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Protein

Spermatogenesis-associated protein 3

Gene

SPATA3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Spermatogenesis-associated protein 3
Alternative name(s):
Testis and spermatogenesis cell-related protein 1
Testis spermatocyte apoptosis-related protein 1
Gene namesi
Name:SPATA3
Synonyms:TSARG1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000173699.15.
HGNCiHGNC:17884. SPATA3.
neXtProtiNX_Q8NHX4.

Pathology & Biotechi

Organism-specific databases

DisGeNETi130560.
OpenTargetsiENSG00000173699.
PharmGKBiPA38256.

Polymorphism and mutation databases

BioMutaiSPATA3.
DMDMi41704647.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000721741 – 192Spermatogenesis-associated protein 3Add BLAST192

Proteomic databases

PaxDbiQ8NHX4.
PeptideAtlasiQ8NHX4.
PRIDEiQ8NHX4.

PTM databases

iPTMnetiQ8NHX4.
PhosphoSitePlusiQ8NHX4.

Expressioni

Gene expression databases

BgeeiENSG00000173699.
ExpressionAtlasiQ8NHX4. baseline and differential.
GenevisibleiQ8NHX4. HS.

Interactioni

Protein-protein interaction databases

BioGridi126241. 8 interactors.
STRINGi9606.ENSP00000388741.

Structurei

3D structure databases

ProteinModelPortaliQ8NHX4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410JCCC. Eukaryota.
ENOG41113TY. LUCA.
GeneTreeiENSGT00390000003032.
HOGENOMiHOG000276896.
HOVERGENiHBG062640.
InParanoidiQ8NHX4.
OMAiAAPQSRK.
OrthoDBiEOG091G135A.
PhylomeDBiQ8NHX4.
TreeFamiTF338040.

Family and domain databases

InterProiView protein in InterPro
IPR026717. SPATA3.
PANTHERiPTHR22234. PTHR22234. 1 hit.
PfamiView protein in Pfam
PF15662. SPATA3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8NHX4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKVKKKRSE ARRHRDSTSQ HASSNSTSQQ PSPESTPQQP SPESTPQQPS
60 70 80 90 100
PESTPQHSSL ETTSRQPAFQ ALPAPEIRRS SCCLLSPDAN VKAAPQSRKA
110 120 130 140 150
GPLIRAGPHS CSCATCPCSS ACWRRLGLCH SRIFDVLLPR DWQMAPGRGL
160 170 180 190
PNLLTFYRKS SRKPSSHRNA CPPSPRNCGC GSGGSRSCLL HH
Length:192
Mass (Da):20,901
Last modified:April 16, 2014 - v2
Checksum:iCC2E2B60D4A2CD11
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti104I → T in AAH47704 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_07080841 – 49Missing . 9

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY032925 mRNA. Translation: AAK54455.1.
AK093385 mRNA. Translation: BAC04149.1.
AC009407 Genomic DNA. No translation available.
AC105344 Genomic DNA. No translation available.
BC047704 mRNA. Translation: AAH47704.1.
CCDSiCCDS2481.1.
RefSeqiNP_620712.2. NM_139073.3.
XP_005246360.1. XM_005246303.2.
XP_016858852.1. XM_017003363.1.
UniGeneiHs.745178.

Genome annotation databases

EnsembliENST00000424440; ENSP00000399514; ENSG00000173699.
ENST00000433428; ENSP00000403804; ENSG00000173699.
ENST00000452881; ENSP00000388895; ENSG00000173699.
ENST00000455816; ENSP00000388741; ENSG00000173699.
GeneIDi130560.
KEGGihsa:130560.
UCSCiuc002vri.5. human.

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiSPTA3_HUMAN
AccessioniPrimary (citable) accession number: Q8NHX4
Secondary accession number(s): Q86WX5, Q8N9Y6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: April 16, 2014
Last modified: September 27, 2017
This is version 102 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations