Q8NXW4 (PTAS_STAAW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphate acetyltransferase
EC=2.3.1.8

Alternative name(s):
Phosphotransacetylase

Gene names

Name:	pta
Ordered Locus Names:	MW0543

Organism

Staphylococcus aureus (strain MW2) [Complete proteome] [HAMAP]

Taxonomic identifier

196620 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	328 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + phosphate = CoA + acetyl phosphate.
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphate acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 328	328	Phosphate acetyltransferase		PRO_0000179145

Sequences

	Sequence		Length	Mass (Da)
	Q8NXW4 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: BD0C9BCCC0DCC76F	FASTA	328	34,922
	10 20 30 40 50 60 MADLLNVLKD KLSGKNVKIV LPEGEDERVL TAATQLQATD YVTPIVLGDE TKVQSLAQKL 70 80 90 100 110 120 DLDISNIELI NPATSELKAE LVQSFVERRK GKATEEQAQE LLNNVNYFGT MLVYAGKADG 130 140 150 160 170 180 LVSGAAHSTG DTVRPALQII KTKPGVSRTS GIFFMIKGDV QYIFGDCAIN PELDSQGLAE 190 200 210 220 230 240 IAVESAKSAL SFGMDPKVAM LSFSTKGSAK SDDVTKVQEA VKLAQQKAEE EKLEAIIDGE 250 260 270 280 290 300 FQFDAAIVPG VAEKKAPGAK LQGDANVFVF PSLEAGNIGY KIAQRLGGYD AVGPVLQGLN 310 320 SPVNDLSRGC SIEDVYNLSI ITAAQALQ

References

[1]

"Genome and virulence determinants of high virulence community-acquired MRSA." Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y., Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K. Lancet 359:1819-1827(2002) [PubMed: 12044378] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MW2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000033 Genomic DNA. Translation: BAB94408.1.
RefSeq	NP_645360.1. NC_003923.1.
3D structure databases
ProteinModelPortal	Q8NXW4.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8NXW4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000026761; EBSTAP00000025800; EBSTAG00000026760.
GeneID	1002654.
GenomeReviews	Gene locus MW0543 in contig BA000033_GR.
KEGG	sam:MW0543.
PATRIC	19567622. VBIStaAur44266_0573.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0280.
GeneTree	EBGT00050000025364.
HOGENOM	HBG576804.
OMA	GCSTEDV.
ProtClustDB	PRK09653.
Enzyme and pathway databases
BioCyc	SAUR196620:MW0543-MONOMER.
Family and domain databases
InterPro	IPR012147. P_Ac_Bu_trans. IPR004614. P_AcTrfase. IPR002505. PTA_PTB. [Graphical view]
KO	K00625.
Pfam	PF01515. PTA_PTB. 1 hit. [Graphical view]
PIRSF	PIRSF000428. P_Ac_trans. 1 hit.
TIGRFAMs	TIGR00651. Pta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PTAS_STAAW

Accession

Primary (citable) accession number: Q8NXW4

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2003
Last sequence update:	October 1, 2002
Last modified:	January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program