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Protein

Methionine import ATP-binding protein MetN

Gene

metN

Organism
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi62 – 698ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Amino-acid transport, Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Protein family/group databases

TCDBi3.A.1.24.4. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Methionine import ATP-binding protein MetNUniRule annotation (EC:3.6.3.-UniRule annotation)
Gene namesi
Name:metNUniRule annotation
Ordered Locus Names:Cgl0636, cg0736
OrganismiCorynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Taxonomic identifieri196627 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
Proteomesi
  • UP000000582 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 360360Methionine import ATP-binding protein MetNPRO_0000270288Add
BLAST

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ).UniRule annotation

Protein-protein interaction databases

STRINGi196627.cg0736.

Structurei

3D structure databases

ProteinModelPortaliQ8NSN2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini25 – 265241ABC transporterUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. [View classification]UniRule annotation
Contains 1 ABC transporter domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108JEI. Bacteria.
COG1135. LUCA.
KOiK02071.
OMAiLRTINRK.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR026253. ABC_MetN.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR017908. ABC_transprt_methionine_MetN_C.
IPR018449. NIL_domain.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24220:SF549. PTHR24220:SF549. 1 hit.
PfamiPF00005. ABC_tran. 1 hit.
PF09383. NIL. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00930. NIL. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51264. METN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8NSN2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHTASTPTP EEYSAQQPST QGTRVEFRGI TKVFSNNKSA KTTALDNVTL
60 70 80 90 100
TVEPGEVIGI IGYSGAGKST LVRLINGLDS PTSGSLLLNG TDIVGMPESK
110 120 130 140 150
LRKLRSNIGM IFQQFNLFQS RTAAGNVEYP LEVAKMDKAA RKARVQEMLE
160 170 180 190 200
FVGLGDKGKN YPEQLSGGQK QRVGIARALA TNPTLLLADE ATSALDPETT
210 220 230 240 250
HEVLELLRKV NRELGITIVV ITHEMEVVRS IADKVAVMES GKVVEYGSVY
260 270 280 290 300
EVFSNPQTQV AQKFVATALR NTPDQVESED LLSHEGRLFT IDLTETSGFF
310 320 330 340 350
AATARAAEQG AFVNIVHGGV TTLQRQSFGK MTVRLTGNTA AIEEFYQTLT
360
KTTTIKEITR
Length:360
Mass (Da):39,103
Last modified:October 1, 2002 - v1
Checksum:i75D17F34D0DD4DA5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000036 Genomic DNA. Translation: BAB98029.1.
BX927149 Genomic DNA. Translation: CAF19343.1.
RefSeqiNP_599870.1. NC_003450.3.
WP_003854632.1. NC_006958.1.

Genome annotation databases

EnsemblBacteriaiBAB98029; BAB98029; BAB98029.
CAF19343; CAF19343; cg0736.
GeneIDi1018638.
KEGGicgb:cg0736.
cgl:NCgl0609.
PATRICi21493312. VBICorGlu203724_0622.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000036 Genomic DNA. Translation: BAB98029.1.
BX927149 Genomic DNA. Translation: CAF19343.1.
RefSeqiNP_599870.1. NC_003450.3.
WP_003854632.1. NC_006958.1.

3D structure databases

ProteinModelPortaliQ8NSN2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi196627.cg0736.

Protein family/group databases

TCDBi3.A.1.24.4. the atp-binding cassette (abc) superfamily.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB98029; BAB98029; BAB98029.
CAF19343; CAF19343; cg0736.
GeneIDi1018638.
KEGGicgb:cg0736.
cgl:NCgl0609.
PATRICi21493312. VBICorGlu203724_0622.

Phylogenomic databases

eggNOGiENOG4108JEI. Bacteria.
COG1135. LUCA.
KOiK02071.
OMAiLRTINRK.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR026253. ABC_MetN.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR017908. ABC_transprt_methionine_MetN_C.
IPR018449. NIL_domain.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24220:SF549. PTHR24220:SF549. 1 hit.
PfamiPF00005. ABC_tran. 1 hit.
PF09383. NIL. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00930. NIL. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51264. METN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMETN_CORGL
AccessioniPrimary (citable) accession number: Q8NSN2
Secondary accession number(s): Q6M7C8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: October 1, 2002
Last modified: September 7, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.