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Q8NXF1

- G6PI_STAAW

UniProt

Q8NXF1 - G6PI_STAAW

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Staphylococcus aureus (strain MW2)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 69 (01 Oct 2014)
      Sequence version 1 (10 Oct 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei285 – 2851Proton donorUniRule annotation
    Active sitei306 – 3061UniRule annotation
    Active sitei420 – 4201UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciSAUR196620:GJ9Z-866-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:MW0844
    OrganismiStaphylococcus aureus (strain MW2)
    Taxonomic identifieri196620 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000000418: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 443443Glucose-6-phosphate isomerasePRO_0000180730Add
    BLAST

    Proteomic databases

    PRIDEiQ8NXF1.

    Interactioni

    Protein-protein interaction databases

    STRINGi196620.MW0844.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8NXF1.
    SMRiQ8NXF1. Positions 4-443.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000100403.
    KOiK01810.
    OMAiLANFNPK.
    OrthoDBiEOG64R61J.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8NXF1-1 [UniParc]FASTAAdd to Basket

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    MTHIQLDFSK TLEFFGEHEL KQQQEIVKSI HKTIHEGTGA GSDFLGWVDL    50
    PVDYDKEEFS RIVEASKRIK ENSDVLVVIG IGGSYLGARA AIEMLTSSFR 100
    NSNEYPEIVF VGNHLSSTYT KELVDYLADK DFSVNVISKS GTTTEPAVAF 150
    RLFKQLVEER YGKEEAQKRI FATTDKEKGA LKQLATNEGY ETFIVPDDVG 200
    GRYSVLTAVG LLPIATAGIN IEAMMIGAAK AREELSSDKL EENIAYQYAT 250
    IRNILYAKGY TTEMLINYEP SMQYFNEWWK QLFGESEGKD FKGIYPSSAN 300
    YTTDLHSLGQ YVQEGRRFLF ETVVKVNHPK YDITIEKDSD DLDGLNYLAG 350
    KTIDEVNTKA FEGTLLAHTD GGVPNMVVNI PQLDEETFGY VVYFFELACA 400
    MSGYQLGVNP FNQPGVEAYK QNMFALLGKP GFEDLKKELE ERL 443
    Length:443
    Mass (Da):49,808
    Last modified:October 10, 2002 - v1
    Checksum:iDF9A8E633F8BD099
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000033 Genomic DNA. Translation: BAB94709.1.
    RefSeqiNP_645661.1. NC_003923.1.

    Genome annotation databases

    EnsemblBacteriaiBAB94709; BAB94709; BAB94709.
    GeneIDi1002956.
    KEGGisam:MW0844.
    PATRICi19568255. VBIStaAur44266_0889.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000033 Genomic DNA. Translation: BAB94709.1 .
    RefSeqi NP_645661.1. NC_003923.1.

    3D structure databases

    ProteinModelPortali Q8NXF1.
    SMRi Q8NXF1. Positions 4-443.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 196620.MW0844.

    Proteomic databases

    PRIDEi Q8NXF1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB94709 ; BAB94709 ; BAB94709 .
    GeneIDi 1002956.
    KEGGi sam:MW0844.
    PATRICi 19568255. VBIStaAur44266_0889.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000100403.
    KOi K01810.
    OMAi LANFNPK.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci SAUR196620:GJ9Z-866-MONOMER.

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MW2.

    Entry informationi

    Entry nameiG6PI_STAAW
    AccessioniPrimary (citable) accession number: Q8NXF1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 10, 2002
    Last sequence update: October 10, 2002
    Last modified: October 1, 2014
    This is version 69 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3