Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q8NU98 (PKN1_CORGL) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable serine/threonine-protein kinase PknB

EC=2.7.11.1
Gene names
Name:pknB
Ordered Locus Names:Cgl0041, cg0057
OrganismCorynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025) [Reference proteome] [HAMAP]
Taxonomic identifier196627 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length646 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 4 PASTA domains.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 646646Probable serine/threonine-protein kinase PknB
PRO_0000171197

Regions

Domain9 – 278270Protein kinase
Domain365 – 43167PASTA 1
Domain432 – 50069PASTA 2
Domain501 – 56565PASTA 3
Domain570 – 63869PASTA 4
Nucleotide binding15 – 239ATP By similarity

Sites

Active site1361Proton acceptor By similarity
Binding site381ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8NU98 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 0F3B4980ECF73BFB

FASTA64668,237
        10         20         30         40         50         60 
MTFVIADRYE LDAVIGSGGM SEVFAATDTL IGREVAVKML RIDLAKDPNF RERFRREAQN 

        70         80         90        100        110        120 
SGRLSHSSIV AVFDTGEVDK DGTSVPYIVM ERVQGRNLRE VVTEDGVFTP VEAANILIPV 

       130        140        150        160        170        180 
CEALQASHDA GIIHRDVKPA NIMITNTGGV KVMDFGIARA VNDSTSAMTQ TSAVIGTAQY 

       190        200        210        220        230        240 
LSPEQARGKP ADARSDIYAT GCVMYELVTG KPPFEGESPF AVAYQHVQED PTPPSDFIAD 

       250        260        270        280        290        300 
LTPTSAVNVD AVVLTAMAKH PADRYQTASE MAADLGRLSR NAVSHAARAH VETEETPEEP 

       310        320        330        340        350        360 
ETRFSTRTST QVAPAAGVAA ASTGSGSSSR KRGSRGLTAL AIVLSLGVVG VAGAFTYDYF 

       370        380        390        400        410        420 
ANSSSTATSA IPNVEGLPQQ EALTELQAAG FVVNIVEEAS ADVAEGLVIR ANPSVGSEIR 

       430        440        450        460        470        480 
QGATVTITVS TGREMINIPD VSGMTLEDAA RALEDVGLIL NQNVREETSD DVESGLVIDQ 

       490        500        510        520        530        540 
NPEAGQEVVV GSSVSLTMSS GTESIRVPNL TGMNWSQAEQ NLISMGFNPT ASYLDSSEPE 

       550        560        570        580        590        600 
GEVLSVSSQG TELPKGSSIT VEVSNGMLIQ APDLARMSTE QAISALRAAG WTAPDQSLIV 

       610        620        630        640 
GDPIHTAALV DQNKIGFQSP TPATLFRKDA QVQVRLFEFD LAALVQ 

« Hide

References

[1]"The Corynebacterium glutamicum genome: features and impacts on biotechnological processes."
Ikeda M., Nakagawa S.
Appl. Microbiol. Biotechnol. 62:99-109(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
[2]"The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins."
Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F., Moeckel B. expand/collapse author list , Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O., Sahm H., Wendisch V.F., Wiegraebe I., Tauch A.
J. Biotechnol. 104:5-25(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000036 Genomic DNA. Translation: BAB97434.1.
BX927148 Genomic DNA. Translation: CAF18609.1.
RefSeqNP_599293.1. NC_003450.3.
YP_224338.1. NC_006958.1.

3D structure databases

ProteinModelPortalQ8NU98.
SMRQ8NU98. Positions 5-278.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-48321N.
STRING196627.cg0057.

PTM databases

PhosSiteP0904605.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB97434; BAB97434; BAB97434.
CAF18609; CAF18609; cg0057.
GeneID1021362.
3344986.
KEGGcgb:cg0057.
cgl:NCgl0040.
PATRIC21492118. VBICorGlu203724_0042.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000037185.
KOK08884.
OMATGKDPGT.
OrthoDBEOG6B35XT.
ProtClustDBCLSK632622.

Enzyme and pathway databases

BioCycCGLU196627:GJDM-45-MONOMER.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR005543. PASTA.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF03793. PASTA. 4 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00740. PASTA. 3 hits.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKN1_CORGL
AccessionPrimary (citable) accession number: Q8NU98
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: October 1, 2002
Last modified: November 13, 2013
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families