Reviewed, UniProtKB/Swiss-Prot Q8NTC4 (DEOC_CORGL)

Names and origin

Protein names

Recommended name:
    Deoxyribose-phosphate aldolase
    EC=4.1.2.4
Alternative name(s):
    Phosphodeoxyriboaldolase
      Short name=Deoxyriboaldolase
      Short name=DERA

Gene names

Name:	deoC
Ordered Locus Names:	Cgl0383, cg0458

Organism

Corynebacterium glutamicum (Brevibacterium flavum) [Complete proteome] [HAMAP]

Taxonomic identifier

1718 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	222 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Schiff base
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 222	222	Deoxyribose-phosphate aldolase HAMAP MF_00114		PRO_0000057230
Sites
	Active site	156	1	Schiff-base intermediate with acetaldehyde By similarity
	Active site	186	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8NTC4-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 563C3D6B6805DD08	FASTA	222	22,520
	10 20 30 40 50 60 MTISRSTMAQ ILDYTLLGPE VTNSELAAFI DSAIELGVGT ICVPNSMVNL TAKAQEAGIR 70 80 90 100 110 120 VATVAGFPHG KTPALVKAAE ARLAVQSGAS EVDVVLDIAV VKEGDANRLL QEIVAIREAV 130 140 150 160 170 180 PSPVVLKFIL ETAVVSDEAI VTAVNALIAA GADFAKTSTG FHPAGGATVE AVRVMASASR 190 200 210 220 GRVGIKAAGG VKTWEDAVAF VEAGATRIGT SNAGAILEGA PE

References

[1]

"Complete genomic sequence of Corynebacterium glutamicum ATCC 13032." Nakagawa S. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

[2]

"The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins." Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F., Moeckel B. , Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O., Sahm H., Wendisch V.F., Wiegraebe I., Tauch A. J. Biotechnol. 104:5-25(2003) [PubMed: 12948626] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000036 Genomic DNA. Translation: BAB97776.1. BX927149 Genomic DNA. Translation: CAF19098.1.
RefSeq	NP_599631.1. YP_224684.1.
3D structure databases
HSSP	HSSP built from PDB template 1MZH based on UniProtKB O66540.
ModBase	Search...
Genome annotation databases
GeneID	1021418. 3344707.
GenomeReviews	Gene locus Cgl0383 in contig BA000036_GR. Gene locus cg0458 in contig BX927147_GR.
KEGG	cgb:cg0458. cgl:NCgl0372.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8NTC4.
OMA	Q8NTC4. EEKIAMC.
Enzyme and pathway databases
BioCyc	CGLU196627-1:CG0458-MON.
BRENDA	4.1.2.4. 812.
Family and domain databases
HAMAP	MF_00114. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. deoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DEOC_CORGL

Accession

Primary (citable) accession number: Q8NTC4

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 2002
Last sequence update:	October 1, 2002
Last modified:	June 16, 2009
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)