70 80 90 100 110 120 VVQPQQKDYY TELLDQWNSI IAGNDAYDKT NPDMVTFHNK AEKDAQNIIK SYQGPDHENR 130 140 150 160 170 180 TYLWEHAKDY SASTNITKTY RNIEKIAKQI TNPESCYYQD SKAIAIVKDG MAFMYEHAYN 190 200 210 220 230 240 LDRENHQTTG KENKENWWVY EIGTPRAINN TLSLMYPYFT QEEILKYTAP IEKFVPDPTR 250 260 270 280 290 300 FRVRAANFSP FEASSGNLID MGRVKLISGI LRKDDLEISD TIKAIEKVFT LVDEGNGFYQ 310 320 330 340 350 360 DGSLIDHVIT NAQSPLYKKG IAYTGAYGNV LIDGLSQLIP IIQKTKSPIE ADKMATIYHW 370 380 390 400 410 420 INHSFFPIIV RGEMMDMTQG RSISRFNAQS HVAGIEALRA ILRIADMSEE PHRLALKTRI 430 440 450 460 470 480 KTLVTQGNAF YNVYDNLKTY HDIKLMKELL SDTSVPVQKL DSYVASFNSM DKLALYNNKH 490 500 510 520 530 540 DFAFGLSMFS NRTQNYEAMN NENLHGWFTS DGMFYLYNND LGHYSENYWA TVNPYRLPGT 550 560 570 580 590 600 TETEQKPLEG TPENIKTNYQ QVGMTSLSDD AFVASKKLNN TSALAAMTFT NWNKSLTLNK 610 620 630 640 650 660 GWFILGNKII FVGSNIKNQS SHKAYTTIEQ RKENQKHPYH AYVNNQPVDL NNQLVDFTNT 670 680 690 700 710 720 KSIFLESDDS AQNIGYYFFK PTTLSISKAL QTGKWQNIKA DDKSPEAIKE VSNTFITIMQ 730 740 750 760 770 780 NHTQDDDRYA YMMLPNMTRQ EFENYISKLD IDLLENNDKL AAVYDHDSQQ MHVIHYEKKA 790 800 TMFSNHNLSH QGFYSFPHPV KQNQQ

References

[1]

"Genome sequence and comparative microarray analysis of serotype M18 group A Streptococcus strains associated with acute rheumatic fever outbreaks." Smoot J.C., Barbian K.D., Van Gompel J.J., Smoot L.M., Chaussee M.S., Sylva G.L., Sturdevant D.E., Ricklefs S.M., Porcella S.F., Parkins L.D., Beres S.B., Campbell D.S., Smith T.M., Zhang Q., Kapur V., Daly J.A., Veasy L.G., Musser J.M. Proc. Natl. Acad. Sci. U.S.A. 99:4668-4673(2002) [PubMed: 11917108] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MGAS8232 / Serotype M18.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE009949 Genomic DNA. Translation: AAL97649.1.
RefSeq	NP_607150.1. NC_003485.1.
3D structure databases
HSSP	HSSP built from PDB template 1LXM based on UniProtKB Q53591.
ProteinModelPortal	Q8P183.
SMR	Q8P183. Positions 67-780.
ModBase	Search...
Protein family/group databases
CAZy	PL8. Polysaccharide Lyase Family 8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000030130; EBSTRP00000029052; EBSTRG00000030130.
GeneID	995259.
GenomeReviews	Gene locus spyM18_1014 in contig AE009949_GR.
KEGG	spm:spyM18_1014.
PATRIC	19748631. VBIStrPyo4396_0902.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000027679.
HOGENOM	HBG698564.
OMA	TKTYRNI.
ProtClustDB	CLSK442844.
Enzyme and pathway databases
BioCyc	SPYO186103:SPYM18_1014-MONOMER.
Family and domain databases
InterPro	IPR008929. Chondroitin_lyas. IPR011013. Glyco_hydro-type_carb-bd. IPR014718. Glyco_hydro-type_carb-bd_sub. IPR012970. Lyase_8_alpha_N. IPR004103. Lyase_8_C. IPR003159. Lyase_8_central_dom. IPR012329. Lyase_8_N. [Graphical view]
Gene3D	G3DSA:2.70.98.10. Glyco_hydro_42_D5. 1 hit. G3DSA:2.60.220.10. Lyase_8_C. 1 hit. G3DSA:1.50.10.100. Lyase_8_N. 1 hit.
Pfam	PF02278. Lyase_8. 1 hit. PF08124. Lyase_8_N. 1 hit. [Graphical view]
SUPFAM	SSF48230. Chondroitin_lyas. 1 hit. SSF74650. Gal_mut_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8P183_STRP8

Accession

Primary (citable) accession number: Q8P183

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)