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Protein
Submitted name:

Endoglucanase

Gene

cel12A

Organism
Humicola grisea
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Polysaccharide degradationUniRule annotation

Protein family/group databases

CAZyiGH12. Glycoside Hydrolase Family 12.
mycoCLAPiEGL12A_HUMGT.

Names & Taxonomyi

Protein namesi
Submitted name:
EndoglucanaseImported
Gene namesi
Name:cel12AImported
OrganismiHumicola griseaImported
Taxonomic identifieri5527 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesChaetomiaceaeHumicola

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717Sequence analysisAdd
BLAST
Chaini18 – 254237Sequence analysisPRO_5004311847Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi36 ↔ 65Combined sources

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1OLRX-ray1.20A32-254[»]
1UU4X-ray1.49A32-254[»]
1UU5X-ray1.67A32-254[»]
1UU6X-ray1.40A32-254[»]
1W2UX-ray1.52A32-254[»]
ProteinModelPortaliQ8NJY3.
SMRiQ8NJY3. Positions 31-254.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8NJY3.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 12 (cellulase H) family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di2.60.120.180. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR013319. GH11/12.
IPR002594. GH12.
[Graphical view]
PfamiPF01670. Glyco_hydro_12. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8NJY3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKSALLLGA AAVSVQSASI PTIPANLEPR QIRSLCELYG YWSGNGYELL
60 70 80 90 100
NNLWGKDTAT SGWQCTYLDG TNNGGIQWST AWEWQGAPDN VKSYPYVGKQ
110 120 130 140 150
IQRGRKISDI NSMRTSVSWT YDRTDIRANV AYDVFTARDP DHPNWGGDYE
160 170 180 190 200
LMIWLARYGG IYPIGTFHSQ VNLAGRTWDL WTGYNGNMRV YSFLPPSGDI
210 220 230 240 250
RDFSCDIKDF FNYLERNHGY PAREQNLIVY QVGTECFTGG PARFTCRDFR

ADLW
Length:254
Mass (Da):28,883
Last modified:March 1, 2004 - v2
Checksum:iE034A8FFABD22207
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF435071 Genomic DNA. Translation: AAM77714.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF435071 Genomic DNA. Translation: AAM77714.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1OLRX-ray1.20A32-254[»]
1UU4X-ray1.49A32-254[»]
1UU5X-ray1.67A32-254[»]
1UU6X-ray1.40A32-254[»]
1W2UX-ray1.52A32-254[»]
ProteinModelPortaliQ8NJY3.
SMRiQ8NJY3. Positions 31-254.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH12. Glycoside Hydrolase Family 12.
mycoCLAPiEGL12A_HUMGT.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiQ8NJY3.

Family and domain databases

Gene3Di2.60.120.180. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR013319. GH11/12.
IPR002594. GH12.
[Graphical view]
PfamiPF01670. Glyco_hydro_12. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ8NJY3_9PEZI
AccessioniPrimary (citable) accession number: Q8NJY3
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: March 1, 2004
Last modified: April 13, 2016
This is version 73 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.