Q8NRQ2 (COAA_CORGL) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 61.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Pantothenate kinase EC=2.7.1.33 Alternative name(s): Pantothenic acid kinase | ||||
| Gene names |
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| Organism | Corynebacterium glutamicum (Brevibacterium flavum) | ||||
| Taxonomic identifier | 1718 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium |
Protein attributes
| Sequence length | 312 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate. HAMAP MF_00215 |
| Pathway | Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5. HAMAP MF_00215 |
| Subcellular location | Cytoplasm Probable HAMAP MF_00215. |
| Sequence similarities | Belongs to the prokaryotic pantothenate kinase family. |
| Sequence caution | The sequence CAF19699.1 differs from that shown. Reason: Erroneous initiation. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Coenzyme A biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | coenzyme A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW pantothenate kinase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 312 | 312 | Pantothenate kinase HAMAP MF_00215 | PRO_0000194424 | |||||
Regions | |||||||||
| Nucleotide binding | 97 – 104 | 8 | ATP Potential | ||||||
Sequences
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References
| [1] | "Complete genomic sequence of Corynebacterium glutamicum ATCC 13032." Nakagawa S. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025. |
| [2] | "The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins." Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F., Moeckel B. Tauch A.J. Biotechnol. 104:5-25(2003) [PubMed: 12948626] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BA000036 Genomic DNA. Translation: BAB98388.1. BX927151 Genomic DNA. Translation: CAF19699.1. Different initiation. |
| RefSeq | NP_600220.1. NC_003450.3. YP_225285.1. NC_006958.1. |
3D structure databases | |
| ProteinModelPortal | Q8NRQ2. |
| SMR | Q8NRQ2. Positions 11-312. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 1018982. 3342901. |
| GenomeReviews | Gene locus Cgl0995 in contig BA000036_GR. Gene locus cg1132 in contig BX927147_GR. |
| KEGG | cgb:cg1132. cgl:NCgl0953. |
| PATRIC | 21494040. VBICorGlu203724_0977. |
Phylogenomic databases | |
| HOGENOM | HBG732538. |
| OMA | EVYLPLS. |
| PhylomeDB | Q8NRQ2. |
| ProtClustDB | PRK05439. |
Enzyme and pathway databases | |
| BioCyc | CGLU196627:CG1132-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00215. Pantothen_kinase_1. [Tree] |
| InterPro | IPR004566. PanK_bact. IPR006083. PRK/URK. [Graphical view] |
| KO | K00867. |
| PANTHER | PTHR10285:SF7. PanK_bact. 1 hit. |
| Pfam | PF00485. PRK. 1 hit. [Graphical view] |
| PIRSF | PIRSF000545. Pantothenate_kin. 1 hit. |
| TIGRFAMs | TIGR00554. PanK_bact. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | COAA_CORGL | ||||||||
| Accession | Primary (citable) accession number: Q8NRQ2 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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