ID   COAA_CORGL              Reviewed;         312 AA.
AC   Q8NRQ2;
DT   10-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT   10-OCT-2002, sequence version 1.
DT   16-JUN-2009, entry version 45.
DE   RecName: Full=Pantothenate kinase;
DE            EC=2.7.1.33;
DE   AltName: Full=Pantothenic acid kinase;
GN   Name=coaA; OrderedLocusNames=Cgl0995, cg1132;
OS   Corynebacterium glutamicum (Brevibacterium flavum).
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=1718;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025;
RA   Nakagawa S.;
RT   "Complete genomic sequence of Corynebacterium glutamicum ATCC 13032.";
RL   Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025;
RX   MEDLINE=22830012; PubMed=12948626; DOI=10.1016/S0168-1656(03)00154-8;
RA   Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M.,
RA   Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L.,
RA   Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B.,
RA   McHardy A.C., Meyer F., Moeckel B., Pfefferle W., Puehler A.,
RA   Rey D.A., Rueckert C., Rupp O., Sahm H., Wendisch V.F., Wiegraebe I.,
RA   Tauch A.;
RT   "The complete Corynebacterium glutamicum ATCC 13032 genome sequence
RT   and its impact on the production of L-aspartate-derived amino acids
RT   and vitamins.";
RL   J. Biotechnol. 104:5-25(2003).
CC   -!- CATALYTIC ACTIVITY: ATP + (R)-pantothenate = ADP + (R)-4'-
CC       phosphopantothenate.
CC   -!- PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis; coenzyme
CC       A from pantothenate: step 1/5.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Probable).
CC   -!- SIMILARITY: Belongs to the prokaryotic pantothenate kinase family.
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DR   EMBL; BA000036; BAB98388.1; -; Genomic_DNA.
DR   EMBL; BX927151; CAF19699.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_600220.1; -.
DR   RefSeq; YP_225285.1; -.
DR   HSSP; P15044; 1ESM.
DR   GeneID; 1018982; -.
DR   GeneID; 3342901; -.
DR   GenomeReviews; BA000036_GR; Cgl0995.
DR   GenomeReviews; BX927147_GR; cg1132.
DR   KEGG; cgb:cg1132; -.
DR   KEGG; cgl:NCgl0953; -.
DR   HOGENOM; Q8NRQ2; -.
DR   OMA; Q8NRQ2; PKVDLIT.
DR   BioCyc; CGLU196627-1:CG1132-MON; -.
DR   BRENDA; 2.7.1.33; 812.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004594; F:pantothenate kinase activity; IEA:HAMAP.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00215; -; 1.
DR   InterPro; IPR004566; PanK_bact.
DR   PANTHER; PTHR10285:SF7; PanK_bact; 1.
DR   PIRSF; PIRSF000545; Pantothenate_kin; 1.
DR   TIGRFAMs; TIGR00554; panK_bact; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coenzyme A biosynthesis; Complete proteome; Cytoplasm;
KW   Kinase; Nucleotide-binding; Transferase.
FT   CHAIN         1    312       Pantothenate kinase.
FT                                /FTId=PRO_0000194424.
FT   NP_BIND      97    104       ATP (Potential).
SQ   SEQUENCE   312 AA;  35316 MW;  BBDE9EF3C83F95F6 CRC64;
     MKPSPRTPDF SPYLDFDRAQ WRELRNSMPQ VLTQKEVIEL RGIGENIDLA EVAEVYLPLS
     RLIHLQVAAR QQLTAATETF LGTSPSISVP FVIGVAGSVA VGKSTTARLL QVLLQRWNSH
     PRVDLVTTDG FLYPGAELIR RGLMSRKGFP ESYDQRALLR FVTDVKSGKL EVNAPVYSHT
     AYDRVPGEFT TVRQPDILIV EGLNVLQTGP TLMVSDLFDF SVYVDARTED IEKWYIDRFL
     KLRDTAFRRP GAHFSHYADM ADPESIAVAR ELWQSINLPN LVENILPTRV RASLVLKKGS
     DHLVERVRMR KI
//