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Protein

Zinc finger protein 28 homolog

Gene

ZFP28

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

May be involved in transcriptional regulation. May have a role in embryonic development.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri420 – 44223C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri448 – 47023C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri476 – 49924C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri505 – 52723C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri533 – 55523C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri561 – 58323C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri589 – 61123C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri617 – 63923C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri645 – 66723C2H2-type 9PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri673 – 69523C2H2-type 10PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri701 – 72323C2H2-type 11PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri729 – 75123C2H2-type 12PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri757 – 77923C2H2-type 13PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri785 – 80723C2H2-type 14PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri813 – 83523C2H2-type 15; degeneratePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-HSA-212436. Generic Transcription Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 28 homolog
Short name:
Zfp-28
Alternative name(s):
Krueppel-like zinc finger factor X6
Gene namesi
Name:ZFP28
Synonyms:KIAA1431
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:17801. ZFP28.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA38469.

Polymorphism and mutation databases

BioMutaiZFP28.
DMDMi33517131.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 868868Zinc finger protein 28 homologPRO_0000047289Add
BLAST

Proteomic databases

MaxQBiQ8NHY6.
PaxDbiQ8NHY6.
PRIDEiQ8NHY6.

PTM databases

iPTMnetiQ8NHY6.
PhosphoSiteiQ8NHY6.

Expressioni

Gene expression databases

BgeeiQ8NHY6.
CleanExiHS_ZFP28.
ExpressionAtlasiQ8NHY6. baseline and differential.
GenevisibleiQ8NHY6. HS.

Organism-specific databases

HPAiHPA028879.

Interactioni

Protein-protein interaction databases

BioGridi126637. 5 interactions.
IntActiQ8NHY6. 5 interactions.
MINTiMINT-8247395.
STRINGi9606.ENSP00000301318.

Structurei

Secondary structure

1
868
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Turni423 – 4253Combined sources
Helixi432 – 44211Combined sources
Beta strandi479 – 4813Combined sources
Beta strandi485 – 4873Combined sources
Helixi488 – 4958Combined sources
Turni496 – 5016Combined sources
Turni508 – 5103Combined sources
Beta strandi514 – 5163Combined sources
Helixi517 – 5248Combined sources
Turni525 – 5295Combined sources
Beta strandi532 – 5343Combined sources
Beta strandi536 – 5383Combined sources
Beta strandi541 – 5444Combined sources
Helixi545 – 5528Combined sources
Turni553 – 5553Combined sources
Beta strandi558 – 5603Combined sources
Turni564 – 5663Combined sources
Beta strandi571 – 5733Combined sources
Helixi574 – 5796Combined sources
Helixi580 – 5823Combined sources
Beta strandi588 – 5903Combined sources
Beta strandi592 – 5943Combined sources
Beta strandi597 – 6004Combined sources
Helixi601 – 61111Combined sources
Beta strandi616 – 6183Combined sources
Beta strandi620 – 6234Combined sources
Beta strandi625 – 6284Combined sources
Helixi629 – 63911Combined sources
Beta strandi644 – 6463Combined sources
Beta strandi648 – 6503Combined sources
Beta strandi653 – 6564Combined sources
Helixi657 – 66711Combined sources
Beta strandi668 – 6703Combined sources
Beta strandi676 – 6783Combined sources
Helixi685 – 69511Combined sources
Beta strandi700 – 7034Combined sources
Turni704 – 7074Combined sources
Helixi713 – 72412Combined sources
Beta strandi726 – 7305Combined sources
Beta strandi732 – 7343Combined sources
Beta strandi737 – 7404Combined sources
Helixi741 – 75111Combined sources
Beta strandi752 – 7554Combined sources
Beta strandi756 – 7583Combined sources
Beta strandi760 – 7623Combined sources
Beta strandi765 – 7684Combined sources
Helixi769 – 7768Combined sources
Helixi777 – 7793Combined sources
Beta strandi788 – 7903Combined sources
Helixi797 – 80610Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2EM2NMR-A584-616[»]
2EM3NMR-A640-672[»]
2EM4NMR-A724-756[»]
2EMJNMR-A612-644[»]
2EMKNMR-A668-700[»]
2EMLNMR-A752-784[»]
2EN9NMR-A415-447[»]
2ENHNMR-A556-588[»]
2EOHNMR-A780-812[»]
2EP0NMR-A528-560[»]
2EPXNMR-A471-504[»]
2EPZNMR-A500-532[»]
2YTMNMR-A696-728[»]
ProteinModelPortaliQ8NHY6.
SMRiQ8NHY6. Positions 103-143, 417-836.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8NHY6.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini103 – 17472KRAB 1PROSITE-ProRule annotationAdd
BLAST
Domaini232 – 29968KRAB 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 15 C2H2-type zinc fingers.PROSITE-ProRule annotation
Contains 2 KRAB domains.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri420 – 44223C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri448 – 47023C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri476 – 49924C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri505 – 52723C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri533 – 55523C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri561 – 58323C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri589 – 61123C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri617 – 63923C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri645 – 66723C2H2-type 9PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri673 – 69523C2H2-type 10PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri701 – 72323C2H2-type 11PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri729 – 75123C2H2-type 12PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri757 – 77923C2H2-type 13PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri785 – 80723C2H2-type 14PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri813 – 83523C2H2-type 15; degeneratePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00840000129692.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiQ8NHY6.
KOiK09228.
OMAiTGIYAGK.
OrthoDBiEOG7KSX7Q.
PhylomeDBiQ8NHY6.
TreeFamiTF341817.

Family and domain databases

Gene3Di3.30.160.60. 15 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 2 hits.
PF00096. zf-C2H2. 3 hits.
PF13912. zf-C2H2_6. 3 hits.
[Graphical view]
SMARTiSM00349. KRAB. 2 hits.
SM00355. ZnF_C2H2. 14 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 2 hits.
PROSITEiPS50805. KRAB. 2 hits.
PS00028. ZINC_FINGER_C2H2_1. 14 hits.
PS50157. ZINC_FINGER_C2H2_2. 15 hits.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q8NHY6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MRGAASASVR EPTPLPGRGA PRTKPRAGRG PTVGTPATLA LPARGRPRSR
60 70 80 90 100
NGLASKGQRG AAPTGPGHRA LPSRDTALPQ ERNKKLEAVG TGIEPKAMSQ
110 120 130 140 150
GLVTFGDVAV DFSQEEWEWL NPIQRNLYRK VMLENYRNLA SLGLCVSKPD
160 170 180 190 200
VISSLEQGKE PWTVKRKMTR AWCPDLKAVW KIKELPLKKD FCEGKLSQAV
210 220 230 240 250
ITERLTSYNL EYSLLGEHWD YDALFETQPG LVTIKNLAVD FRQQLHPAQK
260 270 280 290 300
NFCKNGIWEN NSDLGSAGHC VAKPDLVSLL EQEKEPWMVK RELTGSLFSG
310 320 330 340 350
QRSVHETQEL FPKQDSYAEG VTDRTSNTKL DCSSFRENWD SDYVFGRKLA
360 370 380 390 400
VGQETQFRQE PITHNKTLSK ERERTYNKSG RWFYLDDSEE KVHNRDSIKN
410 420 430 440 450
FQKSSVVIKQ TGIYAGKKLF KCNECKKTFT QSSSLTVHQR IHTGEKPYKC
460 470 480 490 500
NECGKAFSDG SSFARHQRCH TGKKPYECIE CGKAFIQNTS LIRHWRYYHT
510 520 530 540 550
GEKPFDCIDC GKAFSDHIGL NQHRRIHTGE KPYKCDVCHK SFRYGSSLTV
560 570 580 590 600
HQRIHTGEKP YECDVCRKAF SHHASLTQHQ RVHSGEKPFK CKECGKAFRQ
610 620 630 640 650
NIHLASHLRI HTGEKPFECA ECGKSFSISS QLATHQRIHT GEKPYECKVC
660 670 680 690 700
SKAFTQKAHL AQHQKTHTGE KPYECKECGK AFSQTTHLIQ HQRVHTGEKP
710 720 730 740 750
YKCMECGKAF GDNSSCTQHQ RLHTGQRPYE CIECGKAFKT KSSLICHRRS
760 770 780 790 800
HTGEKPYECS VCGKAFSHRQ SLSVHQRIHS GKKPYECKEC RKTFIQIGHL
810 820 830 840 850
NQHKRVHTGE RSYNYKKSRK VFRQTAHLAH HQRIHTGESS TCPSLPSTSN
860
PVDLFPKFLW NPSSLPSP
Length:868
Mass (Da):98,705
Last modified:October 1, 2002 - v1
Checksum:iE5959243B41CE3F3
GO
Isoform 2 (identifier: Q8NHY6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     301-349: QRSVHETQEL...DSDYVFGRKL → ECRRAWCGKS...ERKLNSGSSK
     350-868: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:349
Mass (Da):38,512
Checksum:iDC42BF404E6EDC5C
GO

Sequence cautioni

The sequence BAA92669.1 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti10 – 101R → H in AAH28416 (PubMed:15489334).Curated
Sequence conflicti10 – 101R → H in AAH99903 (PubMed:15489334).Curated
Sequence conflicti383 – 3831F → S in BAA92669 (PubMed:10718198).Curated
Sequence conflicti766 – 78520Missing (Ref. 5) CuratedAdd
BLAST
Isoform 2 (identifier: Q8NHY6-2)
Sequence conflicti324 – 3241S → F in AAH28416 (PubMed:15489334).Curated
Sequence conflicti324 – 3241S → F in AAH99903 (PubMed:15489334).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti141 – 1411S → W.
Corresponds to variant rs34136271 [ dbSNP | Ensembl ].
VAR_052738
Natural varianti620 – 6201A → V.
Corresponds to variant rs10409531 [ dbSNP | Ensembl ].
VAR_024190

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei301 – 34949QRSVH…FGRKL → ECRRAWCGKSTARESGAFTK KAASSLIYSRKLYPGSLGLE RKLNSGSSK in isoform 2. 1 PublicationVSP_055934Add
BLAST
Alternative sequencei350 – 868519Missing in isoform 2. 1 PublicationVSP_055935Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF507045 mRNA. Translation: AAM28892.1.
AB037852 mRNA. Translation: BAA92669.1. Different initiation.
AC005498 Genomic DNA. No translation available.
BC028416 mRNA. Translation: AAH28416.1.
BC099903 mRNA. Translation: AAH99903.1.
BC127003 mRNA. Translation: AAI27004.1.
AF226995 mRNA. Translation: AAK28320.1.
CCDSiCCDS12946.1. [Q8NHY6-1]
CCDS77363.1. [Q8NHY6-2]
RefSeqiNP_001295369.1. NM_001308440.1. [Q8NHY6-2]
NP_065879.1. NM_020828.1. [Q8NHY6-1]
UniGeneiHs.14794.

Genome annotation databases

EnsembliENST00000301318; ENSP00000301318; ENSG00000196867. [Q8NHY6-1]
ENST00000591844; ENSP00000468603; ENSG00000196867. [Q8NHY6-2]
GeneIDi140612.
KEGGihsa:140612.
UCSCiuc002qni.4. human. [Q8NHY6-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF507045 mRNA. Translation: AAM28892.1.
AB037852 mRNA. Translation: BAA92669.1. Different initiation.
AC005498 Genomic DNA. No translation available.
BC028416 mRNA. Translation: AAH28416.1.
BC099903 mRNA. Translation: AAH99903.1.
BC127003 mRNA. Translation: AAI27004.1.
AF226995 mRNA. Translation: AAK28320.1.
CCDSiCCDS12946.1. [Q8NHY6-1]
CCDS77363.1. [Q8NHY6-2]
RefSeqiNP_001295369.1. NM_001308440.1. [Q8NHY6-2]
NP_065879.1. NM_020828.1. [Q8NHY6-1]
UniGeneiHs.14794.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2EM2NMR-A584-616[»]
2EM3NMR-A640-672[»]
2EM4NMR-A724-756[»]
2EMJNMR-A612-644[»]
2EMKNMR-A668-700[»]
2EMLNMR-A752-784[»]
2EN9NMR-A415-447[»]
2ENHNMR-A556-588[»]
2EOHNMR-A780-812[»]
2EP0NMR-A528-560[»]
2EPXNMR-A471-504[»]
2EPZNMR-A500-532[»]
2YTMNMR-A696-728[»]
ProteinModelPortaliQ8NHY6.
SMRiQ8NHY6. Positions 103-143, 417-836.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126637. 5 interactions.
IntActiQ8NHY6. 5 interactions.
MINTiMINT-8247395.
STRINGi9606.ENSP00000301318.

PTM databases

iPTMnetiQ8NHY6.
PhosphoSiteiQ8NHY6.

Polymorphism and mutation databases

BioMutaiZFP28.
DMDMi33517131.

Proteomic databases

MaxQBiQ8NHY6.
PaxDbiQ8NHY6.
PRIDEiQ8NHY6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000301318; ENSP00000301318; ENSG00000196867. [Q8NHY6-1]
ENST00000591844; ENSP00000468603; ENSG00000196867. [Q8NHY6-2]
GeneIDi140612.
KEGGihsa:140612.
UCSCiuc002qni.4. human. [Q8NHY6-1]

Organism-specific databases

CTDi140612.
GeneCardsiZFP28.
HGNCiHGNC:17801. ZFP28.
HPAiHPA028879.
neXtProtiNX_Q8NHY6.
PharmGKBiPA38469.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00840000129692.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiQ8NHY6.
KOiK09228.
OMAiTGIYAGK.
OrthoDBiEOG7KSX7Q.
PhylomeDBiQ8NHY6.
TreeFamiTF341817.

Enzyme and pathway databases

ReactomeiR-HSA-212436. Generic Transcription Pathway.

Miscellaneous databases

ChiTaRSiZFP28. human.
EvolutionaryTraceiQ8NHY6.
GenomeRNAii140612.
PROiQ8NHY6.

Gene expression databases

BgeeiQ8NHY6.
CleanExiHS_ZFP28.
ExpressionAtlasiQ8NHY6. baseline and differential.
GenevisibleiQ8NHY6. HS.

Family and domain databases

Gene3Di3.30.160.60. 15 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 2 hits.
PF00096. zf-C2H2. 3 hits.
PF13912. zf-C2H2_6. 3 hits.
[Graphical view]
SMARTiSM00349. KRAB. 2 hits.
SM00355. ZnF_C2H2. 14 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 2 hits.
PROSITEiPS50805. KRAB. 2 hits.
PS00028. ZINC_FINGER_C2H2_1. 14 hits.
PS50157. ZINC_FINGER_C2H2_2. 15 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Identification and characterization of two novel zinc finger genes, ZNF359 and ZFP28, in human development."
    Zhou L., Zhu C., Luo K., Li Y., Pi H., Yuan W., Wang Y., Huang C., Liu M., Wu X.
    Biochem. Biophys. Res. Commun. 295:862-868(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  2. "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."
    Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O.
    DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain.
  3. "The DNA sequence and biology of human chromosome 19."
    Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
    , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
    Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Tissue: Brain and Testis.
  5. "Identification of C2H2 zinc finger factor sequences in human heart."
    Brand N.J., Mullen A.J., Barton P.J.R.
    Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 446-868 (ISOFORM 1).
    Tissue: Heart muscle.
  6. "Solution structure of the C2H2 type zinc finger region of human zinc finger protein 28 homolog."
    RIKEN structural genomics initiative (RSGI)
    Submitted (OCT-2007) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 415-812.

Entry informationi

Entry nameiZFP28_HUMAN
AccessioniPrimary (citable) accession number: Q8NHY6
Secondary accession number(s): A0JNV6
, K7ES88, Q8NHU8, Q9BY30, Q9P2B6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 4, 2003
Last sequence update: October 1, 2002
Last modified: June 8, 2016
This is version 131 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.