Reviewed,
UniProtKB/Swiss-Prot Q8NWU6 (TYRA_STAAW)
Last modified
June 16, 2009.
Version 36.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Prephenate dehydrogenase Short name=PDH EC=1.3.1.12 | ||||
| Gene names |
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| Organism | Staphylococcus aureus (strain MW2) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 196620 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Staphylococcus |
Protein attributes
| Sequence length | 363 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Predicted. |
General annotation (Comments)
| Catalytic activity | Prephenate + NAD+ = 4-hydroxyphenylpyruvate + CO2 + NADH. |
| Pathway | Amino-acid biosynthesis; L-tyrosine biosynthesis; L-tyrosine from prephenate: step 1/2. |
| Sequence similarities | Contains 1 prephenate/arogenate dehydrogenase domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Aromatic amino acid biosynthesis Tyrosine biosynthesis |
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tyrosine biosynthetic processInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | amino acid binding Inferred from electronic annotation. Source: InterPro prephenate dehydrogenase (NADP+) activityInferred from electronic annotation. Source: InterPro prephenate dehydrogenase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Genome and virulence determinants of high virulence community-acquired MRSA." Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y., Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K. Lancet 359:1819-1827(2002) [PubMed: 12044378] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| BA000033 Genomic DNA. Translation: BAB95117.1. | |
| RefSeq | NP_646069.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1003364. |
| GenomeReviews | Gene locus MW1252 in contig BA000033_GR. |
| KEGG | sam:MW1252. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q8NWU6. |
| OMA | Q8NWU6. QRAIRWG. |
Enzyme and pathway databases | |
| BioCyc | SAUR196620:MW1252-MON. |
Family and domain databases | |
| InterPro | IPR002912. ACT_bd. IPR003099. Prephen_DH. [Graphical view] |
| PANTHER | PTHR21363. Prephen_DH. 1 hit. |
| Pfam | PF01842. ACT. 1 hit. PF02153. PDH. 1 hit. [Graphical view] |
| PROSITE | PS51176. PDH_ADH. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | TYRA_STAAW | ||||||||
| Accession | Primary (citable) accession number: Q8NWU6 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


