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Q8NNM2 (Q8NNM2_CORGL) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Methylenetetrahydrofolate reductase RuleBase RU003862
EC=1.5.1.20 RuleBase RU003862
Gene names
Name:metF EMBL CAF20512.1
Ordered Locus Names:cg2383, Cgl2171
OrganismCorynebacterium glutamicum (Brevibacterium flavum)
Taxonomic identifier1718 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length326 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H. RuleBase RU003862

Cofactor

FAD By similarity. RuleBase RU003862

Pathway

One-carbon metabolism; tetrahydrofolate pathway. RuleBase RU004255

Sequence similarities

Belongs to the methylenetetrahydrofolate reductase family. RuleBase RU003862

Sequences

Sequence LengthMass (Da)Tools
Q8NNM2 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 854CE1D473342220

FASTA32636,227
        10         20         30         40         50         60 
MSLTNIPASS QWAISDVLKR PSPGRVPFSV EFMPPRDDAA EERLYRAAEV FHDLGASFVS 

        70         80         90        100        110        120 
VTYGAGGSTR ERTSRIARRL AKQPLTTLVH LTLVNHTREE MKAILREYLE LGLTNLLALR 

       130        140        150        160        170        180 
GDPPGDPLGD WVSTDGGLNY ASELIDLIKS TPEFREFDLG IASFPEGHFR AKTLEEDTKY 

       190        200        210        220        230        240 
TLAKLRGGAE YSITQMFFDV EDYLRLRDRL VAADPIHGAK PIIPGIMPIT SLRSVRRQVE 

       250        260        270        280        290        300 
LSGAQLPSQL EESLVRAANG NEEANKDEIR KVGIEYSTNM AERLIAEGAE DLHFMTLNFT 

       310        320 
RATQEVLYNL GMAPAWGAEH GQDAVR

« Hide

References

[1]"The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins."
Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F., Moeckel B. expand/collapse author list , Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O., Sahm H., Wendisch V.F., Wiegraebe I., Tauch A.
J. Biotechnol. 104:5-25(2003) [PubMed: 12948626] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025 [Kalinowski].
[2]"Complete genomic sequence of Corynebacterium glutamicum ATCC 13032."
Nakagawa S.
Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025 [Nakagawa].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000036 Genomic DNA. Translation: BAB99564.1.
BX927154 Genomic DNA. Translation: CAF20512.1.
RefSeqNP_601375.2. NC_003450.3.
YP_226413.1. NC_006958.1.

3D structure databases

HSSPHSSP built from PDB template 1B5T based on UniProtKB P00394.
ProteinModelPortalQ8NNM2.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1020123.
3345331.
GenomeReviewsGene locus Cgl2171 in contig BA000036_GR.
Gene locus cg2383 in contig BX927147_GR.
KEGGcgb:cg2383.
cgl:NCgl2091.
PATRIC21496344. VBICorGlu203724_2108.

Phylogenomic databases

HOGENOMHBG649727.
OMAITQMFFD.
PhylomeDBQ8NNM2.
ProtClustDBCLSK638719.

Family and domain databases

InterProIPR003171. Mehydrof_redctse.
IPR004620. MTHF_reductase_bac.
[Graphical view]
KOK00297.
PfamPF02219. MTHFR. 1 hit.
[Graphical view]
TIGRFAMsTIGR00676. Fadh2. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ8NNM2_CORGL
AccessionPrimary (citable) accession number: Q8NNM2
Secondary accession number(s): Q6M3R2
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: December 14, 2011
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info