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Q8NXG7

- 2NPD_STAAW

UniProt

Q8NXG7 - 2NPD_STAAW

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Protein

Probable nitronate monooxygenase

Gene

MW0803

Organism
Staphylococcus aureus (strain MW2)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the oxidation of alkyl nitronates to produce the corresponding carbonyl compounds and nitrites.By similarity

Catalytic activityi

Ethylnitronate + O2 = acetaldehyde + nitrite + other products.

Cofactori

FMNBy similarityNote: Binds 1 FMN per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei182 – 1821Proton acceptorSequence Analysis
Binding sitei182 – 1821SubstrateBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi21 – 233FMNBy similarity
Nucleotide bindingi216 – 2183FMNBy similarity
Nucleotide bindingi239 – 2402FMNBy similarity

GO - Molecular functioni

  1. nitronate monooxygenase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Monooxygenase, Oxidoreductase

Keywords - Ligandi

Flavoprotein, FMN

Enzyme and pathway databases

BioCyciSAUR196620:GJ9Z-825-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable nitronate monooxygenase (EC:1.13.12.16)
Alternative name(s):
Nitroalkane oxidase
Gene namesi
Ordered Locus Names:MW0803
OrganismiStaphylococcus aureus (strain MW2)
Taxonomic identifieri196620 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000000418: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 355355Probable nitronate monooxygenasePRO_0000360896Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi196620.MW0803.

Structurei

3D structure databases

ProteinModelPortaliQ8NXG7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the nitronate monooxygenase family.Curated

Phylogenomic databases

eggNOGiCOG2070.
HOGENOMiHOG000123287.
KOiK00459.
OMAiCHIDTTI.
OrthoDBiEOG6G7R1T.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR004136. 2Npropane_dOase.
IPR013785. Aldolase_TIM.
[Graphical view]
PfamiPF03060. NMO. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8NXG7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MWNKNRLTQM LSIEYPIIQA GMAGSTTPKL VASVSNSGGL GTIGAGYFNT
60 70 80 90 100
QQLEDEIDYV RQLTSNSFGV NVFVPSQQSY TSSQIENMNA WLKPYRRALH
110 120 130 140 150
LEEPVVKITE EQQFKCHIDT TIKKQVPVCC FTFGIPSESI IKRLKEANIK
160 170 180 190 200
LIGTATSVDE AIANEKAGMD AIVAQGSEAG GHRGSFLKPK NQLPMVGTIS
210 220 230 240 250
LVPQIVDVVS IPVIAAGGIM DGRGVLASIV LGAEGVQMGT AFLTSQDSNA
260 270 280 290 300
SELLRDAIIN SKETDTVVTK AFSGKLARGI NNRFIEEMSQ YEGDIPDYPI
310 320 330 340 350
QNELTSSIRK AAANIGDKEL THMWSGQSPR LATTHPANTI MSNIINQINQ

IMQYK
Length:355
Mass (Da):38,582
Last modified:October 1, 2002 - v1
Checksum:iC3453C9EBBAEB37C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000033 Genomic DNA. Translation: BAB94668.1.
RefSeqiNP_645620.1. NC_003923.1.

Genome annotation databases

EnsemblBacteriaiBAB94668; BAB94668; BAB94668.
GeneIDi1002915.
KEGGisam:MW0803.
PATRICi19568171. VBIStaAur44266_0846.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000033 Genomic DNA. Translation: BAB94668.1 .
RefSeqi NP_645620.1. NC_003923.1.

3D structure databases

ProteinModelPortali Q8NXG7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 196620.MW0803.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB94668 ; BAB94668 ; BAB94668 .
GeneIDi 1002915.
KEGGi sam:MW0803.
PATRICi 19568171. VBIStaAur44266_0846.

Phylogenomic databases

eggNOGi COG2070.
HOGENOMi HOG000123287.
KOi K00459.
OMAi CHIDTTI.
OrthoDBi EOG6G7R1T.

Enzyme and pathway databases

BioCyci SAUR196620:GJ9Z-825-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
InterProi IPR004136. 2Npropane_dOase.
IPR013785. Aldolase_TIM.
[Graphical view ]
Pfami PF03060. NMO. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MW2.

Entry informationi

Entry namei2NPD_STAAW
AccessioniPrimary (citable) accession number: Q8NXG7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: October 1, 2002
Last modified: November 26, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3