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Protein

Uncharacterized response regulatory protein MW0198

Gene

MW0198

Organism
Staphylococcus aureus (strain MW2)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Probable member of the two-component regulatory system MW0199/MW0198.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi170 – 191H-T-H motifPROSITE-ProRule annotationAdd BLAST22
DNA bindingi217 – 240H-T-H motifPROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation, Two-component regulatory system

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciSAUR196620:GJ9Z-200-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized response regulatory protein MW0198
Gene namesi
Ordered Locus Names:MW0198
OrganismiStaphylococcus aureus (strain MW2)
Taxonomic identifieri196620 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000418 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002991131 – 252Uncharacterized response regulatory protein MW0198Add BLAST252

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei554-aspartylphosphatePROSITE-ProRule annotation1

Post-translational modificationi

Phosphorylated by MW0199.Curated

Keywords - PTMi

Phosphoprotein

Structurei

3D structure databases

ProteinModelPortaliQ8NYJ9.
SMRiQ8NYJ9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 118Response regulatoryPROSITE-ProRule annotationAdd BLAST116
Domaini153 – 250HTH araC/xylS-typePROSITE-ProRule annotationAdd BLAST98

Sequence similaritiesi

Contains 1 HTH araC/xylS-type DNA-binding domain.PROSITE-ProRule annotation
Contains 1 response regulatory domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000059795.
KOiK07720.
OMAiDHITHIR.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
InterProiIPR011006. CheY-like_superfamily.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
SMARTiSM00342. HTH_ARAC. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
SSF52172. SSF52172. 1 hit.
PROSITEiPS01124. HTH_ARAC_FAMILY_2. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8NYJ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFKVVICDDE RIIREGLKQI IPWGDYHFNT IYTAKDGVEA LSLIQQHQPE
60 70 80 90 100
LVITDIRMPR KNGVDLLNDI AHLDCNVIIL SSYDDFEYMK AGIQHHVLDY
110 120 130 140 150
LLKPVDHAQL EVILGRLVRT LLEQQSQNGR SLASCHDAFQ PLLKVEYDDY
160 170 180 190 200
YVNQIVDQIK QSYQTKVTVS DLIQHIDVSE SYAMRTFKDH VGITIVDYLN
210 220 230 240 250
RYRILQSLQL LDRHYKHYEI ADKVGFSEYK MFSYHFKKYL QMSPSDYCKQ

AK
Length:252
Mass (Da):29,599
Last modified:October 1, 2002 - v1
Checksum:iF42C8E41A0CE4082
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000033 Genomic DNA. Translation: BAB94063.1.
RefSeqiWP_000477521.1. NC_003923.1.

Genome annotation databases

EnsemblBacteriaiBAB94063; BAB94063; BAB94063.
GeneIDi28379466.
KEGGisam:MW0198.
PATRICi19566864. VBIStaAur44266_0214.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000033 Genomic DNA. Translation: BAB94063.1.
RefSeqiWP_000477521.1. NC_003923.1.

3D structure databases

ProteinModelPortaliQ8NYJ9.
SMRiQ8NYJ9.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB94063; BAB94063; BAB94063.
GeneIDi28379466.
KEGGisam:MW0198.
PATRICi19566864. VBIStaAur44266_0214.

Phylogenomic databases

HOGENOMiHOG000059795.
KOiK07720.
OMAiDHITHIR.

Enzyme and pathway databases

BioCyciSAUR196620:GJ9Z-200-MONOMER.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
InterProiIPR011006. CheY-like_superfamily.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
SMARTiSM00342. HTH_ARAC. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
SSF52172. SSF52172. 1 hit.
PROSITEiPS01124. HTH_ARAC_FAMILY_2. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY198_STAAW
AccessioniPrimary (citable) accession number: Q8NYJ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: October 1, 2002
Last modified: November 2, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.