ID   DEOC1_STAAW             Reviewed;         220 AA.
AC   Q8NYR1;
DT   01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   16-JUN-2009, entry version 45.
DE   RecName: Full=Deoxyribose-phosphate aldolase 1;
DE            EC=4.1.2.4;
DE   AltName: Full=Phosphodeoxyriboaldolase 1;
DE            Short=Deoxyriboaldolase 1;
DE            Short=DERA 1;
GN   Name=deoC1; Synonyms=dra; OrderedLocusNames=MW0112;
OS   Staphylococcus aureus (strain MW2).
OC   Bacteria; Firmicutes; Bacillales; Staphylococcus.
OX   NCBI_TaxID=196620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   MEDLINE=22040717; PubMed=12044378; DOI=10.1016/S0140-6736(02)08713-5;
RA   Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A.,
RA   Nagai Y., Iwama N., Asano K., Naimi T., Kuroda H., Cui L.,
RA   Yamamoto K., Hiramatsu K.;
RT   "Genome and virulence determinants of high virulence community-
RT   acquired MRSA.";
RL   Lancet 359:1819-1827(2002).
CC   -!- CATALYTIC ACTIVITY: 2-deoxy-D-ribose 5-phosphate = D-
CC       glyceraldehyde 3-phosphate + acetaldehyde.
CC   -!- PATHWAY: Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate
CC       degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-
CC       deoxy-D-ribose 1-phosphate: step 2/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the deoC/fbaB aldolase family. DeoC type 1
CC       subfamily.
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DR   EMBL; BA000033; BAB93977.1; -; Genomic_DNA.
DR   RefSeq; NP_644927.1; -.
DR   HSSP; Q9X1P5; 1O0Y.
DR   GeneID; 1004862; -.
DR   GenomeReviews; BA000033_GR; MW0112.
DR   KEGG; sam:MW0112; -.
DR   HOGENOM; Q8NYR1; -.
DR   OMA; Q8NYR1; FPSGKHH.
DR   BioCyc; SAUR196620:MW0112-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004139; F:deoxyribose-phosphate aldolase activity; IEA:HAMAP.
DR   GO; GO:0016052; P:carbohydrate catabolic process; IEA:HAMAP.
DR   GO; GO:0009264; P:deoxyribonucleotide catabolic process; IEA:InterPro.
DR   HAMAP; MF_00114; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR011343; DeoC.
DR   InterPro; IPR002915; DeoC/AroFGH_arch.
DR   Gene3D; G3DSA:3.20.20.70; Aldolase_TIM; 1.
DR   PANTHER; PTHR10889; DeoC; 1.
DR   Pfam; PF01791; DeoC; 1.
DR   PIRSF; PIRSF001357; DeoC; 1.
DR   TIGRFAMs; TIGR00126; deoC; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Lyase; Schiff base.
FT   CHAIN         1    220       Deoxyribose-phosphate aldolase 1.
FT                                /FTId=PRO_0000057265.
FT   ACT_SITE    151    151       Schiff-base intermediate with
FT                                acetaldehyde (By similarity).
FT   ACT_SITE    180    180       By similarity.
SQ   SEQUENCE   220 AA;  23501 MW;  853E1D7EBEE15812 CRC64;
     MKFEKYIDHT LLKPESTRTQ IDQIIDEAKA YNFKSVCVNP THVKYAAERL ADSEVLVCTV
     IGFPLGASTT ATKAFETEDA IQNGADEIDM VINIGALKDG RFDDVQQDIE AVVKVAKGHT
     VKVIIETVLL DHDEIVKASE LTKAAGADFV KTSTGFAGGG ATAEDVKLMK DTVGADVEVK
     ASGGVRNLED FNKMVEAGAT RIGASAGVQI MQGLEADSDY
//