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Q8NU97 (PKN2_CORGL) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinases PknA

EC=2.7.11.1
Gene names
Name:pknA
Synonyms:drp72
Ordered Locus Names:Cgl0042, cg0059
OrganismCorynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025) [Reference proteome] [HAMAP]
Taxonomic identifier196627 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length469 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Sequence caution

The sequence BAB88662.1 differs from that shown. Reason: Frameshift at position 348.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 469469Serine/threonine-protein kinases PknA
PRO_0000171199

Regions

Domain20 – 281262Protein kinase
Nucleotide binding26 – 349ATP By similarity
Compositional bias354 – 44087Thr-rich

Sites

Active site1481Proton acceptor By similarity
Binding site491ATP By similarity

Experimental info

Sequence conflict1191R → S in BAB88662. Ref.1
Sequence conflict1431D → N in BAB88662. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q8NU97 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 53C10AD97BB95595

FASTA46950,375
        10         20         30         40         50         60 
MSQEDITGKD RLQELIGADY RLQWIIGHGG MSTVWLADDV VNDREVAIKV LRPEFSDNQE 

        70         80         90        100        110        120 
FLNRFRNEAQ AAENIDSEHV VATYDYREVP DPAGHTFCFI VMEFVRGESL ADLLEREGRL 

       130        140        150        160        170        180 
PEDLALDVME QAAHGLSVIH RMDMVHRDIK PGNMLITANG IVKITDFGIA KAAAAVPLTR 

       190        200        210        220        230        240 
TGMVVGTAQY VSPEQAQGKE VTAASDIYSL GVVGYEMMAG RRPFTGDSSV SVAIAHINQA 

       250        260        270        280        290        300 
PPQMPTSISA QTRELIGIAL RKDPGRRFPD GNEMALAVSA VRLGKRPPQP RTSAMMAQAE 

       310        320        330        340        350        360 
APSPSESTAM LGRVARPATI TQEAAPKRGS GIGIGLFIAA LLAVIIGAVI YAGTTGILFN 

       370        380        390        400        410        420 
DTPEETTTPE TITETYTPTV EETTSQWVPP TPPTRSTFTE PETTSHRPTT SEESTSEEPT 

       430        440        450        460 
TEAPTSSRTV PQIPTSTPRT SASVPVETNA PADDLIDAVN GLLDVGGAQ 

« Hide

References

« Hide 'large scale' references
[1]"drp72 of Corynebacterium glutamicum."
Hirano S., Kimura E., Kawahara Y., Sugimoto S.
Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The Corynebacterium glutamicum genome: features and impacts on biotechnological processes."
Ikeda M., Nakagawa S.
Appl. Microbiol. Biotechnol. 62:99-109(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
[3]"The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins."
Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F., Moeckel B. expand/collapse author list , Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O., Sahm H., Wendisch V.F., Wiegraebe I., Tauch A.
J. Biotechnol. 104:5-25(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB083046 Genomic DNA. Translation: BAB88662.1. Frameshift.
BA000036 Genomic DNA. Translation: BAB97435.1.
BX927148 Genomic DNA. Translation: CAF18610.1.
RefSeqNP_599294.1. NC_003450.3.
YP_224339.1. NC_006958.1.

3D structure databases

ProteinModelPortalQ8NU97.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-48320N.
STRING196627.cg0059.

PTM databases

PhosSiteP0904601.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB97435; BAB97435; BAB97435.
CAF18610; CAF18610; cg0059.
GeneID1021413.
KEGGcgb:cg0059.
cgl:NCgl0041.
PATRIC21492120. VBICorGlu203724_0043.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000037187.
KOK08884.
OMAHGGMSTV.
OrthoDBEOG6B35XT.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 2 hits.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKN2_CORGL
AccessionPrimary (citable) accession number: Q8NU97
Secondary accession number(s): Q8RQP0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: October 1, 2002
Last modified: July 9, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families