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Protein

60S ribosomal protein L3

Gene

rpl3

Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

The L3 protein is a component of the large subunit of cytoplasmic ribosomes.Curated

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L3
Alternative name(s):
Allergen: Asp f 23
Gene namesi
Name:rpl3
ORF Names:AFUA_2G11850
OrganismiNeosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Taxonomic identifieri330879 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000002530 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiFungiDB:Afu2g11850.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Binds to IgE and IgG.1 Publication

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei1183. Asp f 23.
3117. Asp f 23.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000772441 – 39260S ribosomal protein L3Add BLAST392

Proteomic databases

PRIDEiQ8NKF4.

Structurei

3D structure databases

ProteinModelPortaliQ8NKF4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L3P family.Sequence analysis

Phylogenomic databases

HOGENOMiHOG000107319.
InParanoidiQ8NKF4.
KOiK02925.
OMAiVPRIRSW.
OrthoDBiEOG092C2SEF.

Family and domain databases

InterProiIPR000597. Ribosomal_L3.
IPR019926. Ribosomal_L3_CS.
IPR009000. Transl_B-barrel.
[Graphical view]
PfamiPF00297. Ribosomal_L3. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
PROSITEiPS00474. RIBOSOMAL_L3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8NKF4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHRKYEAPR HGSLAFLPRK RAARHRGKVK SFPKDDPKKP VHLTASMGYK
60 70 80 90 100
AGMTTVVRDL DRPGAKMHKK EIVEAVTIIE TPPLVAVGVV GYIETPRGLR
110 120 130 140 150
SLTTVWAEHL SDEVKRRFYK NWYKSKKKAF TKYAKKHAEE NGASITRELE
160 170 180 190 200
RIKKYCTVVR VLAHTQIRKT PLKQKKAHLM EIQVNGGSVA DKVDFARNLF
210 220 230 240 250
EKPIEIDSIF EKDEMIDVIA VTKGHGFQGV TSRWGTKKLP RKTHKGLRKV
260 270 280 290 300
ACIGAWHPSH VQWTVARAGQ MGYHHRTSCN HKVFRIGKGS DEGNASTDFD
310 320 330 340 350
ISKKQITPMG GFVRYGEVKN DYIMVKGSVP GVKKRVMTLR KTLYPQTSRR
360 370 380 390
ATEKVELKWI DTSSKFGHGA FQTPEEKRAF MGTLKKDLVT SA
Length:392
Mass (Da):44,445
Last modified:December 6, 2005 - v2
Checksum:i0A2D7C976D1023F5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti35D → Y in AAM43909 (PubMed:12974759).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF464911 mRNA. Translation: AAM43909.1.
AAHF01000001 Genomic DNA. Translation: EAL93479.1.
RefSeqiXP_755517.1. XM_750424.1.

Genome annotation databases

EnsemblFungiiCADAFUAT00004608; CADAFUAP00004608; CADAFUAG00004608.
GeneIDi3513239.
KEGGiafm:AFUA_2G11850.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF464911 mRNA. Translation: AAM43909.1.
AAHF01000001 Genomic DNA. Translation: EAL93479.1.
RefSeqiXP_755517.1. XM_750424.1.

3D structure databases

ProteinModelPortaliQ8NKF4.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei1183. Asp f 23.
3117. Asp f 23.0101.

Proteomic databases

PRIDEiQ8NKF4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADAFUAT00004608; CADAFUAP00004608; CADAFUAG00004608.
GeneIDi3513239.
KEGGiafm:AFUA_2G11850.

Organism-specific databases

EuPathDBiFungiDB:Afu2g11850.

Phylogenomic databases

HOGENOMiHOG000107319.
InParanoidiQ8NKF4.
KOiK02925.
OMAiVPRIRSW.
OrthoDBiEOG092C2SEF.

Family and domain databases

InterProiIPR000597. Ribosomal_L3.
IPR019926. Ribosomal_L3_CS.
IPR009000. Transl_B-barrel.
[Graphical view]
PfamiPF00297. Ribosomal_L3. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
PROSITEiPS00474. RIBOSOMAL_L3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL3_ASPFU
AccessioniPrimary (citable) accession number: Q8NKF4
Secondary accession number(s): Q4X0Y6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: December 6, 2005
Last modified: November 2, 2016
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.