Unreviewed,
UniProtKB/TrEMBL Q8NHX1 (Q8NHX1_HUMAN)
Last modified
February 9, 2010.
Version 67.
History...
Clusters with 100%,
90%,
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information
Names and origin
| Protein names | Submitted name: Extracellular signal-related kinase 1b EMBL AAK52329.1 |
| Organism | Homo sapiens (Human) EMBL AAK52329.1 |
| Taxonomic identifier | 9606 [NCBI] |
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Protein attributes
| Sequence length | 357 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Catalytic activity | ATP + a protein = ADP + a phosphoprotein. Spearmint SPM003527 |
| Sequence similarities | Contains 1 protein kinase domain. |
Ontologies
| Keywords | |
|---|---|
| Ligand | ATP-binding Spearmint SPM003527 RuleBase RU000304V2 Nucleotide-binding |
| Molecular function | Kinase Serine/threonine-protein kinase Spearmint SPM003527 Transferase |
| Gene Ontology (GO) | |
| Biological process | protein amino acid phosphorylation Inferred from electronic annotation. Source: InterPro |
| Cellular component | cytoskeleton Inferred from direct assay. Source: HPA nucleusInferred from direct assay. Source: HPA |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW MAP kinase activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequences
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References
| [1] | "Properties of human ERK1b." Aebersold D.M., Yung Y., Seger R. Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AY033607 mRNA. Translation: AAK52329.1. |
| IPI | IPI00742900. |
| RefSeq | NP_001035145.1. |
| UniGene | Hs.861 |
3D structure databases | |
| HSSP | HSSP built from PDB template 1PME based on UniProtKB P28482. |
| SMR | Q8NHX1. Positions 19-344. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q8NHX1. |
Genome annotation databases | |
| Ensembl | ENST00000395199; ENSP00000378625; ENSG00000102882; Homo sapiens. [Genome view] ENST00000403394; ENSP00000384895; ENSG00000102882; Homo sapiens. [Genome view] |
| GeneID | 5595. |
| KEGG | hsa:5595. |
| UCSC | uc002dwt.1. human. |
Organism-specific databases | |
| CTD | 5595. |
| HGNC | HGNC:6877. MAPK3. |
Phylogenomic databases | |
| HOVERGEN | Q8NHX1. |
| PhylomeDB | Q8NHX1. |
Gene expression databases | |
| ArrayExpress | Q8NHX1. |
| Bgee | Q8NHX1. |
Family and domain databases | |
| InterPro | IPR008349. Erk_1_2_MAPK. IPR011009. Kinase-like_dom. IPR003527. MAP_kinase_CS. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_prot_kinase-like_dom. IPR002290. Ser/Thr_prot_kinase_dom. [Graphical view] |
| Pfam | PF00069. Pkinase. 1 hit. [Graphical view] |
| PRINTS | PR01770. ERK1ERK2MAPK. |
| SMART | SM00220. S_TKc. 1 hit. [Graphical view] |
| PROSITE | PS01351. MAPK. 1 hit. PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 21714. |
Entry information
| Entry name | Q8NHX1_HUMAN | ||||||||
| Accession | Primary (citable) accession number: Q8NHX1 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||
| Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. | ||||||||
