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Q8NU98

- PKN1_CORGL

UniProt

Q8NU98 - PKN1_CORGL

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Protein
Probable serine/threonine-protein kinase PknB
Gene
pknB, Cgl0041, cg0057
Organism
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei38 – 381ATP By similarity
Active sitei136 – 1361Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 239ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. penicillin binding Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCGLU196627:GJDM-45-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase PknB (EC:2.7.11.1)
Gene namesi
Name:pknB
Ordered Locus Names:Cgl0041, cg0057
OrganismiCorynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Taxonomic identifieri196627 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000000582: Chromosome, UP000001009: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 646646Probable serine/threonine-protein kinase PknB
PRO_0000171197Add
BLAST

PTM databases

PhosSiteiP0904605.

Interactioni

Protein-protein interaction databases

DIPiDIP-48321N.
STRINGi196627.cg0057.

Structurei

3D structure databases

ProteinModelPortaliQ8NU98.
SMRiQ8NU98. Positions 5-278.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini9 – 278270Protein kinase
Add
BLAST
Domaini365 – 43167PASTA 1
Add
BLAST
Domaini432 – 50069PASTA 2
Add
BLAST
Domaini501 – 56565PASTA 3
Add
BLAST
Domaini570 – 63869PASTA 4
Add
BLAST

Sequence similaritiesi

Contains 4 PASTA domains.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037185.
KOiK08884.
OMAiMSKNPAN.
OrthoDBiEOG6B35XT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 4 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 3 hits.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8NU98-1 [UniParc]FASTAAdd to Basket

« Hide

MTFVIADRYE LDAVIGSGGM SEVFAATDTL IGREVAVKML RIDLAKDPNF    50
RERFRREAQN SGRLSHSSIV AVFDTGEVDK DGTSVPYIVM ERVQGRNLRE 100
VVTEDGVFTP VEAANILIPV CEALQASHDA GIIHRDVKPA NIMITNTGGV 150
KVMDFGIARA VNDSTSAMTQ TSAVIGTAQY LSPEQARGKP ADARSDIYAT 200
GCVMYELVTG KPPFEGESPF AVAYQHVQED PTPPSDFIAD LTPTSAVNVD 250
AVVLTAMAKH PADRYQTASE MAADLGRLSR NAVSHAARAH VETEETPEEP 300
ETRFSTRTST QVAPAAGVAA ASTGSGSSSR KRGSRGLTAL AIVLSLGVVG 350
VAGAFTYDYF ANSSSTATSA IPNVEGLPQQ EALTELQAAG FVVNIVEEAS 400
ADVAEGLVIR ANPSVGSEIR QGATVTITVS TGREMINIPD VSGMTLEDAA 450
RALEDVGLIL NQNVREETSD DVESGLVIDQ NPEAGQEVVV GSSVSLTMSS 500
GTESIRVPNL TGMNWSQAEQ NLISMGFNPT ASYLDSSEPE GEVLSVSSQG 550
TELPKGSSIT VEVSNGMLIQ APDLARMSTE QAISALRAAG WTAPDQSLIV 600
GDPIHTAALV DQNKIGFQSP TPATLFRKDA QVQVRLFEFD LAALVQ 646
Length:646
Mass (Da):68,237
Last modified:October 1, 2002 - v1
Checksum:i0F3B4980ECF73BFB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000036 Genomic DNA. Translation: BAB97434.1.
BX927148 Genomic DNA. Translation: CAF18609.1.
RefSeqiNP_599293.1. NC_003450.3.
WP_011013340.1. NC_006958.1.
YP_224338.1. NC_006958.1.

Genome annotation databases

EnsemblBacteriaiBAB97434; BAB97434; BAB97434.
CAF18609; CAF18609; cg0057.
GeneIDi1021362.
KEGGicgb:cg0057.
cgl:NCgl0040.
PATRICi21492118. VBICorGlu203724_0042.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000036 Genomic DNA. Translation: BAB97434.1 .
BX927148 Genomic DNA. Translation: CAF18609.1 .
RefSeqi NP_599293.1. NC_003450.3.
WP_011013340.1. NC_006958.1.
YP_224338.1. NC_006958.1.

3D structure databases

ProteinModelPortali Q8NU98.
SMRi Q8NU98. Positions 5-278.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-48321N.
STRINGi 196627.cg0057.

PTM databases

PhosSitei P0904605.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB97434 ; BAB97434 ; BAB97434 .
CAF18609 ; CAF18609 ; cg0057 .
GeneIDi 1021362.
KEGGi cgb:cg0057.
cgl:NCgl0040.
PATRICi 21492118. VBICorGlu203724_0042.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000037185.
KOi K08884.
OMAi MSKNPAN.
OrthoDBi EOG6B35XT.

Enzyme and pathway databases

BioCyci CGLU196627:GJDM-45-MONOMER.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF03793. PASTA. 4 hits.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00740. PASTA. 3 hits.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The Corynebacterium glutamicum genome: features and impacts on biotechnological processes."
    Ikeda M., Nakagawa S.
    Appl. Microbiol. Biotechnol. 62:99-109(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

Entry informationi

Entry nameiPKN1_CORGL
AccessioniPrimary (citable) accession number: Q8NU98
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: October 1, 2002
Last modified: September 3, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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