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Q8NS31

- G6PI_CORGL

UniProt

Q8NS31 - G6PI_CORGL

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Protein
Glucose-6-phosphate isomerase
Gene
pgi, Cgl0851, cg0973
Organism
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei351 – 3511Proton donor By similarity
Active sitei382 – 3821 By similarity
Active sitei506 – 5061 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:Cgl0851, cg0973
OrganismiCorynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Taxonomic identifieri196627 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000000582: Chromosome, UP000001009: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 540540Glucose-6-phosphate isomeraseUniRule annotation
PRO_0000180633Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi196627.cg0973.

Structurei

3D structure databases

ProteinModelPortaliQ8NS31.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiMIALTHY.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8NS31-1 [UniParc]FASTAAdd to Basket

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MADISTTQVW QDLTDHYSNF QATTLRELFK EENRAEKYTF SAAGLHVDLS    50
KNLLDDATLT KLLALTEESG LRERIDAMFA GEHLNNTEDR AVLHTALRLP 100
AEADLSVDGQ DVAADVHEVL GRMRDFATAL RSGNWLGHTG HTIKKIVNIG 150
IGGSDLGPAM ATKALRAYAT AGISAEFVSN VDPADLVSVL EDLDAESTLF 200
VIASKTFTTQ ETLSNARAAR AWLVEKLGEE AVAKHFVAVS TNAEKVAEFG 250
IDTDNMFGFW DWVGGRYSVD SAVGLSLMAV IGPRDFMRFL GGFHAMDEHF 300
RTTKFEENVP ILMALLGVWY SDFYGAETHA VLPYSEDLSR FAAYLQQLTM 350
ESNGKSVHRD GSPVSTGTGE IYWGEPGTNG QHAFFQLIHQ GTRLVPADFI 400
GFARPKQDLP AGERTMHDLL MSNFFAQTKV LAFGKNAEEI AAEGVAPELV 450
NHKVMPGNRP TTTILAEELT PSILGALIAL YEHIVMVQGV IWDINSFDQW 500
GVELGKQQAN DLAPAVSGEE DVDSGDSSTD SLIKWYRANR 540
Length:540
Mass (Da):59,166
Last modified:October 10, 2002 - v1
Checksum:iFF5866693365EC69
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000036 Genomic DNA. Translation: BAB98244.1.
BX927150 Genomic DNA. Translation: CAF19557.1.
RefSeqiNP_600080.1. NC_003450.3.
YP_225143.1. NC_006958.1.

Genome annotation databases

EnsemblBacteriaiBAB98244; BAB98244; BAB98244.
CAF19557; CAF19557; cg0973.
GeneIDi1018846.
KEGGicgb:cg0973.
cgl:NCgl0817.
PATRICi21493754. VBICorGlu203724_0836.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000036 Genomic DNA. Translation: BAB98244.1 .
BX927150 Genomic DNA. Translation: CAF19557.1 .
RefSeqi NP_600080.1. NC_003450.3.
YP_225143.1. NC_006958.1.

3D structure databases

ProteinModelPortali Q8NS31.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 196627.cg0973.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB98244 ; BAB98244 ; BAB98244 .
CAF19557 ; CAF19557 ; cg0973 .
GeneIDi 1018846.
KEGGi cgb:cg0973.
cgl:NCgl0817.
PATRICi 21493754. VBICorGlu203724_0836.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi MIALTHY.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The Corynebacterium glutamicum genome: features and impacts on biotechnological processes."
    Ikeda M., Nakagawa S.
    Appl. Microbiol. Biotechnol. 62:99-109(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

Entry informationi

Entry nameiG6PI_CORGL
AccessioniPrimary (citable) accession number: Q8NS31
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: October 10, 2002
Last modified: July 9, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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