Q8NSS4 (GCP_CORGL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	Cgl0594, cg0687

Organism

Corynebacterium glutamicum (Brevibacterium flavum)

Taxonomic identifier

1718 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	344 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 344	344	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303338

Sequences

	Sequence		Length	Mass (Da)
	Q8NSS4 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: B48A5C6345B58444	FASTA	344	35,887
	10 20 30 40 50 60 MIVLGIESSC DETGVGVVKL DGEGNLEILA DSVASSMQEH ARFGGVVPEI ASRAHLESMV 70 80 90 100 110 120 PVMREALRQA GVDRPDAVAA TVGPGLAGAL LVGASAAKAY AAAWGVPFYA VNHLGGHVAV 130 140 150 160 170 180 ANLEGETLPH AVALLVSGGH TQLLEVDAVG LPMKELGSTL DDAAGEAYDK VSRLLGLGYP 190 200 210 220 230 240 GGPIIDKLAR RGNPEAIAFP RGLMKKSDSR HDFSFSGLKT SVARYVEAAE RNGEVISVED 250 260 270 280 290 300 VCASFQEAVC DVLTFKAVRA CRDVGAKVLL LGGGVAANSR LRELAQERCD KADIELRVPR 310 320 330 340 FNLCTDNGVM IAALAAQRIH EGAQESPISV GTDPSLSVET PQVF

References

[1]

"Complete genomic sequence of Corynebacterium glutamicum ATCC 13032." Nakagawa S. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

[2]

"The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins." Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F., Moeckel B. , Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O., Sahm H., Wendisch V.F., Wiegraebe I., Tauch A. J. Biotechnol. 104:5-25(2003) [PubMed: 12948626] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000036 Genomic DNA. Translation: BAB97987.1. BX927149 Genomic DNA. Translation: CAF19299.1.
RefSeq	NP_599830.1. NC_003450.3. YP_224885.1. NC_006958.1.
3D structure databases
ProteinModelPortal	Q8NSS4.
ModBase	Search...
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1018598. 3344383.
GenomeReviews	Gene locus Cgl0594 in contig BA000036_GR. Gene locus cg0687 in contig BX927147_GR.
KEGG	cgb:cg0687.
PATRIC	21493238. VBICorGlu203724_0585.
Phylogenomic databases
HOGENOM	HBG304663.
OMA	PLYGVNH.
PhylomeDB	Q8NSS4.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	CGLU196627:CG0687-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_CORGL

Accession

Primary (citable) accession number: Q8NSS4
Secondary accession number(s): Q6M7G9

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	October 1, 2002
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program