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Protein

Probable serine/threonine-protein kinase PknB

Gene

pknB

Organism
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei38 – 381ATPPROSITE-ProRule annotation
Active sitei136 – 1361Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 239ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. penicillin binding Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCGLU196627:GJDM-45-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase PknB (EC:2.7.11.1)
Gene namesi
Name:pknB
Ordered Locus Names:Cgl0041, cg0057
OrganismiCorynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Taxonomic identifieri196627 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000000582: Chromosome, UP000001009: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 646646Probable serine/threonine-protein kinase PknBPRO_0000171197Add
BLAST

Interactioni

Protein-protein interaction databases

DIPiDIP-48321N.
STRINGi196627.cg0057.

Structurei

3D structure databases

ProteinModelPortaliQ8NU98.
SMRiQ8NU98. Positions 5-278.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini9 – 278270Protein kinasePROSITE-ProRule annotationAdd
BLAST
Domaini365 – 43167PASTA 1PROSITE-ProRule annotationAdd
BLAST
Domaini432 – 50069PASTA 2PROSITE-ProRule annotationAdd
BLAST
Domaini501 – 56565PASTA 3PROSITE-ProRule annotationAdd
BLAST
Domaini570 – 63869PASTA 4PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 4 PASTA domains.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037185.
KOiK08884.
OMAiPANIMIN.
OrthoDBiEOG6B35XT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 4 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 3 hits.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8NU98-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTFVIADRYE LDAVIGSGGM SEVFAATDTL IGREVAVKML RIDLAKDPNF
60 70 80 90 100
RERFRREAQN SGRLSHSSIV AVFDTGEVDK DGTSVPYIVM ERVQGRNLRE
110 120 130 140 150
VVTEDGVFTP VEAANILIPV CEALQASHDA GIIHRDVKPA NIMITNTGGV
160 170 180 190 200
KVMDFGIARA VNDSTSAMTQ TSAVIGTAQY LSPEQARGKP ADARSDIYAT
210 220 230 240 250
GCVMYELVTG KPPFEGESPF AVAYQHVQED PTPPSDFIAD LTPTSAVNVD
260 270 280 290 300
AVVLTAMAKH PADRYQTASE MAADLGRLSR NAVSHAARAH VETEETPEEP
310 320 330 340 350
ETRFSTRTST QVAPAAGVAA ASTGSGSSSR KRGSRGLTAL AIVLSLGVVG
360 370 380 390 400
VAGAFTYDYF ANSSSTATSA IPNVEGLPQQ EALTELQAAG FVVNIVEEAS
410 420 430 440 450
ADVAEGLVIR ANPSVGSEIR QGATVTITVS TGREMINIPD VSGMTLEDAA
460 470 480 490 500
RALEDVGLIL NQNVREETSD DVESGLVIDQ NPEAGQEVVV GSSVSLTMSS
510 520 530 540 550
GTESIRVPNL TGMNWSQAEQ NLISMGFNPT ASYLDSSEPE GEVLSVSSQG
560 570 580 590 600
TELPKGSSIT VEVSNGMLIQ APDLARMSTE QAISALRAAG WTAPDQSLIV
610 620 630 640
GDPIHTAALV DQNKIGFQSP TPATLFRKDA QVQVRLFEFD LAALVQ
Length:646
Mass (Da):68,237
Last modified:October 1, 2002 - v1
Checksum:i0F3B4980ECF73BFB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000036 Genomic DNA. Translation: BAB97434.1.
BX927148 Genomic DNA. Translation: CAF18609.1.
RefSeqiNP_599293.1. NC_003450.3.
WP_011013340.1. NC_006958.1.
YP_224338.1. NC_006958.1.

Genome annotation databases

EnsemblBacteriaiBAB97434; BAB97434; BAB97434.
CAF18609; CAF18609; cg0057.
GeneIDi1021362.
3344986.
KEGGicgb:cg0057.
cgl:NCgl0040.
PATRICi21492118. VBICorGlu203724_0042.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000036 Genomic DNA. Translation: BAB97434.1.
BX927148 Genomic DNA. Translation: CAF18609.1.
RefSeqiNP_599293.1. NC_003450.3.
WP_011013340.1. NC_006958.1.
YP_224338.1. NC_006958.1.

3D structure databases

ProteinModelPortaliQ8NU98.
SMRiQ8NU98. Positions 5-278.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-48321N.
STRINGi196627.cg0057.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB97434; BAB97434; BAB97434.
CAF18609; CAF18609; cg0057.
GeneIDi1021362.
3344986.
KEGGicgb:cg0057.
cgl:NCgl0040.
PATRICi21492118. VBICorGlu203724_0042.

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037185.
KOiK08884.
OMAiPANIMIN.
OrthoDBiEOG6B35XT.

Enzyme and pathway databases

BioCyciCGLU196627:GJDM-45-MONOMER.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 4 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 3 hits.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The Corynebacterium glutamicum genome: features and impacts on biotechnological processes."
    Ikeda M., Nakagawa S.
    Appl. Microbiol. Biotechnol. 62:99-109(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

Entry informationi

Entry nameiPKN1_CORGL
AccessioniPrimary (citable) accession number: Q8NU98
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: October 1, 2002
Last modified: March 4, 2015
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.