Reviewed,
UniProtKB/Swiss-Prot Q8NRV3 (PTH1_CORGL)
Last modified
November 3, 2009.
Version 38.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Peptidyl-tRNA hydrolase 1 Short name=PTH 1 EC=3.1.1.29 | ||||
| Gene names |
| ||||
| Organism | Corynebacterium glutamicum (Brevibacterium flavum) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 1718 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium |
Protein attributes
| Sequence length | 177 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity. |
| Catalytic activity | N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP MF_00083 |
| Subunit structure | Monomer By similarity. |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the PTH family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Molecular function | Hydrolase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | translation Inferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | aminoacyl-tRNA hydrolase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 177 | 177 | Peptidyl-tRNA hydrolase 1 HAMAP MF_00083 | PRO_0000187727 | |||
Sequences
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References
| [1] | "Complete genomic sequence of Corynebacterium glutamicum ATCC 13032." Nakagawa S. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025. |
| [2] | "The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins." Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F., Moeckel B. Tauch A.J. Biotechnol. 104:5-25(2003) [PubMed: 12948626] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025. |
Cross-references
Sequence databases | |
|---|---|
| BA000036 Genomic DNA. Translation: BAB98331.1. BX927150 Genomic DNA. Translation: CAF19645.1. | |
| RefSeq | NP_600166.1. YP_225231.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 2PTH based on UniProtKB P23932. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1018930. 3343697. |
| GenomeReviews | Gene locus Cgl0938 in contig BA000036_GR. Gene locus cg1071 in contig BX927147_GR. |
| KEGG | cgb:cg1071. cgl:NCgl0901. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q8NRV3. |
| OMA | GNPEPQY. |
Enzyme and pathway databases | |
| BioCyc | CGLU196627-1:CG1071-MON. |
| BRENDA | 3.1.1.29. 812. |
Family and domain databases | |
| HAMAP | MF_00083. [Tree] |
| InterPro | IPR001328. Pept_tRNA_hydro. IPR018171. Pept_tRNA_hydro_CS. [Graphical view] |
| Gene3D | G3DSA:3.40.50.1470. Pept_tRNA_hydro. 1 hit. |
| PANTHER | PTHR17224. Pept_tRNA_hydro. 1 hit. |
| Pfam | PF01195. Pept_tRNA_hydro. 1 hit. [Graphical view] |
| ProDom | PD005324. PeptRNAhydrolase. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| TIGRFAMs | TIGR00447. pth. 1 hit. |
| PROSITE | PS01195. PEPT_TRNA_HYDROL_1. 1 hit. PS01196. PEPT_TRNA_HYDROL_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PTH1_CORGL | ||||||||
| Accession | Primary (citable) accession number: Q8NRV3 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

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