ID   DCD_CORGL               Reviewed;         189 AA.
AC   Q8NLT9;
DT   10-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   16-JUN-2009, entry version 35.
DE   RecName: Full=Deoxycytidine triphosphate deaminase;
DE            Short=dCTP deaminase;
DE            EC=3.5.4.13;
GN   Name=dcd; OrderedLocusNames=Cgl2848, cg3155;
OS   Corynebacterium glutamicum (Brevibacterium flavum).
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=1718;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025;
RA   Nakagawa S.;
RT   "Complete genomic sequence of Corynebacterium glutamicum ATCC 13032.";
RL   Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025;
RX   MEDLINE=22830012; PubMed=12948626; DOI=10.1016/S0168-1656(03)00154-8;
RA   Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M.,
RA   Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L.,
RA   Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B.,
RA   McHardy A.C., Meyer F., Moeckel B., Pfefferle W., Puehler A.,
RA   Rey D.A., Rueckert C., Rupp O., Sahm H., Wendisch V.F., Wiegraebe I.,
RA   Tauch A.;
RT   "The complete Corynebacterium glutamicum ATCC 13032 genome sequence
RT   and its impact on the production of L-aspartate-derived amino acids
RT   and vitamins.";
RL   J. Biotechnol. 104:5-25(2003).
CC   -!- CATALYTIC ACTIVITY: dCTP + H(2)O = dUTP + NH(3).
CC   -!- PATHWAY: Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP
CC       (dUTP route): step 1/2.
CC   -!- SIMILARITY: Belongs to the dCTP deaminase family.
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DR   EMBL; BA000036; BAC00242.1; -; Genomic_DNA.
DR   EMBL; BX927156; CAF20874.1; -; Genomic_DNA.
DR   RefSeq; NP_602041.1; -.
DR   RefSeq; YP_227090.1; -.
DR   HSSP; Q57872; 1OGH.
DR   GeneID; 1020792; -.
DR   GeneID; 3344679; -.
DR   GenomeReviews; BA000036_GR; Cgl2848.
DR   GenomeReviews; BX927147_GR; cg3155.
DR   KEGG; cgb:cg3155; -.
DR   KEGG; cgl:NCgl2751; -.
DR   HOGENOM; Q8NLT9; -.
DR   OMA; Q8NLT9; GSRYQGQ.
DR   BioCyc; CGLU196627-1:CG3155-MON; -.
DR   BRENDA; 3.5.4.13; 812.
DR   GO; GO:0008829; F:dCTP deaminase activity; IEA:HAMAP.
DR   GO; GO:0006229; P:dUTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0009220; P:pyrimidine ribonucleotide biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00146; -; 1.
DR   InterPro; IPR011962; dCTP_deam.
DR   InterPro; IPR008180; DeoxyUTPase.
DR   Pfam; PF00692; dUTPase; 1.
DR   ProDom; PD004900; dCTP_deaminase; 1.
DR   TIGRFAMs; TIGR02274; dCTP_deam; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Nucleotide metabolism.
FT   CHAIN         1    189       Deoxycytidine triphosphate deaminase.
FT                                /FTId=PRO_0000155982.
SQ   SEQUENCE   189 AA;  20689 MW;  820B4484A31A67EB CRC64;
     MLLSDRDIRK SIDAGDLGIE PFDAELIQPS SVDVRMDRYF RVFNNSKYTH IDPKLNQDEL
     TSLVEVEDGE GFVLHPGEFV LASTLEKFTL PAHLAGRLEG KSSLGRLGLL THSTAGFIDP
     GFSGYITLEL SNVANLPITL WPGMKVGQLA LFQMSSPAET PYGSGKLGSK YQGQRGPTPS
     KAYLNFPNK
//