Q8NI58 (Q8NI58_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Growth differentiation factor 3A EMBL AAM27000.1

Gene names

Name:

GDF3A EMBL AAM27000.1

Organism

Homo sapiens (Human) EMBL AAM27000.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	363 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the TGF-beta family. RuleBase RU000354

Ontologies

Keywords
Cellular component	Secreted SAAS SAAS015615
Molecular function	Growth factor RuleBase RU000354 SAAS SAAS015615
PTM	Disulfide bond SAAS SAAS015615
Gene Ontology (GO)
Biological process	growth Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	growth factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8NI58 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 76DB2A096A6B3158	FASTA	363	41,396
	10 20 30 40 50 60 MLRFLPDLAF SFLLILALGQ AVQFQEYVFL QFLGLDKAPS PHKFQPVPYI LKKIFQDREA 70 80 90 100 110 120 AATTGVSRDL CYVKELGVRG NVLRFLPDQG FFLYPKKISQ ASSCLQKLLY FNLSAIKERE 130 140 150 160 170 180 QLTLAQLVDL GPNSYYNLGP ELELALFLVQ EPHVWRQTTP KPGKMFVLRS VPWPQGAVHF 190 200 210 220 230 240 SLLDVAKDWN DNPRKNFGLF LEILVKENRD SGVNFQPEDT CARLRCSLHA SLLVVTLNPD 250 260 270 280 290 300 QCHPSRKRRA AIPVPKLSCK NLCHRHQLFI NFRDLGWHKW IIAPKGFMAN YCHGECPFSL 310 320 330 340 350 360 TISLNSSNYA FMQALMHAVD PEIPQAVCIP TKLSPISMLY QDNNDNVILR HYEDMVVDEC GCG

References

[1]	"Cloning of a novel human cDNA which is an alternative splicing form of human growth/differentiation factor 3 and termed hGDF3A." Yu L., Zhang H.L., Fu Q., Zhao Y. Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF110641 mRNA. Translation: AAM27000.1.
IPI	IPI00299659.
UniGene	Hs.86232.
3D structure databases
HSSP	HSSP built from PDB template 1NYS based on UniProtKB P08476.
ProteinModelPortal	Q8NI58.
SMR	Q8NI58. Positions 260-363.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8NI58.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG004860.
Gene expression databases
ArrayExpress	Q8NI58.
Family and domain databases
InterPro	IPR002405. Inhibin_asu. IPR001839. TGF-b_C. IPR001111. TGF-b_N. IPR015615. TGF-beta-rel. IPR017948. TGFb_CS. [Graphical view]
PANTHER	PTHR11848. TGFbeta. 1 hit.
Pfam	PF00019. TGF_beta. 1 hit. PF00688. TGFb_propeptide. 1 hit. [Graphical view]
PRINTS	PR00669. INHIBINA.
SMART	SM00204. TGFB. 1 hit. [Graphical view]
PROSITE	PS00250. TGF_BETA_1. 1 hit. PS51362. TGF_BETA_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8NI58_HUMAN

Accession

Primary (citable) accession number: Q8NI58

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.