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Q8NRZ6 (PMT_CORGL) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable dolichyl-phosphate-mannose--protein mannosyltransferase

EC=2.4.1.109
Gene names
Name:pmt
Ordered Locus Names:Cgl0890, cg1014
OrganismCorynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025) [Reference proteome] [HAMAP]
Taxonomic identifier196627 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length520 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins By similarity.

Catalytic activity

Dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein.

Pathway

Protein modification; protein glycosylation.

Subcellular location

Cell membrane; Multi-pass membrane protein Potential.

Disruption phenotype

Loss of protein glycosylation. Ref.3

Sequence similarities

Belongs to the glycosyltransferase 39 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 520520Probable dolichyl-phosphate-mannose--protein mannosyltransferase
PRO_0000421157

Regions

Transmembrane38 – 5821Helical; Potential
Transmembrane119 – 13921Helical; Potential
Transmembrane145 – 16521Helical; Potential
Transmembrane168 – 18821Helical; Potential
Transmembrane237 – 25721Helical; Potential
Transmembrane274 – 29421Helical; Potential
Transmembrane388 – 40821Helical; Potential
Transmembrane418 – 43821Helical; Potential
Transmembrane441 – 46121Helical; Potential
Transmembrane485 – 50521Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q8NRZ6 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 9F6C21ED4B20788D

FASTA52058,734
        10         20         30         40         50         60 
MSQALPVRDQ GRDQGIFAGT LPPAPPKFKW TRLDTYTWAI IAVFALVTRF TGLSSATASG 

        70         80         90        100        110        120 
TPVFDEKHYV PQAWDMVRSW INPITGGIES NPGYGLVVHP PLAKQLEALG EWVFGYTPLG 

       130        140        150        160        170        180 
WRIMVAIFGT LTIFAIMAIA RRLSGSTMVT FIAGILALAD GVLLVSSRFG MLDIFLVFFI 

       190        200        210        220        230        240 
TAAAWALIRD HQQMHQRLND LLLTNGQITK DFGPRFGFRW WRFTTGVFLG LALSVKWSGL 

       250        260        270        280        290        300 
YYIAFFGLTS VFLDLWLRKR YGVRRYVTGT LKNDVIPALG SLVIIPALLY IWSWRAWFAS 

       310        320        330        340        350        360 
ETSVYRHAKT DGTITEDSIL QLFPESIAGW IHYHISVLEF HGSLTTSSGH SHPWDSKPWA 

       370        380        390        400        410        420 
WLVSGRPILY FSSTDISCDV GGTCRRMIYL FGTPAIWWLT VPVILWALWS FFARRSRGYV 

       430        440        450        460        470        480 
VPLVAFAAGF LPWLAAYDRQ MYFFYATALV PFTIIMLALA CGELWGRGKM TPTGLTRGSM 

       490        500        510        520 
AVVTYISLVV MMFLAFSPLF YGFVIPDYVY ESLMWFPSWR 

« Hide

References

« Hide 'large scale' references
[1]"The Corynebacterium glutamicum genome: features and impacts on biotechnological processes."
Ikeda M., Nakagawa S.
Appl. Microbiol. Biotechnol. 62:99-109(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
[2]"The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins."
Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F., Moeckel B. expand/collapse author list , Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O., Sahm H., Wendisch V.F., Wiegraebe I., Tauch A.
J. Biotechnol. 104:5-25(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
[3]"The Corynebacterium glutamicum gene pmt encoding a glycosyltransferase related to eukaryotic protein-O-mannosyltransferases is essential for glycosylation of the resuscitation promoting factor (Rpf2) and other secreted proteins."
Mahne M., Tauch A., Puhler A., Kalinowski J.
FEMS Microbiol. Lett. 259:226-233(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: DISRUPTION PHENOTYPE.
Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000036 Genomic DNA. Translation: BAB98283.1.
BX927150 Genomic DNA. Translation: CAF19596.1.
RefSeqNP_600117.1. NC_003450.3.
YP_225182.1. NC_006958.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING196627.cg1014.

Protocols and materials databases

DNASU1018883.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB98283; BAB98283; BAB98283.
CAF19596; CAF19596; cg1014.
GeneID1018883.
3343200.
KEGGcgb:cg1014.
cgl:NCgl0854.
PATRIC21493828. VBICorGlu203724_0873.

Phylogenomic databases

HOGENOMHOG000097888.
OMAVIYDVHA.
OrthoDBEOG68M4FH.
ProtClustDBCLSK2502769.

Enzyme and pathway databases

UniPathwayUPA00378.

Family and domain databases

InterProIPR027005. GlyclTrfase_39_like.
IPR003342. Glyco_trans_39.
[Graphical view]
PANTHERPTHR10050. PTHR10050. 1 hit.
PfamPF02366. PMT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePMT_CORGL
AccessionPrimary (citable) accession number: Q8NRZ6
Secondary accession number(s): Q6M6Q4
Entry history
Integrated into UniProtKB/Swiss-Prot: February 6, 2013
Last sequence update: October 1, 2002
Last modified: April 16, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways