Q8NLT9 (DCD_CORGL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Cgl2848, cg3155

Organism

Corynebacterium glutamicum (Brevibacterium flavum)

Taxonomic identifier

1718 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	189 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 189	189	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_0000155982

Sequences

	Sequence		Length	Mass (Da)
	Q8NLT9 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 820B4484A31A67EB	FASTA	189	20,689
	10 20 30 40 50 60 MLLSDRDIRK SIDAGDLGIE PFDAELIQPS SVDVRMDRYF RVFNNSKYTH IDPKLNQDEL 70 80 90 100 110 120 TSLVEVEDGE GFVLHPGEFV LASTLEKFTL PAHLAGRLEG KSSLGRLGLL THSTAGFIDP 130 140 150 160 170 180 GFSGYITLEL SNVANLPITL WPGMKVGQLA LFQMSSPAET PYGSGKLGSK YQGQRGPTPS KAYLNFPNK

References

[1]

"Complete genomic sequence of Corynebacterium glutamicum ATCC 13032." Nakagawa S. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

[2]

"The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins." Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F., Moeckel B. , Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O., Sahm H., Wendisch V.F., Wiegraebe I., Tauch A. J. Biotechnol. 104:5-25(2003) [PubMed: 12948626] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000036 Genomic DNA. Translation: BAC00242.1. BX927156 Genomic DNA. Translation: CAF20874.1.
RefSeq	NP_602041.1. NC_003450.3. YP_227090.1. NC_006958.1.
3D structure databases
ProteinModelPortal	Q8NLT9.
SMR	Q8NLT9. Positions 1-186.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1020792. 3344679.
GenomeReviews	Gene locus Cgl2848 in contig BA000036_GR. Gene locus cg3155 in contig BX927147_GR.
KEGG	cgb:cg3155. cgl:NCgl2751.
PATRIC	21497738. VBICorGlu203724_2781.
Phylogenomic databases
HOGENOM	HBG553199.
OMA	MEYFRIP.
PhylomeDB	Q8NLT9.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	CGLU196627:CG3155-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CORGL

Accession

Primary (citable) accession number: Q8NLT9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 10, 2003
Last sequence update:	October 1, 2002
Last modified:	January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program