ID   CITX_STRP8              Reviewed;         192 AA.
AC   Q8P0Z2;
DT   25-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   16-JUN-2009, entry version 34.
DE   RecName: Full=Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase;
DE            EC=2.7.7.61;
DE   AltName: Full=Holo-ACP synthase;
DE   AltName: Full=Holo-citrate lyase synthase;
DE   AltName: Full=Apo-ACP nucleodityltransferase;
GN   Name=citX; OrderedLocusNames=spyM18_1141;
OS   Streptococcus pyogenes serotype M18.
OC   Bacteria; Firmicutes; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=301451;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGAS8232 / Serotype M18;
RX   MEDLINE=21927593; PubMed=11917108; DOI=10.1073/pnas.062526099;
RA   Smoot J.C., Barbian K.D., Van Gompel J.J., Smoot L.M., Chaussee M.S.,
RA   Sylva G.L., Sturdevant D.E., Ricklefs S.M., Porcella S.F.,
RA   Parkins L.D., Beres S.B., Campbell D.S., Smith T.M., Zhang Q.,
RA   Kapur V., Daly J.A., Veasy L.G., Musser J.M.;
RT   "Genome sequence and comparative microarray analysis of serotype M18
RT   group A Streptococcus strains associated with acute rheumatic fever
RT   outbreaks.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4668-4673(2002).
CC   -!- FUNCTION: Transfers 2-(5''-triphosphoribosyl)-3'-
CC       dephosphocoenzyme-A on a serine residue to the apo-acyl carrier
CC       protein (gamma chain) of the citrate lyase to yield holo-acyl
CC       carrier protein (By similarity).
CC   -!- CATALYTIC ACTIVITY: 2'-(5-triphosphoribosyl)-3'-dephospho-CoA +
CC       citrate lyase apo-[acyl-carrier-protein] = citrate lyase holo-
CC       [acyl-carrier-protein] + diphosphate.
CC   -!- SIMILARITY: Belongs to the citX family.
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DR   EMBL; AE009949; AAL97761.1; -; Genomic_DNA.
DR   RefSeq; NP_607262.1; -.
DR   GeneID; 993940; -.
DR   GenomeReviews; AE009949_GR; spyM18_1141.
DR   KEGG; spm:spyM18_1141; -.
DR   HOGENOM; Q8P0Z2; -.
DR   OMA; Q8P0Z2; TGYEYYL.
DR   BioCyc; SPYO186103:SPYM18_1141-MON; -.
DR   GO; GO:0050519; F:holo-citrate lyase synthase activity; IEA:HAMAP.
DR   HAMAP; MF_00398; -; 1.
DR   InterPro; IPR005551; CitX.
DR   Pfam; PF03802; CitX; 1.
DR   TIGRFAMs; TIGR03124; ctirate_citX; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Nucleotidyltransferase; Transferase.
FT   CHAIN         1    192       Probable apo-citrate lyase
FT                                phosphoribosyl-dephospho-CoA transferase.
FT                                /FTId=PRO_0000214691.
SQ   SEQUENCE   192 AA;  21506 MW;  97AB5835CC1C3B7C CRC64;
     MCKDTYFSGE AIQLSDMLRA REERALRQLH LLKEYPEGSL LSVTMNIPGP IKTSPKLLEA
     FDIVIKAIQT ALADDKICYQ LRLLPTTGYE YYLITSLPSQ DLKLKMIALE TDLPIGRLMD
     LDVLVLSNGR PSPISRTTLG APPRQCFICS KEAKVCGRLR KHSVEEMQTA ISKLLHSFFN
     KDNQSSSSDK TG
//