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Q8NUR9 (Q8NUR9_STAAW) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Hydroxymethylglutaryl-CoA reductase EMBL BAB96331.1
Gene names
Name:mvaA EMBL BAB96331.1
Ordered Locus Names:MW2466
OrganismStaphylococcus aureus (strain MW2) [Complete proteome] [HAMAP]
Taxonomic identifier196620 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length426 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the HMG-CoA reductase family. RuleBase RU004268

Ontologies

Keywords
   Molecular functionOxidoreductase RuleBase RU004269
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcoenzyme A metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncoenzyme binding

Inferred from electronic annotation. Source: InterPro

hydroxymethylglutaryl-CoA reductase (NADPH) activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q8NUR9 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 1CFFC2EFC22D9DD0

FASTA42646,329
        10         20         30         40         50         60 
MQNLDKNFRH LSRKEKLQQL VDKQWLSEEQ FDILLNHPLI DEEVANSLIE NVIAQGALPV 

        70         80         90        100        110        120 
GLLPNIIVDD KAYVVPMMVE EPSVVAAASY GAKLVNQTGG FKTVSSERIM IGQIVFDGVD 

       130        140        150        160        170        180 
DTEKLSADIK ALEKQIHKIA DEAYPSIKAR GGGYQRIAID TFPEQQLLSL KVFVDTKDAM 

       190        200        210        220        230        240 
GANMLNTILE AITAFLKNEF PQSDILMSIL SNHATASVVK VQGEIDVKDL ARGERTGEEV 

       250        260        270        280        290        300 
AKRMERASVL AQVDIHRAAT HNKGVMNGIH AVVLATGNDT RGAEASAHAY ASRDGQYRGI 

       310        320        330        340        350        360 
ATWRYDQDRQ RLIGTIEVPM TLAIVGGGTK VLPIAKASLE LLNVESAQEL GHVVAAVGLA 

       370        380        390        400        410        420 
QNFAACRALV SEGIQQGHMS LQYKSLAIVV GAKGDEIAKV AEALKKEPRA NTQAAERILQ 


DLRSQQ

« Hide

References

[1]"Genome and virulence determinants of high virulence community-acquired MRSA."
Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y., Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.
Lancet 359:1819-1827(2002) [PubMed: 12044378] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000033 Genomic DNA. Translation: BAB96331.1.
RefSeqNP_647283.1. NC_003923.1.

3D structure databases

HSSPHSSP built from PDB template 1QAY based on UniProtKB P13702.
ProteinModelPortalQ8NUR9.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ8NUR9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTAT00000025870; EBSTAP00000024909; EBSTAG00000025869.
GeneID1004602.
GenomeReviewsGene locus MW2466 in contig BA000033_GR.
KEGGsam:MW2466.
PATRIC19571674. VBIStaAur44266_2548.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1257.
GeneTreeEBGT00050000024128.
HOGENOMHBG477902.
OMANNKGIMN.
PhylomeDBQ8NUR9.
ProtClustDBCLSK886059.

Enzyme and pathway databases

BioCycSAUR196620:MW2466-MONOMER.

Family and domain databases

InterProIPR002202. HMG_CoA_Rdtase.
IPR004553. HMG_CoA_Rdtase_bac-typ.
IPR023074. HMG_CoA_Rdtase_cat.
IPR023076. HMG_CoA_Rdtase_CS.
IPR009023. HMG_CoA_Rdtase_NAD(P)-bd.
IPR009029. HMG_CoA_Rdtase_sub-bd.
[Graphical view]
Gene3DG3DSA:3.30.70.420. G3DSA:3.30.70.420. 1 hit.
G3DSA:3.90.770.10. HMG-CoA_red. 2 hits.
KOK00054.
PfamPF00368. HMG-CoA_red. 1 hit.
[Graphical view]
PRINTSPR00071. HMGCOARDTASE.
SUPFAMSSF55035. HMG_CoA_NAD_bind. 1 hit.
SSF56542. HMG_CoA_sub_bind. 1 hit.
TIGRFAMsTIGR00532. HMG_CoA_R_NAD. 1 hit.
PROSITEPS00066. HMG_COA_REDUCTASE_1. 1 hit.
PS01192. HMG_COA_REDUCTASE_3. 1 hit.
PS50065. HMG_COA_REDUCTASE_4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ8NUR9_STAAW
AccessionPrimary (citable) accession number: Q8NUR9
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: December 14, 2011
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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