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Q8NXG7

- 2NPD_STAAW

UniProt

Q8NXG7 - 2NPD_STAAW

Protein

Probable nitronate monooxygenase

Gene

MW0803

Organism
Staphylococcus aureus (strain MW2)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    Catalyzes the oxidation of alkyl nitronates to produce the corresponding carbonyl compounds and nitrites.By similarity

    Catalytic activityi

    Ethylnitronate + O2 = acetaldehyde + nitrite + other products.

    Cofactori

    Binds 1 FMN per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei182 – 1821Proton acceptorSequence Analysis
    Binding sitei182 – 1821SubstrateBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi21 – 233FMNBy similarity
    Nucleotide bindingi216 – 2183FMNBy similarity
    Nucleotide bindingi239 – 2402FMNBy similarity

    GO - Molecular functioni

    1. nitronate monooxygenase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Monooxygenase, Oxidoreductase

    Keywords - Ligandi

    Flavoprotein, FMN

    Enzyme and pathway databases

    BioCyciSAUR196620:GJ9Z-825-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable nitronate monooxygenase (EC:1.13.12.16)
    Alternative name(s):
    Nitroalkane oxidase
    Gene namesi
    Ordered Locus Names:MW0803
    OrganismiStaphylococcus aureus (strain MW2)
    Taxonomic identifieri196620 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000000418: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 355355Probable nitronate monooxygenasePRO_0000360896Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi196620.MW0803.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8NXG7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the nitronate monooxygenase family.Curated

    Phylogenomic databases

    eggNOGiCOG2070.
    HOGENOMiHOG000123287.
    KOiK00459.
    OMAiCHIDTTI.
    OrthoDBiEOG6G7R1T.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    InterProiIPR004136. 2Npropane_dOase.
    IPR013785. Aldolase_TIM.
    [Graphical view]
    PfamiPF03060. NMO. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8NXG7-1 [UniParc]FASTAAdd to Basket

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    MWNKNRLTQM LSIEYPIIQA GMAGSTTPKL VASVSNSGGL GTIGAGYFNT    50
    QQLEDEIDYV RQLTSNSFGV NVFVPSQQSY TSSQIENMNA WLKPYRRALH 100
    LEEPVVKITE EQQFKCHIDT TIKKQVPVCC FTFGIPSESI IKRLKEANIK 150
    LIGTATSVDE AIANEKAGMD AIVAQGSEAG GHRGSFLKPK NQLPMVGTIS 200
    LVPQIVDVVS IPVIAAGGIM DGRGVLASIV LGAEGVQMGT AFLTSQDSNA 250
    SELLRDAIIN SKETDTVVTK AFSGKLARGI NNRFIEEMSQ YEGDIPDYPI 300
    QNELTSSIRK AAANIGDKEL THMWSGQSPR LATTHPANTI MSNIINQINQ 350
    IMQYK 355
    Length:355
    Mass (Da):38,582
    Last modified:October 1, 2002 - v1
    Checksum:iC3453C9EBBAEB37C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000033 Genomic DNA. Translation: BAB94668.1.
    RefSeqiNP_645620.1. NC_003923.1.

    Genome annotation databases

    EnsemblBacteriaiBAB94668; BAB94668; BAB94668.
    GeneIDi1002915.
    KEGGisam:MW0803.
    PATRICi19568171. VBIStaAur44266_0846.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000033 Genomic DNA. Translation: BAB94668.1 .
    RefSeqi NP_645620.1. NC_003923.1.

    3D structure databases

    ProteinModelPortali Q8NXG7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 196620.MW0803.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB94668 ; BAB94668 ; BAB94668 .
    GeneIDi 1002915.
    KEGGi sam:MW0803.
    PATRICi 19568171. VBIStaAur44266_0846.

    Phylogenomic databases

    eggNOGi COG2070.
    HOGENOMi HOG000123287.
    KOi K00459.
    OMAi CHIDTTI.
    OrthoDBi EOG6G7R1T.

    Enzyme and pathway databases

    BioCyci SAUR196620:GJ9Z-825-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    InterProi IPR004136. 2Npropane_dOase.
    IPR013785. Aldolase_TIM.
    [Graphical view ]
    Pfami PF03060. NMO. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MW2.

    Entry informationi

    Entry namei2NPD_STAAW
    AccessioniPrimary (citable) accession number: Q8NXG7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 20, 2009
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3