Q8NNW4 (ACYP_CORGL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acylphosphatase
EC=3.6.1.7

Alternative name(s):
Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	Cgl2066, cg2266

Organism

Corynebacterium glutamicum (Brevibacterium flavum)

Taxonomic identifier

1718 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	94 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 94	94	Acylphosphatase HAMAP MF_01450		PRO_0000326691
Regions
	Domain	5 – 94	90	Acylphosphatase-like
Sites
	Active site	20	1	By similarity
	Active site	38	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8NNW4 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: AD5EBB6DCBCD4EC7	FASTA	94	10,663
	10 20 30 40 50 60 MEKVRLTAFV HGHVQGVGFR WWTTSQAREL KLAGSASNLS DGRVCVVAEG PQTQCEELLR 70 80 90 RLKENPSSYR RPGHVDTVIE QWGEPRDVEG FVER

References

[1]

"Complete genomic sequence of Corynebacterium glutamicum ATCC 13032." Nakagawa S. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

[2]

"The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins." Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F., Moeckel B. , Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O., Sahm H., Wendisch V.F., Wiegraebe I., Tauch A. J. Biotechnol. 104:5-25(2003) [PubMed: 12948626] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000036 Genomic DNA. Translation: BAB99459.1. BX927154 Genomic DNA. Translation: CAF20403.1.
RefSeq	NP_694659.1. NC_003450.3. YP_226304.1. NC_006958.1.
3D structure databases
HSSP	HSSP built from PDB template 2BJD based on UniProtKB Q97ZL0.
ProteinModelPortal	Q8NNW4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1020019. 3343100.
GenomeReviews	Gene locus Cgl2066 in contig BA000036_GR. Gene locus cg2266 in contig BX927147_GR.
KEGG	cgb:cg2266. cgl:NCgl1987.
PATRIC	21496134. VBICorGlu203724_2003.
Phylogenomic databases
HOGENOM	HBG750266.
OMA	GRVCVVA.
PhylomeDB	Q8NNW4.
ProtClustDB	PRK14422.
Enzyme and pathway databases
BioCyc	CGLU196627:CG2266-MONOMER.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
KO	K01512.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
SUPFAM	SSF54975. Acylphosphatase. 1 hit.
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. False negative. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_CORGL

Accession

Primary (citable) accession number: Q8NNW4
Secondary accession number(s): Q6M3Z7

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	October 1, 2002
Last modified:	January 25, 2012
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program