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Protein

Cytochrome c oxidase polypeptide 4

Gene

ctaF

Organism
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of cytochrome c oxidase, its function is unknown.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciCORYNE:G18NG-11786-MONOMER.

Protein family/group databases

TCDBi3.D.4.4.2. the proton-translocating cytochrome oxidase (cox) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase polypeptide 4 (EC:1.9.3.1)
Alternative name(s):
Cytochrome aa3 subunit 4
Cytochrome c oxidase polypeptide IV
Gene namesi
Name:ctaF
Ordered Locus Names:Cgl2194, cg2408
OrganismiCorynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Taxonomic identifieri196627 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
Proteomesi
  • UP000000582 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 27HelicalSequence analysisAdd BLAST21
Transmembranei40 – 60HelicalSequence analysisAdd BLAST21
Transmembranei86 – 106HelicalSequence analysisAdd BLAST21
Transmembranei107 – 127HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002200151 – 143Cytochrome c oxidase polypeptide 4Add BLAST143

Interactioni

Subunit structurei

Associates with subunits I, II and III to form cytochrome c oxidase. The 4 subunit cytochrome c oxidase forms a supercomplex with cytochrome bc1.

Protein-protein interaction databases

STRINGi196627.cg2408.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105FK0. Bacteria.
ENOG4111R1D. LUCA.
HOGENOMiHOG000237887.
OMAiLVFEYYR.

Family and domain databases

InterProiIPR021050. Cyt_c_oxidase_su4_actinobac.
[Graphical view]
PfamiPF12270. Cyt_c_ox_IV. 1 hit.
[Graphical view]
PIRSFiPIRSF017385. CtaF. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8NNK3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSSAKLMYG PTVFMAAMAV IYIFATMHVS DGGSVKGVEW VGSVALVLSA
60 70 80 90 100
GLTLMLGVYL HFTEVRVDVL PEDWEEAEVA DKAGTLGFFS PSSIWPAAMS
110 120 130 140
GAVGFLAFGV VYFHYWMIAV GLMLLIFTIT KLNLQYGVPK EKH
Length:143
Mass (Da):15,545
Last modified:October 1, 2002 - v1
Checksum:i7DF43A2C4C2AC2CD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000036 Genomic DNA. Translation: BAB99587.1.
BX927154 Genomic DNA. Translation: CAF20535.1.
RefSeqiNP_601398.1. NC_003450.3.
WP_011014950.1. NC_006958.1.

Genome annotation databases

EnsemblBacteriaiBAB99587; BAB99587; BAB99587.
CAF20535; CAF20535; cg2408.
GeneIDi1020146.
KEGGicgb:cg2408.
cgl:NCgl2114.
PATRICi21496388. VBICorGlu203724_2130.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000036 Genomic DNA. Translation: BAB99587.1.
BX927154 Genomic DNA. Translation: CAF20535.1.
RefSeqiNP_601398.1. NC_003450.3.
WP_011014950.1. NC_006958.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi196627.cg2408.

Protein family/group databases

TCDBi3.D.4.4.2. the proton-translocating cytochrome oxidase (cox) superfamily.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB99587; BAB99587; BAB99587.
CAF20535; CAF20535; cg2408.
GeneIDi1020146.
KEGGicgb:cg2408.
cgl:NCgl2114.
PATRICi21496388. VBICorGlu203724_2130.

Phylogenomic databases

eggNOGiENOG4105FK0. Bacteria.
ENOG4111R1D. LUCA.
HOGENOMiHOG000237887.
OMAiLVFEYYR.

Enzyme and pathway databases

BioCyciCORYNE:G18NG-11786-MONOMER.

Family and domain databases

InterProiIPR021050. Cyt_c_oxidase_su4_actinobac.
[Graphical view]
PfamiPF12270. Cyt_c_ox_IV. 1 hit.
[Graphical view]
PIRSFiPIRSF017385. CtaF. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCOX4_CORGL
AccessioniPrimary (citable) accession number: Q8NNK3
Secondary accession number(s): Q6M3N9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: October 1, 2002
Last modified: November 2, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.