Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8NMT3

- GLSA_CORGL

UniProt

Q8NMT3 - GLSA_CORGL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutaminase

Gene

glsA

Organism
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei65 – 651SubstrateBy similarity
Binding sitei114 – 1141SubstrateBy similarity
Binding sitei160 – 1601SubstrateBy similarity
Binding sitei167 – 1671SubstrateBy similarity
Binding sitei191 – 1911SubstrateBy similarity
Binding sitei243 – 2431SubstrateBy similarity
Binding sitei261 – 2611Substrate; via amide nitrogenBy similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:Cgl2482, cg2728
OrganismiCorynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Taxonomic identifieri196627 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000000582: Chromosome, UP000001009: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 413413GlutaminasePRO_0000110606Add
BLAST

Interactioni

Subunit structurei

Homotetramer.By similarity

Protein-protein interaction databases

STRINGi196627.cg2728.

Structurei

3D structure databases

ProteinModelPortaliQ8NMT3.
SMRiQ8NMT3. Positions 3-349.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini316 – 41398STASAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni23 – 307285GlutaminaseAdd
BLAST

Sequence similaritiesi

Belongs to the glutaminase family.Curated
Contains 1 STAS domain.Curated

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiQCSVGVT.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.30.750.24. 1 hit.
3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
IPR002645. STAS_dom.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF52091. SSF52091. 1 hit.
SSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
PROSITEiPS50801. STAS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8NMT3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLTMPIPEYL HEILDDVRDT TSGELADYIP ELKSADPNPL AVALCTVNGH
60 70 80 90 100
IYSAGDDDIE FTMQSISKPF AYALALQECG FDEVSASVAL EPSGEAFNEL
110 120 130 140 150
SLDGENRPMN PMINAGAIAI NQLINGSDST VEDRVEKIRH YFSELAGREL
160 170 180 190 200
TIDRVLAESE LAGADRNLSI AHMLRNYGVI EDEAHDAVLS YTLQCAIKVT
210 220 230 240 250
TRDLAVMTAT LAAGGTHPIT GKKLLDARVC RLTLSVMASA GMYDEAGQWL
260 270 280 290 300
STVGIPAKSG VAGGLIGILP GQLGIATFSP RLNPKGNSVR GVKIFKQLSD
310 320 330 340 350
DMGLHLMSTE QVSGHAVRSI TRDGDTTFIQ MQGAMNFSAS ESFLHAIVEH
360 370 380 390 400
NFEGTEVVLD LTRVLSFHPV AIRMIKEGLK RIRDAGFEVF ILDPDDVLPD
410
FMFSDGTICK ERV
Length:413
Mass (Da):44,748
Last modified:May 24, 2004 - v2
Checksum:i91ADD397B9FFE473
GO

Sequence cautioni

The sequence BAB99875.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000036 Genomic DNA. Translation: BAB99875.1. Different initiation.
BX927155 Genomic DNA. Translation: CAF21143.1.
RefSeqiNP_601682.1. NC_003450.3.
YP_226722.1. NC_006958.1.

Genome annotation databases

EnsemblBacteriaiBAB99875; BAB99875; BAB99875.
CAF21143; CAF21143; cg2728.
GeneIDi1020428.
3342801.
KEGGicgl:NCgl2395.
PATRICi21496976. VBICorGlu203724_2414.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000036 Genomic DNA. Translation: BAB99875.1 . Different initiation.
BX927155 Genomic DNA. Translation: CAF21143.1 .
RefSeqi NP_601682.1. NC_003450.3.
YP_226722.1. NC_006958.1.

3D structure databases

ProteinModelPortali Q8NMT3.
SMRi Q8NMT3. Positions 3-349.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 196627.cg2728.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB99875 ; BAB99875 ; BAB99875 .
CAF21143 ; CAF21143 ; cg2728 .
GeneIDi 1020428.
3342801.
KEGGi cgl:NCgl2395.
PATRICi 21496976. VBICorGlu203724_2414.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi QCSVGVT.
OrthoDBi EOG6N94BK.

Family and domain databases

Gene3Di 3.30.750.24. 1 hit.
3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
IPR002645. STAS_dom.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF52091. SSF52091. 1 hit.
SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
PROSITEi PS50801. STAS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The Corynebacterium glutamicum genome: features and impacts on biotechnological processes."
    Ikeda M., Nakagawa S.
    Appl. Microbiol. Biotechnol. 62:99-109(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

Entry informationi

Entry nameiGLSA_CORGL
AccessioniPrimary (citable) accession number: Q8NMT3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: May 24, 2004
Last modified: November 26, 2014
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3