Reviewed, UniProtKB/Swiss-Prot Q8NXY1 (ARAB_STAAW)

Names and origin

Protein names

Recommended name:
    Ribulokinase
    EC=2.7.1.16

Gene names

Name:	araB
Ordered Locus Names:	MW0507

Organism

Staphylococcus aureus (strain MW2) [Complete proteome] [HAMAP]

Taxonomic identifier

196620 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	545 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate. HAMAP MF_00520
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 2/3. HAMAP MF_00520
Sequence similarities	Belongs to the ribulokinase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	L-arabinose catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ribulokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 545	545	Ribulokinase HAMAP MF_00520		PRO_0000198371

Sequences

	Sequence		Length	Mass (Da)
	Q8NXY1-1 [UniParc]. Last modified October 10, 2002. Version 1. Checksum: 9DFD11D67B668C74	FASTA	545	60,967
	10 20 30 40 50 60 MSYSIGIDYG TASGRVFLIN TTNGQVVSKF VKPYTHGVIE SELNGLKIPH TYALQNSNDY 70 80 90 100 110 120 LEIMEEGISY IVRESKIDPD NIVGIGIDFT SSTIIFTDEN LNPVHNLKQF KNNPHAYVKL 130 140 150 160 170 180 WKHHGAYKEA EKLYQTAIEN NNKWLGHYGY NVSSEWMIPK IMEVMNRAPE IMEKTAYIME 190 200 210 220 230 240 AGDWIVNKLT NKNIRSNCGL GFKAFWEEET GFHYDLFDKI DPKLSKVIQD KVSAPVVNIG 250 260 270 280 290 300 EAVGKLDDKM AQKLGLSKET MVSPFIIDAH ASLLGIGSEK DKEMTMVMGT STCHLMLNEK 310 320 330 340 350 360 QHQVPGISGS VKGAIIPELF AYEAGQSAVG DLFEYVAKQA PKSYVDEAAN RNMTVFELMN 370 380 390 400 410 420 EKIKHQMPGE SGLIALDWHN GNRSVLSDSN LTGCIFGLTL QTKHEDIYRA YLEATAFGTK 430 440 450 460 470 480 MIMQQYQDWH MEVEKVFACG GIPKKNAVMM DIYANVLNKK LIVMDSEYAP AIGAAILGAV 490 500 510 520 530 540 SGGAHNSIND AVDAMKEPIL YEINPEAEKV QRYETLFKAY KALHDIHGYK KANIMKDIQS LRVEG

References

[1]

"Genome and virulence determinants of high virulence community-acquired MRSA." Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y., Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K. Lancet 359:1819-1827(2002) [PubMed: 12044378] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000033 Genomic DNA. Translation: BAB94372.1.
RefSeq	NP_645324.1.
3D structure databases
SMR	Q8NXY1. Positions 2-521.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8NXY1.
Genome annotation databases
GeneID	1002618.
GenomeReviews	Gene locus MW0507 in contig BA000033_GR.
KEGG	sam:MW0507.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1069.
HOGENOM	HBG312681.
OMA	NGRRTPD.
Enzyme and pathway databases
BioCyc	SAUR196620:MW0507-MONOMER.
Family and domain databases
HAMAP	MF_00520. Ribulokinase. [Tree]
InterPro	IPR000577. Carb_kinase_FGGY. IPR018485. Carb_kinase_FGGY_C. IPR018484. Carb_kinase_FGGY_N. IPR005929. L_ribulokin. [Graphical view]
PANTHER	PTHR10196. FGGY_kin. 1 hit.
Pfam	PF02782. FGGY_C. 1 hit. PF00370. FGGY_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ARAB_STAAW

Accession

Primary (citable) accession number: Q8NXY1

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 10, 2002
Last sequence update:	October 10, 2002
Last modified:	January 19, 2010
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)